Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melanie Katz"'
Publikováno v:
Dentistry Journal, Vol 12, Iss 10, p 315 (2024)
Introduction: Regenerative medicine is revolutionizing oral and maxillofacial surgeries with stem cells, particularly mesenchymal stem cells, for tissue and bone regeneration. Despite promising in-vitro results, human trials are limited. A systematic
Externí odkaz:
https://doaj.org/article/55dd4c55a8764fe98ca21e93d1e2ae6b
Autor:
Lulu Huang, Sagar S Damle, Sheri Booten, Priyam Singh, Mahyar Sabripour, Jeff Hsu, Minji Jo, Melanie Katz, Andy Watt, Christopher E Hart, Susan M Freier, Brett P Monia, Shuling Guo
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define long noncoding RNAs (lncRNAs) that participa
Externí odkaz:
https://doaj.org/article/6cb40089f7c54364ba90740f1b4158a0
Autor:
Sarah Greenlee, Brett P. Monia, Chenguang Zhao, Melanie Katz, Jeff Crosby, Hiroshi Kawabe, Mccaleb Michael L, Daniela Rotin, Chong Jiang, Dong Bai, Shuling Guo
Publikováno v:
Journal of Cystic Fibrosis. 16:671-680
Background Epithelial sodium channel (ENaC, Scnn1 ) hyperactivity in the lung leads to airway surface dehydration and mucus accumulation in cystic fibrosis (CF) patients and in mice with CF-like lung disease. Methods We identified several potent ENaC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405b8c68fcbb7a8aa278a4b11d88bc7d
https://doi.org/10.1016/j.jcf.2017.05.003
https://doi.org/10.1016/j.jcf.2017.05.003
Autor:
Prashant Rajbhandari, Loren G. Fong, Aldons J. Lusis, Jiexin Wang, Stephen G. Young, Jaspreet S. Sandhu, Laurent Vergnes, Bo Wang, Tamer Sallam, Stephen T. Smale, Cynthia Hong, Melanie Katz, Peter Tontonoz, Brandon J. Thomas, Marcus M. Seldin, An-Chieh Feng, Richard T. Lee, Karen Reue
Publikováno v:
Cell. 172(1-2)
Signaling pathways that promote adipose tissue thermogenesis are well characterized, but the limiters of energy expenditure are largely unknown. Here, we show that ablation of the anti-inflammatory cytokine IL-10 improves insulin sensitivity, protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216575680c16a1123b00efc50ab63e28
https://pubmed.ncbi.nlm.nih.gov/29249357
https://pubmed.ncbi.nlm.nih.gov/29249357
Autor:
Jaspreet S. Sandhu, Julian P. Whitelegge, Xiaohui Wu, Peter Tontonoz, Marius Jones, Ascia Eskin, Cynthia Hong, Richard T. Lee, David Casero, Thomas Q. de Aguiar Vallim, Li Zhang, Tamer Sallam, Thomas Gilliland, Melanie Katz
Publikováno v:
Nature, vol 534, iss 7605
Liver X receptors (LXRs) are transcriptional regulators of cellular and systemic cholesterol homeostasis. Under conditions of excess cholesterol, LXR activation induces the expression of several genes involved in cholesterol efflux, facilitates chole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5795c16bce205b062fe51dec55444e18
https://escholarship.org/uc/item/3dz8j48x
https://escholarship.org/uc/item/3dz8j48x
Autor:
Melissa McAlonis-Downes, Don W. Cleveland, Leonard Petrucelli, Sandrine Da Cruz, Charles J. Heyser, Michael Baughn, Jeffery Engelhardt, Qiang Zhu, Seung J. Chun, Melanie Katz, Philip Van Damme, Christopher Shaw, Pieter J. de Jong, Brian Myers, Louis De Muynck, Stephen M. Hedrick, Chris J. Jung, Derek Schulte, Shuying Sun, C. Frank Bennett, Oleksandr Platoshyn, Arnaud Delpoux, Deborah A. Swing, Andrew T. Watt, Clotilde Lagier-Tourenne, Amanda Seelman, John Ravits, Daniel T. Utzschneider, Frank Rigo, Lino Tessarollo, Lillian M. Daughrity, Paymaan Jafar-Nejad, Jie Jiang, Tania F. Gendron, Martin Marsala, Shuo-Chien Ling, M. Colin Ard, Kevin Drenner, Dieter Edbauer, Jennifer E. Stauffer, Shahram Saberi
Publikováno v:
Neuron, vol 90, iss 3
Neuron 90(3), 535-550 (2016). doi:10.1016/j.neuron.2016.04.006
Neuron 90(3), 535-550 (2016). doi:10.1016/j.neuron.2016.04.006
Hexanucleotide expansions in C9ORF72 are the most frequent genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. Disease mechanisms were evaluated in mice expressing C9ORF72 RNAs with up to 450 GGGGCC repeats or with one or both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046e29f4457663e48cf49f14a5b34c34
https://escholarship.org/uc/item/9q41g6q8
https://escholarship.org/uc/item/9q41g6q8
Autor:
Thazha P. Prakash, Husam S. Younis, Susan M. Freier, Melanie Katz, Stanley T. Crooke, C. Frank Bennett, Todd Machemer, Sebastien A. Burel, Huynh-Hoa Bui, Christopher E. Hart, Eric E. Swayze, Andrew T. Watt, Patrick Cauntay, Punit P. Seth, Mahyar Sabripour, Jill Hsiao, Scott P. Henry, Amy Dan, Gene Hung
Publikováno v:
Nucleic Acids Research
High affinity antisense oligonucleotides (ASOs) containing bicylic modifications (BNA) such as locked nucleic acid (LNA) designed to induce target RNA cleavage have been shown to have enhanced potency along with a higher propensity to cause hepatotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84634983f76ef18c0683f4653d66581
https://pubmed.ncbi.nlm.nih.gov/26553810
https://pubmed.ncbi.nlm.nih.gov/26553810
Autor:
Brett P. Monia, Sagar S. Damle, Minji Jo, Andrew T. Watt, Priyam Singh, Jeff Hsu, Shuling Guo, Sheri L. Booten, Melanie Katz, Susan M. Freier, Christopher E. Hart, Lulu Huang, Mahyar Sabripour
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
PLoS ONE, Vol 10, Iss 7, p e0132798 (2015)
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define long noncoding RNAs (lncRNAs) that participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b272f6098e543afd10f0a0131b3487
http://europepmc.org/articles/PMC4514479
http://europepmc.org/articles/PMC4514479
Autor:
Patrick Liu, Qiang Zhu, Gene W. Yeo, Sebastian Markmiller, John Ravits, C. Frank Bennett, Andrew T. Watt, Jinsong Qiu, Robert H. Baloh, Kevin Drenner, Hairi Li, Melanie Katz, Magdalini Polymenidou, Jonathan W. Artates, Scott R. VandenBerg, Jie Jiang, Donald P. Pizzo, Clotilde Lagier-Tourenne, Shuying Sun, Frank Rigo, Don W. Cleveland, Michael Baughn, Matthew B. Harms, Melissa McAlonis-Downes, Janet Cady, Seung J. Chun, Kasey R. Hutt, Shuo-Chien Ling, Xiang-Dong Fu, Ying Sun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 110, iss 47
Expanded hexanucleotide repeats in the chromosome 9 open reading frame 72 (C9orf72) gene are the most common genetic cause of ALS and frontotemporal degeneration (FTD). Here, we identify nuclear RNA foci containing the hexanucleotide expansion (GGGGC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaeefae3930b3eb669e69b88345201c
https://escholarship.org/uc/item/0943j953
https://escholarship.org/uc/item/0943j953