Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Melanie L Lehman"'
Autor:
Shirly Sieh, Anna V Taubenberger, Simone C Rizzi, Martin Sadowski, Melanie L Lehman, Anja Rockstroh, Jiyuan An, Judith A Clements, Colleen C Nelson, Dietmar W Hutmacher
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e40217 (2012)
Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in normal and cancer cells. Since two-dimensional (2D) cultures lack the essential characteristics
Externí odkaz:
https://doaj.org/article/3ae1c03cc7664588b81ef6f282d896d5
Autor:
Thomas Kryza, Nathalie Bock, Scott Lovell, Anja Rockstroh, Melanie L. Lehman, Adam Lesner, Janaththani Panchadsaram, Lakmali Munasinghage Silva, Srilakshmi Srinivasan, Cameron E. Snell, Elizabeth D. Williams, Ladan Fazli, Martin Gleave, Jyotsna Batra, Colleen Nelson, Edward W. Tate, Jonathan Harris, John D. Hooper, Judith A. Clements
Publikováno v:
Molecular Oncology, Vol 14, Iss 1, Pp 105-128 (2020)
Kallikrein‐related peptidase 14 (KLK14) is one of the several secreted KLK serine proteases involved in prostate cancer (PCa) pathogenesis. While relatively understudied, recent reports have identified KLK14 as overexpressed during PCa development.
Externí odkaz:
https://doaj.org/article/d544b520f038431180fefe9421c7d971
Autor:
John Lai, Leire Moya, Jiyuan An, Andrea Hoffman, Srilakshmi Srinivasan, Janaththani Panchadsaram, Carina Walpole, Joanna L. Perry-Keene, Suzanne Chambers, Australian Prostate Cancer BioResource, Melanie L. Lehman, Colleen C. Nelson, Judith A. Clements, Jyotsna Batra
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Short tandem repeats (STRs) are repetitive sequences of a polymorphic stretch of two to six nucleotides. We hypothesized that STRs are associated with prostate cancer development and/or progression. We undertook RNA sequencing analysis of pr
Externí odkaz:
https://doaj.org/article/5d9e5e6634f54987ae535d2c9dbf9217
Autor:
Phoebe L. Sarkar, Wendy Lee, Elizabeth D. Williams, Amy A. Lubik, Nataly Stylianou, Ali Shokoohmand, Melanie L. Lehman, Brett G. Hollier, Jennifer H. Gunter, Colleen C. Nelson
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer (PCa), yet many patients relapse with lethal metastatic disease. With this loss of androgens, increased cell plasticity has been observed as an adaptive respons
Externí odkaz:
https://doaj.org/article/698d511671a7433ebdb514ff6f6cc51c
Autor:
Martin C. Sadowski, Colleen C. Nelson, Marcel E. Dinger, Nenad Bartonicek, Lisa K. Philp, Stephen J. McPherson, Chenwei Wang, Melanie L. Lehman, Atefeh Taherian Fard, Anja Rockstroh, Kaylyn D. Tousignant
Figure S1: LNCaP, VCaP and DuCaP cells were grown in charcoal-dextran stripped serum (CSS) for 48 h and treated with increasing concentrations of R1881 or DHT in the presence or absence of Enzalutamide (10 µM) or vehicle (Ctrl) for 48 h. Figure S2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110d167333fec1a49913df2360f93a80
https://doi.org/10.1158/1541-7786.22513437.v1
https://doi.org/10.1158/1541-7786.22513437.v1
Autor:
Jeff Holst, John E.J. Rasko, Colleen C. Nelson, Grant Buchanan, Stephen C. Hendy, Melanie L. Lehman, Vineet Minhas, Annora Thoeng, Jessamy Tiffen, Cynthia Ng, Charles G. Bailey, Qian Wang
PDF file - 1.5K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5044669b4304c59017cd4d001a67230b
https://doi.org/10.1158/0008-5472.22389840
https://doi.org/10.1158/0008-5472.22389840
Autor:
Jeff Holst, John E.J. Rasko, Colleen C. Nelson, Grant Buchanan, Stephen C. Hendy, Melanie L. Lehman, Vineet Minhas, Annora Thoeng, Jessamy Tiffen, Cynthia Ng, Charles G. Bailey, Qian Wang
PDF file - 141K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00cf862b2b58318cd0667adcb2bdfd18
https://doi.org/10.1158/0008-5472.22389837.v1
https://doi.org/10.1158/0008-5472.22389837.v1
Autor:
Jeff Holst, John E.J. Rasko, Colleen C. Nelson, Grant Buchanan, Stephen C. Hendy, Melanie L. Lehman, Vineet Minhas, Annora Thoeng, Jessamy Tiffen, Cynthia Ng, Charles G. Bailey, Qian Wang
l-Type amino acid transporters such as LAT1 and LAT3 mediate the uptake of essential amino acids. Here, we report that prostate cancer cells coordinate the expression of LAT1 and LAT3 to maintain sufficient levels of leucine needed for mTORC1 signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b389a969a7fe1b2d31aebe508a4d9f
https://doi.org/10.1158/0008-5472.c.6502737.v1
https://doi.org/10.1158/0008-5472.c.6502737.v1
Autor:
Shirly Sieh, Anna V. Taubenberger, Simone C. Rizzi, Martin Sadowski, Melanie L. Lehman, Anja Rockstroh, Jiyuan An, Judith A. Clements, Colleen C. Nelson, Dietmar W. Hutmacher
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/381ee7dc539c439bb9ff97e05cab882f
Autor:
Shirly Sieh, Anna V. Taubenberger, Simone C. Rizzi, Martin Sadowski, Melanie L. Lehman, Anja Rockstroh, Jiyuan An, Judith A. Clements, Colleen C. Nelson, Dietmar W. Hutmacher
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1 (2013)
PLoS ONE, Vol 8, Iss 1 (2013)