Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Melanie Kienzl"'
Autor:
Eva Gruden, Melanie Kienzl, Dusica Ristic, Oliver Kindler, David Markus Kaspret, Sophie Theresa Schmid, Julia Kargl, Eva Sturm, Alfred D. Doyle, Benjamin L. Wright, Franziska Baumann-Durchschein, Julia Konrad, Andreas Blesl, Hansjörg Schlager, Rudolf Schicho
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEosinophilic esophagitis (EoE) is a chronic, inflammatory, antigen-driven disease of the esophagus. Tissue EoE pathology has previously been extensively characterized by novel transcriptomics and proteomic platforms, however the majority
Externí odkaz:
https://doaj.org/article/81178be6e1fd4cbeacbd002673c765da
Autor:
Melanie Kienzl, Kathrin Maitz, Arailym Sarsembayeva, Paulina Valadez-Cosmes, Eva Gruden, Dusica Ristic, Karolina Herceg, Julia Kargl, Rudolf Schicho
Publikováno v:
Cancers, Vol 16, Iss 2, p 295 (2024)
The tumor microenvironment (TME) is pivotal in cancer progression and the response to immunotherapy. A “hot” tumor typically contains immune cells that promote anti-tumor immunity, predicting positive prognosis. “Cold” tumors lack immune cell
Externí odkaz:
https://doaj.org/article/e426005c51ad457e81021a5f12024567
Autor:
Kathrin Maitz, Paulina Valadez-Cosmes, Sofia Raftopoulou, Oliver Kindler, Melanie Kienzl, Hamid Bolouri, A. McGarry Houghton, Rudolf Schicho, Akos Heinemann, Julia Kargl
Publikováno v:
Cancers, Vol 15, Iss 24, p 5767 (2023)
Lung cancer is the leading cause of cancer-related death worldwide. Discoidin domain receptor 1 (DDR1), a tyrosine kinase receptor, has been associated with poor prognosis in patients with non-small cell lung cancer (NSCLC). However, its role in tumo
Externí odkaz:
https://doaj.org/article/341ac169d8cf4519aab8942249400edd
Autor:
Arailym Sarsembayeva, Melanie Kienzl, Eva Gruden, Dusica Ristic, Kathrin Maitz, Paulina Valadez-Cosmes, Ana Santiso, Carina Hasenoehrl, Luka Brcic, Jörg Lindenmann, Julia Kargl, Rudolf Schicho
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Cannabinoid (CB) receptors (CB1 and CB2) are expressed on cancer cells and their expression influences carcinogenesis in various tumor entities. Cells of the tumor microenvironment (TME) also express CB receptors, however, their role in tumor develop
Externí odkaz:
https://doaj.org/article/8fc695dd4a07458a91b2e4e48bd4b41a
Autor:
Nejra Cosic-Mujkanovic, Paulina Valadez-Cosmes, Kathrin Maitz, Anna Lueger, Zala N. Mihalic, Marah C. Runtsch, Melanie Kienzl, Michael J. Davies, Christine Y. Chuang, Akos Heinemann, Rudolf Schicho, Gunther Marsche, Julia Kargl
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1587 (2023)
Myeloperoxidase (MPO) is a neutrophil-derived enzyme that has been recently associated with tumour development. However, the mechanisms by which this enzyme exerts its functions remain unclear. In this study, we investigated whether myeloperoxidase c
Externí odkaz:
https://doaj.org/article/682bfad2e156490f964323c66d5ae8f4
Autor:
Georg Richtig, Melanie Kienzl, Sonja Rittchen, David Roula, Jürgen Eberle, Zina Sarif, Martin Pichler, Gerald Hoefler, Akos Heinemann
Publikováno v:
Biology, Vol 12, Iss 5, p 706 (2023)
Background: Cannabinoids are mainly used for recreational purposes, but also made their way into oncology, since these substances can be taken to increase appetite in tumour cachexia. Since there are some hints in the literature that cannabinoids mig
Externí odkaz:
https://doaj.org/article/42ac9a3f78e5456fae3933322e886bf9
Autor:
Markus Steiner, Richard Greil, Victoria M Leb-Reichl, Melanie Kienzl, Anna Kaufmann, Angelika Stoecklinger, Birgit Tockner, Sophie Kitzmueller, Nadja Zaborsky, Gabriele Brachtl, Lisa Trattner, Patrick Kreideweiss, Christian Reinsch, Steffen Panzner, Dirk Strunk, Johann W Bauer, Iris K Gratz, Christina Guttmann-Gruber, Josefina Piñón Hofbauer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/d8232231079d46b0a8ddef66d5eb1f23
Autor:
Paulina Valadez-Cosmes, Kathrin Maitz, Oliver Kindler, Sofia Raftopoulou, Melanie Kienzl, Ana Santiso, Zala Nikita Mihalic, Luka Brcic, Jörg Lindenmann, Melanie Fediuk, Martin Pichler, Rudolf Schicho, A. McGarry Houghton, Akos Heinemann, Julia Kargl
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils have been described as a phenotypically heterogeneous cell type that possess both pro- and anti-tumor properties. Recently, a subset of neutrophils isolated from the peripheral blood mononuclear cell (PBMC) fraction has been described in
Externí odkaz:
https://doaj.org/article/34db15e98bdf4ffb9ebb9e98f6bef13e
Autor:
Melanie Kienzl, Carina Hasenoehrl, Kathrin Maitz, Arailym Sarsembayeva, Ulrike Taschler, Paulina Valadez-Cosmes, Oliver Kindler, Dusica Ristic, Sofia Raftopoulou, Ana Santiso, Thomas Bärnthaler, Luka Brcic, Lisa Hahnefeld, Robert Gurke, Dominique Thomas, Gerd Geisslinger, Julia Kargl, Rudolf Schicho
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Monoacylglycerol lipase (MGL) expressed in cancer cells influences cancer pathogenesis but the role of MGL in the tumor microenvironment (TME) is less known. Using a syngeneic tumor model with KP cells (KrasLSL-G12D/p53fl/fl; from mouse lung adenocar
Externí odkaz:
https://doaj.org/article/232b65eeccc3450991a17b0f0c509451
Autor:
Melanie Kienzl, Carina Hasenoehrl, Paulina Valadez-Cosmes, Kathrin Maitz, Arailym Sarsembayeva, Eva Sturm, Akos Heinemann, Julia Kargl, Rudolf Schicho
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
In many types of cancer, presence of eosinophils in tumors correlate with an improved disease outcome. In line with this, activated eosinophils have been shown to reduce tumor growth in colorectal cancer (CRC). Interleukin (IL)-33 has recently emerge
Externí odkaz:
https://doaj.org/article/2388d2cea628414ca45b7c278ddf7908