Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Melanie M. Ivancic"'
Supplemental Methods and Figures. ROC Supplemental Methods. Supplemental Figure 1- microarray transcripts selected but whose gene products are not visible by proteomics. Supplemental Figure 2- ROC curves for individual biomarker candidates. Supplemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae08cf7f40fd06c2577b0e2c5160cae
https://doi.org/10.1158/1940-6207.22524821.v1
https://doi.org/10.1158/1940-6207.22524821.v1
Autor:
Michael R. Sussman, Perry J. Pickhardt, Yuriy Sverchkov, Melanie M. Ivancic, Mark Craven, Mark Reichelderfer, Gregory D. Kennedy, Bryant Megna
Publikováno v:
J Surg Res
Background A major roadblock to reducing the mortality of colorectal cancer (CRC) is prompt detection and treatment, and a simple blood test is likely to have higher compliance than all of the current methods. The purpose of this report is to examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d93ff63f0d682123c8bc7915d1bcd5
https://doi.org/10.1016/j.jss.2019.08.004
https://doi.org/10.1016/j.jss.2019.08.004
Autor:
Perry J. Pickhardt, Bryan D. Pooler, Michael R. Sussman, Linda Clipson, Melanie M. Ivancic, William F. Dove, Bryant Megna, Leigh W. Anson, Mark Reichelderfer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The premalignant colonic adenoma presents a long-lived target to prevent colon cancer. The levels of peptide biomarkers for four serum proteins—F5, ITIH4, LRG1, and VTN—are each elevated in sera in two adenoma-bearing animal models a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803d1820f3e6f081b7867f5c9a8bc125
http://europepmc.org/articles/PMC6486772
http://europepmc.org/articles/PMC6486772
Publikováno v:
Cancer Prevention Research. 7:1160-1169
The development of noninvasive methods for early detection of colon cancer is critical for the successful management of this disease. Using a targeted quantitative proteomics technique, we assessed the ability of 12 serum proteins to detect the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa3d36a0b5e86e17dab48941750b285
https://doi.org/10.1158/1940-6207.capr-14-0056
https://doi.org/10.1158/1940-6207.capr-14-0056
Autor:
Wan Jung Lin, Lakshmi Rajagopal, Melanie M. Ivancic, Aurelio Silvestroni, Kelsea A. Jewell, W. Andy Tao, James E. Connelly
Publikováno v:
Journal of Proteome Research. 8:2563-2574
All living organisms respond to changes in their internal and external environment for their survival and existence. Signaling is primarily achieved through reversible phosphorylation of proteins in both prokaryotes and eukaryotes. A change in the ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab4b4022103e5524046c7d540393c3a
https://doi.org/10.1021/pr900069n
https://doi.org/10.1021/pr900069n
Autor:
Melanie M. Ivancic, Alexey Eroshkin, Eric Wildfang, Guy S. Salvesen, Mari Enoksson, W. Andy Tao, Jingwei Li, John C. Timmer
Publikováno v:
Journal of Proteome Research. 6:2850-2858
The identification of natural substrates and their cleavage sites is pivotal to defining proteolytic pathways. Here we report a novel strategy for the identification of the signature of proteolytic cleavage events based on quantitative proteomics. Ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99caeedb16258e17a2909c284668541
https://doi.org/10.1021/pr0701052
https://doi.org/10.1021/pr0701052
Autor:
William F. Dove, Michael R. Sussman, Adrian D. Hegeman, Jennifer K. Pleiman, Melanie M. Ivancic, Xiaodi Chen, Amy A. Irving, Edward L. Huttlin
Current screening procedures for colorectal cancer are imperfect and highly invasive and result in increased mortality rates due to low compliance. The goal of the experiments reported herein is to identify potential blood-based biomarkers indicative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a4e8ef67d07910539d8671225c7746
https://europepmc.org/articles/PMC3792563/
https://europepmc.org/articles/PMC3792563/
Publikováno v:
Analytical biochemistry. 400(1)
The site-specific characterization of the complex glycans in multiglycosylated proteins requires developing methods where the carbohydrates remain covalently bound to the protein. The complexity in the carbohydrate composition of α1-acid glycoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2811c92d54428786bac886aa4e16c3ee
https://pubmed.ncbi.nlm.nih.gov/20100450
https://pubmed.ncbi.nlm.nih.gov/20100450
Autor:
Aurelio Silvestroni, Kelsea A. Jewell, Wan-Jung Lin, James E. Connelly, Melanie M. Ivancic, W. Andy Tao, Lakshmi Rajagopal
Publikováno v:
Journal of Proteome Research; May2009, Vol. 8 Issue 5, p2563-2574, 12p
Autor:
Mari Enoksson, Jingwei Li, Melanie M. Ivancic, John C. Timmer, Eric Wildfang, Alexey Eroshkin, Guy S. Salvesen, W. Andy Tao
Publikováno v:
Journal of Proteome Research; Jul2007, Vol. 6 Issue 7, p2850-2858, 9p