Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melanie M. Pleiss"'
Autor:
Susan D. Kraner, Melanie M. Pleiss, Jennifer L. Furman, M. Paul Murphy, Christopher M. Norris, Greg A. Gerhardt, Jorge E. Quintero, Mark A. Lovell, Irina A. Artiushin, Pradoldej Sompol, Tina L. Beckett, Linda A. Simmerman, Seth R. Batten
Publikováno v:
The Journal of Neuroscience. 37:6132-6148
Hyperexcitable neuronal networks are mechanistically linked to the pathologic and clinical features of Alzheimer's disease (AD). Astrocytes are a primary defense against hyperexcitability, but their functional phenotype during AD is poorly understood
Autor:
Donna M. Wilcock, Erica M. Weekman, Abigail E. Woolums, Christopher M. Norris, Melanie M. Pleiss, Tiffany L. Sudduth
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Peter T. Nelson, Jennifer L. Furman, Christopher M. Norris, Rodney P. Guttmann, Susan D. Kraner, Donna M. Wilcock, Hafiz Mohmmad Abdul, Pradoldej Sompol, Melanie M. Pleiss
Publikováno v:
Biochimica et biophysica acta. 1862(9)
Mounting evidence suggests that astrocyte activation, found in most forms of neural injury and disease, is linked to the hyperactivation of the protein phosphatase calcineurin. In many tissues and cell types, calcineurin hyperactivity is the direct r
P3‐069: A NOVEL REAGENT MODULATES CN/CX43 INTERACTIONS DURING THE PROGRESSION OF ALZHEIMER'S DISEASE
Publikováno v:
Alzheimer's & Dementia. 10
age-dependent decline of the chaperones-assisted mechanisms is thought to contribute to proteostasis diseases, including amyloidoses. Clusterin is a chaperone implicated in the processing of misfolded and aggregated extracellular proteins, with a mec
Autor:
Melanie M. Pleiss, Peter T. Nelson, Christopher M. Norris, Donna M. Wilcock, Ela Patel, Hafiz Mohmmad Abdul, Jennifer L. Furman, Rodney P. Guttmann
Publikováno v:
Alzheimer's & Dementia. 10
Autor:
Melanie M. Pleiss, Dieter Pagani, Katie McCarty, Jonathan A. Nitz, Amy L.S. Dowling, Frederick Bresch, Jeffery R. Smiley, Curt Hendrix, Mike Grossheim, M. Paul Murphy, Elizabeth Head, Heather L. Murphey, Samuel R. Bethel, Tina L. Beckett, Jenna L. VanRooyen
Publikováno v:
Journal of Alzheimer's disease : JAD. 32(4)
Alzheimer's disease (AD) involves multiple pathological processes in the brain, including increased inflammation and oxidative damage, as well as the accumulation of amyloid-β (Aβ) plaques. We hypothesized that a combinatorial therapeutic approach
Autor:
Head E; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536-0230, USA. Elizabeth.Head@uky.edu, Murphey HL, Dowling AL, McCarty KL, Bethel SR, Nitz JA, Pleiss M, Vanrooyen J, Grossheim M, Smiley JR, Murphy MP, Beckett TL, Pagani D, Bresch F, Hendrix C
Publikováno v:
Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2012; Vol. 32 (4), pp. 1029-42.