Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Melanie L. Hart"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ae56a40c2b6b4feb8483cb98c5bf0259
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionThe last decade has led to rapid developments and increased usage of computational tools at the single-cell level. However, our knowledge remains limited in how extracellular cues alter quantitative macrophage morphology and how such morp
Externí odkaz:
https://doaj.org/article/60a068992edc4864a78e30c27d7a520a
Autor:
Hermann O. Mayr, Nina Regenbrecht, Moritz Florian Mayr, Bianca Riedel, Melanie L. Hart, Hagen Schmal, Michael Seidenstuecker
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3143 (2023)
Background: The treatment of grafts with vancomycin for ligament reconstruction in knee surgery is the current standard. However, high antibiotic concentrations have chondrotoxic effects. Purpose: To test the chondrotoxicity of clindamycin, gentamici
Externí odkaz:
https://doaj.org/article/b925cb26a7cb4f75a15eef8e0c7d7a38
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionLittle is known how inflammatory processes quantitatively affect chondrocyte morphology and how single cell morphometric data could be used as a biological fingerprint of phenotype.MethodsWe investigated whether trainable high-throughput
Externí odkaz:
https://doaj.org/article/769bb6ec9e1a4be4833c36b62aa3fc6f
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Many studies have elegantly shown that murine and rat bone marrow-derived mesenchymal stromal cells (bmMSCs) contribute to muscle regeneration and improve muscle function. Yet, the ability of transplanted human bmMSCs to manifest
Externí odkaz:
https://doaj.org/article/f3c090ed2f9c4f56a53a10a90528d328
Autor:
Jules A. Menima-Medzogo, Kathrin Walz, Jasmin C. Lauer, Gopakumar Sivasankarapillai, F. Robert Gleuwitz, Bernd Rolauffs, Marie-Pierre Laborie, Melanie L. Hart
Publikováno v:
Biology, Vol 11, Iss 5, p 696 (2022)
There is limited data assessing the cytotoxic effects of organosolv lignin with cells commonly used in tissue engineering. Structural and physico-chemical characterization of fractionated organosolv lignin showed that a decrease of the molecular weig
Externí odkaz:
https://doaj.org/article/a29a9c676ee542b0ba380c897d5b6165
Publikováno v:
Cells, Vol 10, Iss 11, p 3123 (2021)
Adipose-derived stem cells (ASCs) are an abundant and easily accessible multipotent stem cell source with potential application in smooth muscle regeneration strategies. In 3D collagen hydrogels, we investigated whether sustained release of growth fa
Externí odkaz:
https://doaj.org/article/04ac1f8d1d3446ceae49ec0940ec0f8a
Autor:
Brandan Walters, Tatiana Uynuk-Ool, Miriam Rothdiener, Julian Palm, Melanie L. Hart, Jan P. Stegemann, Bernd Rolauffs
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Stem cells have been predicted to improve disease outcomes and patient lives. Steering stem cell fate - through controlling cell shape - may substantially accelerate progress towards this goal. As mesenchymal stromal cells (MSCs) are continu
Externí odkaz:
https://doaj.org/article/300e8f51c90a4d3c98cf2320425ab844
Autor:
Bastian Amend, Martin Vaegler, Kerstin Fuchs, Julia G. Mannheim, Susanne Will, Ulrich Kramer, Melanie L. Hart, Wouter Feitz, Christopher Chapple, Arnulf Stenzl, Wilhelm K. Aicher
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Stress urinary incontinence (SUI) is a largely ousted but significant medical, social, and economic problem. Surveys suggest that nowadays approximately 10% of the male and 15% of the female population suffer from urinary incontinence at some stage i
Externí odkaz:
https://doaj.org/article/e700af744be44d6d9198c8d6ace271ba
Autor:
Melanie L. Hart, Jasmin C. Lauer, Mischa Selig, Martha Hanak, Brandan Walters, Bernd Rolauffs
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 3, Iss 1, p 2 (2017)
In a worldwide effort to generate clinically useful therapeutic or preventive interventions, harnessing biophysical stimuli for directing cell fate is a powerful strategy. With the vision to control cell function through engineering cell shape, bette
Externí odkaz:
https://doaj.org/article/241c115c15fd47d59a8b015069b8a4da