Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melanie M. Mandl"'
Autor:
Martina Meßner, Melanie M. Mandl, Mathias W. Hackl, Till Reinhardt, Maximilian A. Ardelt, Karolina Szczepanowska, Julian E. Frädrich, Jens Waschke, Irmela Jeremias, Anja Fux, Matthias Stahl, Angelika M. Vollmar, Stephan A. Sieber, Johanna Pachmayr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The human mitochondrial ClpXP protease complex (HsClpXP) has recently attracted major attention as a target for novel anti-cancer therapies. Despite its important role in disease progression, the cellular role of HsClpXP is poorly characteri
Externí odkaz:
https://doaj.org/article/547435541d554b50bc1ec5f3fc98a476
Autor:
Mathias W. Hackl, Till Reinhardt, Karolina Szczepanowska, Angelika M. Vollmar, Melanie M Mandl, Maximilian A Ardelt, Anja Fux, Irmela Jeremias, Stephan A. Sieber, Jens Waschke, Martina Meßner, Matthias Stahl, Julian E Frädrich, Johanna Pachmayr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Sci. Rep. 11:11185 (2021)
Scientific Reports
Sci. Rep. 11:11185 (2021)
Scientific Reports
The human mitochondrial ClpXP protease complex (HsClpXP) has recently attracted major attention as a target for novel anti-cancer therapies. Despite its important role in disease progression, the cellular role of HsClpXP is poorly characterized and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33dc8fd0c7e9d8590c5c69fc7b6b8b4c
https://doi.org/10.1038/s41598-021-90801-7
https://doi.org/10.1038/s41598-021-90801-7
Autor:
Siwei Zhang, Melanie Ulrich, Elisa Schmoeckel, Doris Mayr, Angelika M. Vollmar, Melanie M Mandl, Johanna Liebl
Publikováno v:
British Journal of Cancer
Background: Tumour-initiating cells (TICs) account for chemoresistance, tumour recurrence and metastasis, and therefore represent a major problem in tumour therapy. However, strategies to address TICs are limited. Recent studies indicate Cdk5 as a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb7841e9a2a6dceb2afeff66f2a5eab
http://europepmc.org/articles/PMC5379151
http://europepmc.org/articles/PMC5379151
Autor:
Thomas F. Gronauer, Stephan A. Sieber, Markus Lakemeyer, Mathias W. Hackl, Johanna Pachmayr, Vadim S. Korotkov, Martina Meßner, Melanie M Mandl
Publikováno v:
Chemical communications (Cambridge, England). 54(70)
Human caseinolytic protease P (hClpP) is important for degradation of misfolded proteins in the mitochondrial unfolded protein response. We here introduce tailored hClpP inhibitors that utilize a steric discrimination in their core naphthofuran scaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadbce2d8f7afaeb09393f41b88b679c
https://pubmed.ncbi.nlm.nih.gov/30109319
https://pubmed.ncbi.nlm.nih.gov/30109319