Synthesis of new 8(S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors

Autor: Erwan Ayral, Pierre Renard, Jean A. Boutin, Paul Mosset, Alain Ktorza, René Grée, Frédéric Caijo, Catherine Dacquet, Anne-Lise Girard, Valérie Audinot, Melanie Liutkus, Daniel H. Caignard

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Informa Healthcare, 2010, 25 (5), pp.653-72. ⟨10.3109/14756360903468171⟩
Journal of Enzyme Inhibition and Medicinal Chemistry, 2010, 25 (5), pp.653-72. ⟨10.3109/14756360903468171⟩

Structural modifications around 8-HETE (8-hydroxyeicosatetraenoic acid), a natural agonist of the PPAR (peroxisome proliferator-activated receptor) nuclear receptors have led previously to the identification of a promising analog, the quinoline S 706

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4bdbf3d3d5d3d2c0f5e73c1a47da28
https://pubmed.ncbi.nlm.nih.gov/20518620