Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

Autor: Guy M. Goodwin, Scott T. Aaronson, Oscar Alvarez, Peter C. Arden, Annie Baker, James C. Bennett, Catherine Bird, Renske E. Blom, Christine Brennan, Donna Brusch, Lisa Burke, Kete Campbell-Coker, Robin Carhart-Harris, Joseph Cattell, Aster Daniel, Charles DeBattista, Boadie W. Dunlop, Katherine Eisen, David Feifel, MacKenzie Forbes, Hannah M. Haumann, David J. Hellerstein, Astrid I. Hoppe, Muhammad I. Husain, Luke A. Jelen, Jeanine Kamphuis, Julie Kawasaki, John R. Kelly, Richard E. Key, Ronit Kishon, Stephanie Knatz Peck, Gemma Knight, Martijn H.B. Koolen, Melanie Lean, Rasmus W. Licht, Jessica L. Maples-Keller, Jan Mars, Lindsey Marwood, Martin C. McElhiney, Tammy L. Miller, Arvin Mirow, Sunil Mistry, Tanja Mletzko-Crowe, Liam N. Modlin, René E. Nielsen, Elizabeth M. Nielson, Sjoerd R. Offerhaus, Veronica O’Keane, Tomáš Páleníček, David Printz, Marleen C. Rademaker, Aumer van Reemst, Frederick Reinholdt, Dimitris Repantis, James Rucker, Samuel Rudow, Simon Ruffell, A. John Rush, Robert A. Schoevers, Mathieu Seynaeve, Samantha Shao, Jair C. Soares, Metten Somers, Susan C. Stansfield, Diane Sterling, Aaron Strockis, Joyce Tsai, Lucy Visser, Mourad Wahba, Samuel Williams, Allan H. Young, Paula Ywema, Sidney Zisook, Ekaterina Malievskaia

Publikováno v: Goodwin, G M, Aaronson, S T, Alvarez, O, Arden, P C, Baker, A, Bennett, J C, Bird, C, Blom, R E, Brennan, C, Brusch, D, Burke, L, Campbell-Coker, K, Carhart-Harris, R, Cattell, J, Daniel, A, DeBattista, C, Dunlop, B W, Eisen, K, Feifel, D, Forbes, M, Haumann, H M, Hellerstein, D J, Hoppe, A I, Husain, M I, Jelen, L A, Kamphuis, J, Kawasaki, J, Kelly, J R, Key, R E, Kishon, R, Knatz Peck, S, Knight, G, Koolen, M H B, Lean, M, Licht, R W, Maples-Keller, J L, Mars, J, Marwood, L, McElhiney, M C, Miller, T L, Mirow, A, Mistry, S, Mletzko-Crowe, T, Modlin, L N, Nielsen, R E, Nielson, E M, Offerhaus, S R, O’Keane, V, Páleníček, T, Printz, D, Rademaker, M C, van Reemst, A, Reinholdt, F, Repantis, D, Rucker, J, Rudow, S, Ruffell, S, Rush, A J, Schoevers, R A, Seynaeve, M, Shao, S, Soares, J C, Somers, M, Stansfield, S C, Sterling, D, Strockis, A, Tsai, J, Visser, L, Wahba, M, Williams, S, Young, A H, Ywema, P, Zisook, S & Malievskaia, E 2022, ' Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression ', New England Journal of Medicine, vol. 387, no. 18, pp. 1637-1648 . https://doi.org/10.1056/NEJMoa2206443
The New England journal of medicine, 387(18), 1637-1648. MASSACHUSETTS MEDICAL SOC
Goodwin, G M, Aaronson, S T, Alvarez, O, Arden, P C, Baker, A, Bennett, J C, Bird, C, Blom, R E, Brennan, C, Brusch, D, Burke, L, Campbell-Coker, K, Carhart-Harris, R, Cattell, J, Daniel, A, DeBattista, C, Dunlop, B W, Eisen, K, Feifel, D, Forbes, M, Haumann, H M, Hellerstein, D J, Hoppe, A I, Husain, M I, Jelen, L A, Kamphuis, J, Kawasaki, J, Kelly, J R, Key, R E, Kishon, R, Knatz Peck, S, Knight, G, Koolen, M H B, Lean, M, Licht, R W, Maples-Keller, J L, Mars, J, Marwood, L, McElhiney, M C, Miller, T L, Mirow, A, Mistry, S, Mletzko-Crowe, T, Modlin, L N, Nielsen, R E, Nielson, E M, Offerhaus, S R, O'Keane, V, Páleníček, T, Printz, D, Rademaker, M C, van Reemst, A, Reinholdt, F, Repantis, D, Rucker, J, Rudow, S, Ruffell, S, Rush, A J, Schoevers, R A, Seynaeve, M, Shao, S, Soares, J C, Somers, M, Stansfield, S C, Sterling, D, Strockis, A, Tsai, J, Visser, L, Wahba, M, Williams, S, Young, A H, Ywema, P, Zisook, S & Malievskaia, E 2022, ' Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression. ', The New England Journal of Medicine, vol. 387, no. 18, pp. 1637-1648 . https://doi.org/10.1056/NEJMoa2206443

BACKGROUND: Psilocybin is being studied for use in treatment-resistant depression.METHODS: In this phase 2 double-blind trial, we randomly assigned adults with treatment-resistant depression to receive a single dose of a proprietary, synthetic formul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b8742fc702d2c23f77f5222cb3a4d0
https://doi.org/10.1056/nejmoa2206443

The Rehabilitation Effectiveness for Activities for Life (REAL) study: a national programme of research into NHS inpatient mental health rehabilitation services across England

Autor: Helen Killaspy, Michael King, Frank Holloway, Thomas J Craig, Sarah Cook, Tim Mundy, Gerard Leavey, Paul McCrone, Leonardo Koeser, Rumana Omar, Louise Marston, Maurice Arbuthnott, Nicholas Green, Isobel Harrison, Melanie Lean, Melanie Gee, Sadiq Bhanbhro

Publikováno v: Programme Grants for Applied Research, Vol 5, Iss 7 (2017)

Background: The REAL (Rehabilitation Effectiveness for Activities for Life) research programme, funded by the National Institute for Heath Research (NIHR) from 2009 to 2015, investigated NHS mental health rehabiliation services across England. The us

Externí odkaz: https://doaj.org/article/06b86c1c1e584bdc8d7a01f13ad7c3ae

Crisis resolution teams for people experiencing mental health crises: the CORE mixed-methods research programme including two RCTs

Autor: Tom Mundy, Hannah Istead, Liberty Mosse, Claire Wheeler, Puffin O’Hanlon, David Hindle, Melanie Lean, Louise Marston, Alyssa Milton, Sarah A Sullivan, Sarah Fahmy, Rebecca Forsyth, Stephen Pilling, Fiona Nolan, Nicky Goater, Alasdair Churchard, Gareth Ambler, Beth Paterson, Michael Davidson, Oliver Mason, Marina Christoforou, Sonia Johnson, Emma Burgess, Monica Leverton, Claire Henderson, Nicola Morant, Danielle Lamb, Edward Mundy, David Osborn, Brynmor Lloyd-Evans, Kathleen Kelly, Ellie Brown, Tim Weaver, Kate Fullarton, Richard Gray, Elaine Johnston, Jonathan Piotrowski, Rachael Hunter

Publikováno v: Programme Grants for Applied Research, Vol 7, Iss 1 (2019)

Background Crisis resolution teams (CRTs) seek to avert hospital admissions by providing intensive home treatment for people experiencing a mental health crisis. The CRT model has not been highly specified. CRT care is often experienced as ending abr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f294c1cb77d42380777be6e965f4918
https://doi.org/10.3310/pgfar07010

Pilot study of a group worry intervention for recent onset psychosis

Autor: Melanie Lean, Kate V. Hardy, Teal Mackintosh

Publikováno v: The Cognitive Behaviour Therapist. 14

Worry is common among individuals with psychosis and has been found to be a causal factor in the development of paranoia. Previous research has shown that a cognitive behavioural therapy protocol targeting worry helps to reduce persecutory delusions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4fcdd2116ab3fd8b70e1ce4d9b945ec
https://doi.org/10.1017/s1754470x21000106

The Rehabilitation Effectiveness for Activities for Life (REAL) study: a national programme of research into NHS inpatient mental health rehabilitation services across England

Autor: Nicholas Green, Melanie Gee, Louise Marston, Paul McCrone, Timothy Mundy, Isobel Harrison, Melanie Lean, Sadiq Bhanbhro, Gerard Leavey, Frank Holloway, Tom K. J. Craig, Leonardo Koeser, Sarah Cook, Rumana Z Omar, Maurice Arbuthnott, Helen Killaspy, Michael King

Publikováno v: Programme Grants for Applied Research, Vol 5, Iss 7 (2017)

BackgroundThe REAL (Rehabilitation Effectiveness for Activities for Life) research programme, funded by the National Institute for Heath Research (NIHR) from 2009 to 2015, investigated NHS mental health rehabiliation services across England. The user

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb80174130771ff1bfc9e93bf5a4630
https://doi.org/10.3310/pgfar05070