Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melanie L, Johnston"'
Autor:
Alexander Shaver, J.D. Mahlum, Karen Scida, Melanie L. Johnston, Miguel Aller Pellitero, Yao Wu, Gregory V. Carr, Netzahualcóyotl Arroyo-Currás
Publikováno v:
ACS Sensors. 7:3895-3905
The measurement of serum vancomycin levels at the clinic is critical to optimizing dosing given the narrow therapeutic window of this antibiotic. Current approaches to quantitate serum vancomycin levels are based on immunoassays, which are multistep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829eee14061fca603896c233ff183f93
https://doi.org/10.1021/acssensors.2c01910
https://doi.org/10.1021/acssensors.2c01910
Publikováno v:
Biochemistry. 61:1810-1823
The bacterial enzyme 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) catalyzes the formation of DXP from pyruvate and d-glyceraldehyde 3-phosphate (d-GAP) in a thiamin diphosphate (ThDP)-dependent manner. In addition to its role in isoprenoid biosynth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbbcf7472159ba9d60221db1f55145f
https://doi.org/10.1021/acs.biochem.2c00274
https://doi.org/10.1021/acs.biochem.2c00274
Publikováno v:
Biochemistry. 60(12)
The thiamin diphosphate-dependent enzyme 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) catalyzes the formation of DXP from pyruvate (donor) and d-glyceraldehyde 3-phosphate (d-GAP, acceptor). DXPS is essential in bacteria but absent in human metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e8df951f147f72c4d7cc7c1bbc6343
https://pubmed.ncbi.nlm.nih.gov/33660509
https://pubmed.ncbi.nlm.nih.gov/33660509
Publikováno v:
Comprehensive Natural Products III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4786edc4e7ab66af8c8f8c9ae6823fdd
https://doi.org/10.1016/b978-0-12-409547-2.14710-9
https://doi.org/10.1016/b978-0-12-409547-2.14710-9
Autor:
Sakshi, Tomar, Melanie L, Johnston, Sarah E, St John, Heather L, Osswald, Prasanth R, Nyalapatla, Lake N, Paul, Arun K, Ghosh, Mark R, Denison, Andrew D, Mesecar
Publikováno v:
The Journal of biological chemistry. 290(32)
All coronaviruses, including the recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) from the β-CoV subgroup, require the proteolytic activity of the nsp5 protease (also known as 3C-like protease, 3CL(pro)) during virus replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99369935a66d3a4f5422d116b2060135
https://pubmed.ncbi.nlm.nih.gov/26055715
https://pubmed.ncbi.nlm.nih.gov/26055715