Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Melanie M, Pina"'
Autor:
Lara S Hwa, Sofia Neira, Meghan E Flanigan, Christina M Stanhope, Melanie M Pina, Dipanwita Pati, Olivia J Hon, Waylin Yu, Emily Kokush, Rachel Calloway, Kristen Boyt, Thomas L Kash
Publikováno v:
eLife, Vol 10 (2021)
Externí odkaz:
https://doaj.org/article/2c0796aba3494937bed38454bf92b203
Autor:
Lara S Hwa, Sofia Neira, Meghan E Flanigan, Christina M Stanhope, Melanie M Pina, Dipanwita Pati, Olivia J Hon, Waylin Yu, Emily Kokush, Rachel Calloway, Kristen Boyt, Thomas L Kash
Publikováno v:
eLife, Vol 9 (2020)
Maladaptive responses to stress are a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized. Here, we show that kappa opioid receptor signaling in the bed nucleus of the stria terminalis (BNST) is a critic
Externí odkaz:
https://doaj.org/article/4104ba0a03f344c28e976ea14ee11ef8
Autor:
Melanie M. Pina, Dipanwita Pati, Sofia Neira, Lisa R. Taxier, Christina M. Stanhope, Alexandra A. Mahoney, Shannon D’Ambrosio, Thomas L. Kash, Montserrat Navarro
Publikováno v:
The Journal of Neuroscience. :JN-RM
Alcohol use disorder is complex and multi-faceted, involving the coordination of multiple signaling systems across numerous brain regions. Previous work has indicated that both the insular cortex and dynorphin (DYN)/Kappa opioid receptor (KOR) system
Autor:
Kristen M. Boyt, Dipanwita Pati, Melanie M. Pina, Sofia Neira, Waylin Yu, Lara S. Hwa, Emily Kokush, Meghan E. Flanigan, Rachel Calloway, Olivia J Hon, Thomas L. Kash, Christina M. Stanhope
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Maladaptive responses to stress are a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized. Here, we show that kappa opioid receptor signaling in the bed nucleus of the stria terminalis (BNST) is a critic
Publikováno v:
Neuropsychopharmacology. 44:1843-1854
Contextual cues associated with drugs of abuse, such as ethanol, can trigger craving and drug seeking behavior. Pavlovian procedures, such as place conditioning, have been widely used to study the rewarding/aversive properties of drugs and the associ
Autor:
Dipanwita Pati, Avery C. Hunker, Karl T. Schmidt, Kristen M. Boyt, Zoe A. McElligott, Larry S. Zweifel, Thomas L. Kash, Waylin Yu, Melanie M. Pina
Publikováno v:
Neuron
Sex differences in pain severity, response, and pathological susceptibility are widely reported, but the neural mechanisms that contribute to these outcomes remain poorly understood. Here we show that dopamine (DA) neurons in the ventrolateral periaq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec5451852f4bfe387f6d3aaf55d021e
https://europepmc.org/articles/PMC9990825/
https://europepmc.org/articles/PMC9990825/
Autor:
Lara S Hwa, Sofia Neira, Meghan E Flanigan, Christina M Stanhope, Melanie M Pina, Dipanwita Pati, Olivia J Hon, Waylin Yu, Emily Kokush, Rachel Calloway, Kristen Boyt, Thomas L Kash
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cab266c1e13d4f3f589f931dfad7733
https://doi.org/10.7554/elife.59709.sa2
https://doi.org/10.7554/elife.59709.sa2
Autor:
Rachel Calloway, Emily Kokush, Melanie M. Pina, Christina M. Stanhope, Lara S. Hwa, Dipanwita Pati, Meghan E. Flanigan, Thomas L. Kash, Sofia Neira, Waylin Yu, Kristen M. Boyt, Olivia J Hon
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Maladaptive responses to stress are a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized. Here, we show that kappa opioid receptor signaling in the bed nucleus of the stria terminalis (BNST) is a critic
Publikováno v:
Neuropsychopharmacology. 44:766-775
Acute exposure to a salient stressor, such as in post-traumatic stress disorder, can have lasting impacts upon an individual and society. To study stress in rodents, some naturalistic methods have included acute exposure to a predator odor, such as t
Autor:
Patrick M. Sexton, Elham Khajehali, Reid H.J. Olsen, Kristen M. Boyt, Karen J. Thompson, Samuel T. Slocum, Andrew B. Tobin, Colin Molloy, Melanie M. Pina, Christoffer Bundgaard, Michael J. Krashes, Bryan L. Roth, Xi Ping Huang, Arthur Christopoulos, Jeffrey F. DiBerto, Sophie J. Bradley, Jovana Navarrete, Thomas L. Kash, Yan Xiong, Jing Liu, Dipanwita Pati, Jian Jin
Publikováno v:
ACS Pharmacology & Translational Science. 1:61-72
Chemogenetic tools such as designer receptors exclusively activated by designer drugs (DREADDs) are routinely used to modulate neuronal and non-neuronal signaling and activity in a relatively noninvasive manner. The first generation of DREADDs were t