Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melanie K. Stewart"'
Autor:
Melanie K. Stewart, Luca Hoehne, Stefanie Dudczig, Deidre M. Mattiske, Andrew J. Pask, Patricia R. Jusuf
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 251, Iss , Pp 114541- (2023)
Endocrine disrupting chemicals (EDCs) can interact with native hormone receptors to interfere with and disrupt hormone signalling that is necessary for a broad range of developmental pathways. EDCs are pervasive in our environment, in particular in o
Externí odkaz:
https://doaj.org/article/b3818036827e48e3a9f7a37f3565a129
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background The increasing incidence of reproductive disorders in humans has been attributed to in utero exposure to estrogenic endocrine disruptors. In particular, exposure of the developing testis to exogenous estrogen can negatively impact
Externí odkaz:
https://doaj.org/article/f655f475eee8478cb2b4f199eefeeffc
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10046, p 10046 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 10046, p 10046 (2021)
Sex determination triggers the differentiation of the bi-potential gonad into either an ovary or testis. In non-mammalian vertebrates, the presence or absence of oestrogen dictates gonad differentiation, while in mammals, this mechanism has been supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7787f085a04b601dbb4e6a92a18b3c8
Publikováno v:
Experimental cell research. 398(2)
Nuclear SOX9 is essential for Sertoli cell differentiation and the development of a testis. Exposure of Sertoli cells to exogenous oestrogen causes cytoplasmic retention of SOX9, inhibiting testis development and promoting ovarian development. The cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd21755754b03fac5d2284ca3d40e69
https://pubmed.ncbi.nlm.nih.gov/33271127
https://pubmed.ncbi.nlm.nih.gov/33271127
Publikováno v:
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Background The increasing incidence of reproductive disorders in humans has been attributed to in utero exposure to estrogenic endocrine disruptors. In particular, exposure of the developing testis to exogenous estrogen can negatively impact male rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac8137c2e9d9825da7636313726c010
https://pubmed.ncbi.nlm.nih.gov/32933467
https://pubmed.ncbi.nlm.nih.gov/32933467
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8377, p 8377 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The increasing incidence of testicular dysgenesis syndrome-related conditions and overall decline in human fertility has been linked to the prevalence of oestrogenic endocrine disrupting chemicals (EDCs) in the environment. Ectopic activation of oest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29068bb2fa7635b26f4155c6d0a72c17
https://doi.org/10.3390/ijms21218377
https://doi.org/10.3390/ijms21218377
Publikováno v:
Biology of reproduction. 99(6)
Exposure to estrogenic endocrine disrupting chemicals (EDCs) during in utero development has been linked to the increasing incidence of disorders of sexual development. Hypospadias, the ectopic placement of the urethra on the ventral aspect of the pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c407ab3ab8d5aab8574323b81d5027d4
https://pubmed.ncbi.nlm.nih.gov/29931162
https://pubmed.ncbi.nlm.nih.gov/29931162