Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Melanie Loth"'
Autor:
Kim-Anh Lê Cao, Al J. Abadi, Emily F. Davis-Marcisak, Lauren Hsu, Arshi Arora, Alexis Coullomb, Atul Deshpande, Yuzhou Feng, Pratheepa Jeganathan, Melanie Loth, Chen Meng, Wancen Mu, Vera Pancaldi, Kris Sankaran, Amrit Singh, Joshua S. Sodicoff, Genevieve L. Stein-O’Brien, Ayshwarya Subramanian, Joshua D. Welch, Yue You, Ricard Argelaguet, Vincent J. Carey, Ruben Dries, Casey S. Greene, Susan Holmes, Michael I. Love, Matthew E. Ritchie, Guo-Cheng Yuan, Aedin C. Culhane, Elana Fertig
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Externí odkaz:
https://doaj.org/article/49dce808426c4beba2bce0c0ce894bf9
Autor:
Shangzi Wang, Elana J Fertig, Allison A Fitzgerald, Veena Agarwal, Emily F Marcisak, Annie Zuo, Sandra A Jablonski, Melanie Loth, John MacDougall, Eugene Zhukovsky, Shubhendu Trivedi, Dimple Bhatia, Vince O'Neill, Louis M Weiner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/0ee773f945a04c99afce61314f31fcd8
Autor:
Kim-Anh Lê Cao, Al J. Abadi, Emily F. Davis-Marcisak, Lauren Hsu, Arshi Arora, Alexis Coullomb, Atul Deshpande, Yuzhou Feng, Pratheepa Jeganathan, Melanie Loth, Chen Meng, Wancen Mu, Vera Pancaldi, Kris Sankaran, Dario Righelli, Amrit Singh, Joshua S. Sodicoff, Genevieve L. Stein-O’Brien, Ayshwarya Subramanian, Joshua D. Welch, Yue You, Ricard Argelaguet, Vincent J. Carey, Ruben Dries, Casey S. Greene, Susan Holmes, Michael I. Love, Matthew E. Ritchie, Guo-Cheng Yuan, Aedin C. Culhane, Elana Fertig
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5c9dfac685c74ac0add83eb9f681b88f
Autor:
Eloïse M. Grasset, Matthew Dunworth, Gaurav Sharma, Melanie Loth, Joseph Tandurella, Ashley Cimino-Mathews, Melissa Gentz, Sydney Bracht, Meagan Haynes, Elana J. Fertig, Andrew J. Ewald
Publikováno v:
Sci Transl Med
Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early metastatic recurrence and worse patient outcomes. TNBC tumors express molecular markers of the epithelial-mesenchymal transition (EMT), but its requirement during spo
Autor:
Benedict Kinny-Köster, Samantha Guinn, Joseph A. Tandurella, Jacob T. Mitchell, Dimitrios N. Sidiropoulos, Melanie Loth, Melissa R. Lyman, Alexandra B. Pucsek, Toni T. Seppälä, Christopher Cherry, Reecha Suri, Haley Zlomke, Jin He, Christopher L. Wolfgang, Jun Yu, Lei Zheng, David P. Ryan, David T. Ting, Alec Kimmelman, Anuj Gupta, Ludmila Danilova, Jennifer H. Elisseeff, Laura D. Wood, Genevieve Stein-O’Brien, Luciane T. Kagohara, Elizabeth M. Jaffee, Richard A. Burkhart, Elana J. Fertig, Jacquelyn W. Zimmerman
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by a heterogeneous tumor microenvironment (TME) that is enriched with cancer associated fibroblasts (CAFs)1. Cell-cell interactions involving these CAFs promote an immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cc5107abd96598f6c594da5251e9ad2
https://doi.org/10.1101/2022.07.14.500096
https://doi.org/10.1101/2022.07.14.500096
Autor:
Jeanette Johnson, Ashley Tsang, Jacob T. Mitchell, Emily Davis-Marcisak, Thomas Sherman, Ted Liefeld, Melanie Loth, Loyal A Goff, Jacquelyn Zimmerman, Ben Kinny-Köster, Elizabeth Jaffee, Pablo Tamayo, Jill P. Mesirov, Michael Reich, Elana J. Fertig, Genevieve L. Stein-O’Brien
Non-negative matrix factorization (NMF) is an unsupervised learning method well suited to high-throughput biology. Still, inferring biological processes requires additional post hoc statistics and annotation for interpretation of features learned fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fddaa2fcfa5da5d1a5a2901c059ebcba
https://doi.org/10.1101/2022.07.09.499398
https://doi.org/10.1101/2022.07.09.499398
Autor:
Atul Deshpande, Melanie Loth, Dimitrios N. Sidiropoulos, Shuming Zhang, Long Yuan, Alexander Bell, Qingfeng Zhu, Won Jin Ho, Cesar Santa-Maria, Daniele Gilkes, Stephen R. Williams, Cedric R. Uytingco, Jennifer Chew, Andrej Hartnett, Zachary W. Bent, Alexander V. Favorov, Aleksander S. Popel, Mark Yarchoan, Lei Zheng, Elizabeth M. Jaffee, Robert Anders, Ludmila Danilova, Genevieve Stein-O’Brien, Luciane T. Kagohara, Elana J. Fertig
Recent advances in spatial transcriptomics (ST) enable gene expression measurements from a tissue sample while retaining its spatial context. This technology enables unprecedented in situ resolution of the regulatory pathways that underlie the hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8539ecb4627b27e393d2efa1eed6adf
https://doi.org/10.1101/2022.06.02.490672
https://doi.org/10.1101/2022.06.02.490672
Autor:
Joseph A. Tandurella, Jacob T. Mitchell, Janelle M. Montagne, Eric Christenson, Qingfeng Zhu, Ludmilla V. Danilova, Alexander V. Favorov, Won J. Ho, Luciane T. Kagohara, Melanie Loth, Su Jin Lim, Rui Zheng, Jessica Gai, Sarah Mitchell, Dimitrios N. Sidiropoulos, Wenpin Hou, Yao Xu, Hao Wang, Jacquelyn W. Zimmerman, Srinivasan Yegnasubramanian, Robert Anders, Elizabeth M. Jaffee, Lei Zheng, Elana J. Fertig
Publikováno v:
Cancer Research. 83:3241-3241
Introduction: Pancreatic ductal adenocarcinomas (PDACs) are immunogenically “cold” tumors that lack effector T cell infiltration associated with immune checkpoint inhibitor (ICI) responsiveness. Neoadjuvant immunotherapy clinical trials facilitat
Autor:
Atul Deshpande, Melanie Loth, Dimitrios N. Sidiropoulos, Shuming Zhang, Long Yuan, Alexander T.F. Bell, Qingfeng Zhu, Won Jin Ho, Cesar Santa-Maria, Daniele M. Gilkes, Stephen R. Williams, Cedric R. Uytingco, Jennifer Chew, Andrej Hartnett, Zachary W. Bent, Alexander V. Favorov, Aleksander S. Popel, Mark Yarchoan, Ashley Kiemen, Pei-Hsun Wu, Kohei Fujikura, Denis Wirtz, Laura D. Wood, Lei Zheng, Elizabeth M. Jaffee, Robert A. Anders, Ludmila Danilova, Genevieve Stein-O’Brien, Luciane T. Kagohara, Elana J. Fertig
Publikováno v:
Cell Systems. 14:285-301.e4
Autor:
Atul Deshpande, Melanie Loth, Dimitrios Sidiropoulos, QingFeng Zhu, Genevieve Stein-O'Brien, NIkhil Rao, Cedric Uytingco, Stephen Williams, Cesar Santa-Maria, Daniele M. Gilkes, Lei Zhang, Elizabeth Jaffee, Robert Anders, Ludmila Danilova, Luciane T. Kagohara, Elana J. Fertig
Publikováno v:
Cancer Research. 82:2130-2130
Recent advances in spatial transcriptomics (ST) enable us to measure gene expression from cancer tissues while retaining their spatial context. We present a novel bioinformatics pipeline to infer molecular changes from tumor and immune cell interacti