Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Melanie Müller"'
Autor:
Alena Reguzova, Melanie Müller, Felix Pagallies, Dominique Burri, Ferdinand Salomon, Hanns-Joachim Rziha, Zsofia Bittner-Schrader, Babs E. Verstrepen, Kinga P. Böszörményi, Ernst J. Verschoor, Ingo Gerhauser, Knut Elbers, Meral Esen, Alessandro Manenti, Martina Monti, Hans-Georg Rammensee, Madiha Derouazi, Markus W. Löffler, Ralf Amann
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Among the common strategies to design next-generation COVID-19 vaccines is broadening the antigenic repertoire thereby aiming to increase efficacy against emerging variants of concern (VoC). This study describes a new Orf virus-based vector
Externí odkaz:
https://doaj.org/article/527767ac247545008bac020a4f309146
Publikováno v:
Vaccines, Vol 12, Iss 5, p 492 (2024)
Viral vector vaccines represent a substantial advancement in immunization technology, offering numerous benefits over traditional vaccine modalities. The Orf virus (ORFV) strain D1701-VrV is a particularly promising candidate for vaccine development
Externí odkaz:
https://doaj.org/article/af87c64799c146449d4691c0ee27eaaa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundOrf virus (ORFV)-based vectors are attractive for vaccine development as they enable the induction of potent immune responses against specific transgenes. Nevertheless, the precise mechanisms of immune activation remain unknown. This study
Externí odkaz:
https://doaj.org/article/8c0857fdd2ef4c57b279ed84695e51ca
Autor:
Sabrina Schroeder, Sebastian J. Hofer, Andreas Zimmermann, Raimund Pechlaner, Christopher Dammbrueck, Tobias Pendl, G. Mark Marcello, Viktoria Pogatschnigg, Martina Bergmann, Melanie Müller, Verena Gschiel, Selena Ristic, Jelena Tadic, Keiko Iwata, Gesa Richter, Aitak Farzi, Muammer Üçal, Ute Schäfer, Michael Poglitsch, Philipp Royer, Ronald Mekis, Marlene Agreiter, Regine C. Tölle, Péter Sótonyi, Johann Willeit, Barbara Mairhofer, Helga Niederkofler, Irmgard Pallhuber, Gregorio Rungger, Herbert Tilg, Michaela Defrancesco, Josef Marksteiner, Frank Sinner, Christoph Magnes, Thomas R. Pieber, Peter Holzer, Guido Kroemer, Didac Carmona-Gutierrez, Luca Scorrano, Jörn Dengjel, Tobias Madl, Simon Sedej, Stephan J. Sigrist, Bence Rácz, Stefan Kiechl, Tobias Eisenberg, Frank Madeo
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108985- (2021)
Summary: Decreased cognitive performance is a hallmark of brain aging, but the underlying mechanisms and potential therapeutic avenues remain poorly understood. Recent studies have revealed health-protective and lifespan-extending effects of dietary
Externí odkaz:
https://doaj.org/article/39e2c2e4dbb64f9d873d1cd5180f9ef8
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1862 (2021)
Although dengue virus (DENV) affects almost half of the world’s population there are neither preventive treatments nor any long-lasting and protective vaccines available at this time. The complexity of the protective immune response to DENV is stil
Externí odkaz:
https://doaj.org/article/bc1077f98e874e86ba88994b2e4e22fb
Autor:
Eva M. Schleicher, Frederik W. Ott, Melanie Müller, Barbara Silcher, Marius E. Sichler, Maximilian J. Löw, Jannek M. Wagner, Yvonne Bouter
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
The Cannabis plant contains more than 100 currently known phytocannabinoids. Regarding the rising consumption of the non-psychotropic phytocannabinoid cannabidiol (CBD) in people’s everyday life (e.g., beauty products, food and beverages), the impo
Externí odkaz:
https://doaj.org/article/c161877218564515b9e3efd6cb70fd9b
Publikováno v:
Vaccines, Vol 8, Iss 2, p 295 (2020)
The potency of viral vector-based vaccines depends on their ability to induce strong transgene-specific immune response without triggering anti-vector immunity. Previously, Orf virus (ORFV, Parapoxvirus) strain D1701-V was reported as a novel vector
Externí odkaz:
https://doaj.org/article/350ef68a2132471096024fe622747f25
Autor:
Hanns-Joachim Rziha, Mathias Büttner, Melanie Müller, Ferdinand Salomon, Alena Reguzova, Dominic Laible, Ralf Amann
Publikováno v:
Viruses, Vol 11, Iss 2, p 127 (2019)
The Orf virus (ORFV; Parapoxvirus) strain D1701 with an attenuated phenotype and excellent immunogenic capacity is successfully used for the generation of recombinant vaccines against different viral infections. Adaption for growth in Vero cells was
Externí odkaz:
https://doaj.org/article/5246269d5a0f4eb780f409d05d0d8a60
Autor:
Maximilian G Posch, Stephan Waldmuller, Melanie Müller, Thomas Scheffold, David Fournier, Miguel A Andrade-Navarro, Bernard De Geeter, Sophie Guillaumont, Claire Dauphin, Dany Yousseff, Katharina R Schmitt, Andreas Perrot, Felix Berger, Roland Hetzer, Patrice Bouvagnet, Cemil Özcelik
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28872 (2011)
Secundum-type atrial septal defects (ASDII) account for approximately 10% of all congenital heart defects (CHD) and are associated with a familial risk. Mutations in transcription factors represent a genetic source for ASDII. Yet, little is known abo
Externí odkaz:
https://doaj.org/article/6cca99b082bb4c9ea87710d8b07682ce
Autor:
Birgit S Budde, Priska Binner, Stephan Waldmüller, Wolfgang Höhne, Wulf Blankenfeldt, Sabine Hassfeld, Jürgen Brömsen, Anastassia Dermintzoglou, Marcus Wieczorek, Erik May, Elisabeth Kirst, Carmen Selignow, Kirsten Rackebrandt, Melanie Müller, Roger S Goody, Hans-Peter Vosberg, Peter Nürnberg, Thomas Scheffold
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1362 (2007)
Noncompaction of the ventricular myocardium (NVM) is the morphological hallmark of a rare familial or sporadic unclassified heart disease of heterogeneous origin. NVM results presumably from a congenital developmental error and has been traced back t
Externí odkaz:
https://doaj.org/article/aea1aa68f40a4223bf737555eeecb32d