Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Melanie N. Kuehl"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Saliva has immense potential as a diagnostic fluid for identification and monitoring of several systemic diseases. Composition of the microbiome and inflammation has been associated and reflective of oral and overall health. In addition, the
Externí odkaz:
https://doaj.org/article/30f45f65763945aa938639ea51350274
Autor:
Catherine B. MarElia, Melanie N. Kuehl, Tiffany A. Shemwell, Amy C. Alman, Brant R. Burkhardt
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 11, Iss , Pp 26-30 (2018)
Aim: PANcreatic-DERived factor (PANDER, FAM3B) is a novel hormone that regulates glucose levels via interaction with both the endocrine pancreas and liver. Prior studies examining PANDER were primarily conducted in murine models or in vitro but littl
Externí odkaz:
https://doaj.org/article/f6fa4444a3e24e28b81f1743acf7ba53
Autor:
Shari L. Moak, Grace C. Dougan, Catherine B. MarElia, Whitney A. Danse, Amanda M. Fernandez, Melanie N. Kuehl, Mark G. Athanason, Brant R. Burkhardt
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1307-1315 (2014)
Pancreatic-derived factor (PANDER; also known as FAM3B) is a uniquely structured protein strongly expressed within and secreted from the endocrine pancreas. PANDER has been hypothesized to regulate fasting and fed glucose homeostasis, hepatic lipogen
Externí odkaz:
https://doaj.org/article/5d48683149f1492aa6efbaa4439f360c
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125320 (2015)
Type 1 diabetes (T1D) is an autoimmune disease resulting in the targeted destruction of pancreatic β-cells and permanent loss of insulin production. Proper glucose management results in better clinical outcomes for T1D and provides a strong rational
Externí odkaz:
https://doaj.org/article/82bda052d4344cfd84bb42d3a101c25d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Saliva has immense potential as a diagnostic fluid for identification and monitoring of several systemic diseases. Composition of the microbiome and inflammation has been associated and reflective of oral and overall health. In addition, the relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36cb2d0e79c2d337a61f98fc43e2f45
https://doi.org/10.1038/s41598-021-81420-3
https://doi.org/10.1038/s41598-021-81420-3
Autor:
Brant R. Burkhardt, Tiffany A. Shemwell, Melanie N. Kuehl, Amy C. Alman, Catherine B. MarElia
Publikováno v:
Journal of Clinical & Translational Endocrinology
Journal of Clinical & Translational Endocrinology, Vol 11, Iss, Pp 26-30 (2018)
Journal of Clinical & Translational Endocrinology, Vol 11, Iss, Pp 26-30 (2018)
Highlights • PANcreatic-DERived factor (PANDER) is a novel hormone regulating glucose levels. • Fasting PANDER levels were measured in T2D and non-T2D matched subjects from U.S. • Associations between PANDER and other hormones or metabolic para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dba03dd032d709e6f5dcbe2b3a03f7
https://doi.org/10.1016/j.jcte.2018.02.003
https://doi.org/10.1016/j.jcte.2018.02.003
Autor:
Catherine B. MarElia, Whitney A. Ratliff, Stanley M. Stevens, Melanie N. Kuehl, Mark G. Athanason, Brant R. Burkhardt, Dale Chaput
Publikováno v:
Molecular and Cellular Endocrinology. 436:41-49
PANcreatic-DERived factor (PANDER) is a member of a superfamily of FAM3 proteins modulating glycemic levels by metabolic regulation of the liver and pancreas. The precise PANDER-induced hepatic signaling mechanism is still being elucidated and has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d64ff7a25ebe13a4916add7b40e4d1
https://doi.org/10.1016/j.mce.2016.07.009
https://doi.org/10.1016/j.mce.2016.07.009
Autor:
Whitney A. Ratliff, Amanda M. Fernandez, Catherine B. MarElia, Melanie N. Kuehl, Brant R. Burkhardt, Mark G. Athanason, Alicia C. Chechele
Publikováno v:
Molecular and Cellular Endocrinology. 413:101-112
PANcreatic-DERived factor (PANDER, FAM3B) has been shown to regulate glycemic levels via interactions with both pancreatic islets and the liver. Although PANDER is predominantly expressed from the endocrine pancreas, recent work has provided sufficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892a554b6f1be2cef20ff1b9005fda10
https://doi.org/10.1016/j.mce.2015.05.040
https://doi.org/10.1016/j.mce.2015.05.040
Autor:
Melanie N. Kuehl, Stanley M. Stevens, Shari L. Moak, Harris Bell-Temin, Brant R. Burkhardt, Grace C. Dougan, Mark G. Athanason, Claudia E. Robert-Cooperman
Publikováno v:
Journal of Endocrinology. 220:219-231
PANcreatic-DERived factor (PANDER, FAM3B) is a novel protein that is highly expressed within the endocrine pancreas and to a lesser degree in other tissues. Under glucose stimulation, PANDER is co-secreted with insulin from the β-cell. Despite prior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beefc3b4a7c271963d5ad4c78e740fac
https://doi.org/10.1530/joe-13-0338
https://doi.org/10.1530/joe-13-0338
Autor:
Catherine B. MarElia, Shari L. Moak, Grace C. Dougan, Brant R. Burkhardt, Melanie N. Kuehl, Mark G. Athanason, Whitney A. Danse, Amanda M. Fernandez
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1307-1315 (2014)
Disease Models & Mechanisms, Vol 7, Iss 11, Pp 1307-1315 (2014)
Pancreatic-derived factor (PANDER; also known as FAM3B) is a uniquely structured protein strongly expressed within and secreted from the endocrine pancreas. PANDER has been hypothesized to regulate fasting and fed glucose homeostasis, hepatic lipogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1800602f0fd7adc080c2331864dda24
https://doi.org/10.1242/dmm.016402
https://doi.org/10.1242/dmm.016402