Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Melanie M. White"'
Autor:
S. N. Hill, Lisa K. Jennings, Teddi J. Kueter, Angela D. Earhart, Shila Cholera, H. E. Speich, Melanie M. White, J. N. Smith
Publikováno v:
Journal of Thrombosis and Haemostasis. 7:983-991
Summary. Background: Utilization of glycoprotein IIb–IIIa (GPIIb–IIIa) inhibitors improves outcomes of patients with acute coronary syndromes (ACS), including those undergoing percutaneous coronary intervention (PCI). These results may be related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dba6d037fa4db379cd38c894e84664
https://doi.org/10.1111/j.1538-7836.2009.03432.x
https://doi.org/10.1111/j.1538-7836.2009.03432.x
Autor:
Michael J. Herr, Ed Hord, Dietmar Seiffert, Jayaprakash Kotha, Mason L. A. Dixon, Melanie M. White, Vinay Bhal, Steve Akins, Lisa K. Jennings
Publikováno v:
Thrombosis research. 136(6)
Introduction Dual anti-platelet therapy (DAPT) with aspirin and a P2Y 12 antagonist is standard of care to reduce risk of thrombosis, but does not directly target thrombin-dependent platelet activation. Therefore, PAR-1 antagonist addition to DAPT (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea258b412cb48cc89200e230430b9a8c
https://pubmed.ncbi.nlm.nih.gov/26548621
https://pubmed.ncbi.nlm.nih.gov/26548621
Publikováno v:
Journal of Thrombosis and Thrombolysis. 18:163-169
Objective: To evaluate a newly modified rapid platelet function analysis system (ICHOR/ Plateletworks®) and to compare the results obtained with those of traditional light transmission aggregometry (LTA), and the Ultegra/RPFA® system. Background: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cb3d43f64cd473ef024b0c90280f74
https://doi.org/10.1007/s11239-005-0341-x
https://doi.org/10.1007/s11239-005-0341-x
Publikováno v:
Journal of Thrombosis and Haemostasis. 1:576-586
We investigated the direct role of cholesterol lowering on human platelet aggregation by in vitro cholesterol depletion using methyl-beta-cyclodextrin. Collagen and thrombin receptor agonist peptide induced maximal aggregation was significantly decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c647153c7f537063c963d70bb577d1
https://doi.org/10.1046/j.1538-7836.2003.00087.x
https://doi.org/10.1046/j.1538-7836.2003.00087.x
Autor:
Joseph T. Crossno, Rajendra Raghow, Jianxong Bao, Celia M. Longhurst, Deborah A. Fitzgerald, Lisa K. Jennings, Thomas J. Fitzgerald, Melanie M. White, Jonathan D. Jacobs
Publikováno v:
Journal of Biological Chemistry. 277:32445-32452
CD9, a member of the tetraspanin family of proteins, is characterized by four transmembrane domains and two extracellular loops. Surface expression of CD9 on Chinese hamster ovary (CHO) cells dramatically enhances spreading and motility on fibronecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3da72507583647c0e7f0e83384e3af2
https://doi.org/10.1074/jbc.m204420200
https://doi.org/10.1074/jbc.m204420200
Publikováno v:
Journal of Interventional Cardiology. 15:45-60
Glycoprotein (GP) IIb/IIIa antagonists are a unique class of antiplatelet agents introduced for the management of patients undergoing percutaneous coronary intervention (PCI) and those presenting with unstable angina or non-ST segment elevation (NSTE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdc82e7997a66ec79145c46a98b5586
https://doi.org/10.1111/j.1540-8183.2002.tb01034.x
https://doi.org/10.1111/j.1540-8183.2002.tb01034.x
Publikováno v:
Blood. 96:2487-2495
Glycoprotein (GP) IIb-IIIa plays a critical role in platelet aggregation and platelet-mediated clot retraction. This study examined the intramolecular relationship between GPIIb-IIIa activation and fibrinogen binding, platelet aggregation, and platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61cdabf6b3092c8310d147b97c9578d6
https://doi.org/10.1182/blood.v96.7.2487
https://doi.org/10.1182/blood.v96.7.2487
Publikováno v:
European Journal of Biochemistry. 263:104-110
A noncovalently associated complex comprising of CD9, the fibrinogen (Fg) receptor alphaIIbbeta3, integrin-associated protein (IAP), and glycoprotein (GP) Ib/V/IX complex was isolated from Chaps-solubilized human platelets. The CD9 complex was immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4d2bce71d00c2f56b1f907518dc322
https://doi.org/10.1046/j.1432-1327.1999.00467.x
https://doi.org/10.1046/j.1432-1327.1999.00467.x
Autor:
Basel A. Abushullaih, Deepthi Jayawardene, Carl W. Jackson, Najat C. Daw, Deo Kumar Srivastava, Paula E. Stenberg, Julie T. Arnold, Melanie M. White
Publikováno v:
Blood. 91:466-474
The thrombopoietic efficacy of recombinant forms of c-mplligand is being actively investigated in preclinical studies using daily dosing schedules. However, a comprehensive kinetic study of the thrombopoietic response to a single injection of recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3413951417f511ba85b1c2b56c35d5d
https://doi.org/10.1182/blood.v91.2.466.466_466_474
https://doi.org/10.1182/blood.v91.2.466.466_466_474
Publikováno v:
Thrombosis and Haemostasis. 80:42-48
SummaryPlatelets from Glanzmann thrombasthenia patient BL express approximately 30% of the normal αIIbβ3 content and support fibrin-mediated clot retraction, but fail to bind fibrinogen or aggregate following cellular activation. BL platelets bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cece25d22dc3c831c325f21d6bdd6c0
https://doi.org/10.1055/s-0037-1615136
https://doi.org/10.1055/s-0037-1615136