Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Melanie K. Gatt"'
Autor:
Hélène Rangone, Eva Wegel, Melanie K Gatt, Eirene Yeung, Alexander Flowers, Janusz Debski, Michal Dadlez, Veerle Janssens, Adelaide T C Carpenter, David M Glover
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002225 (2011)
Protein phosphatase 2A (PP2A) plays a major role in dephosphorylating the targets of the major mitotic kinase Cdk1 at mitotic exit, yet how it is regulated in mitotic progression is poorly understood. Here we show that mutations in either the catalyt
Externí odkaz:
https://doaj.org/article/d7bdace93a5d44c98589623310365fc2
Autor:
Sarah P. Blagden, David M. Glover, Melanie K. Gatt, Karolina Lada, Yoshihiro H. Inoue, Kathryn S. Lilley, Vincent Archambault, Keiko Ichihara
Publikováno v:
Developmental Biology. 334:186-197
As the influence of mRNA translation upon cell cycle regulation becomes clearer, we searched for genes that might specify such control in Drosophila. A maternal-effect lethal screen identified mutants in the Drosophila gene for Larp (La-related prote
Autor:
Concepcion Ferraz, Phillipe Valenti, Hugo J. Bellen, Nicole Beinert, Valerie Lelaure, Beatriz de Pablos, Dana Borkova, Cathy Salles, Nadine S. Henderson, Christine Brun, Francis Galibert, David Harris, Edouard Cadieu, Wilfried Janning, Péter Deák, Paul J. McMillan, Panayiotis V. Benos, Robert D. C. Saunders, Foteini Mourkioti, Slava Bolshakov, Encarnación Madueño, Annette Peter, Alain Bucheton, George Papagiannakis, Sophie Vidal, Stéphanie Gloux, Lee Murphy, Belén Miñana, Gordon Dowe, Alain Billaud, Ulrich Schäfer, Debbie Callister, Lefteris Spanos, Yuchun He, David M. Glover, Evelyn Tait, Melanie K. Gatt, Lior Pachter, Herbert Jäckle, Lorna Campbell, Lore Dentzer, Meike Werner, Jacques Demaille, Inga Siden-Kiamos, Juan Modolell, Michael Ashburner, Robert Klapper, Fotis C. Kafatos, Christos Louis, Stéphanie Mottier, Peter Burkert, Petra Schöttler, Stéphane Dréano, Bart Barrell
Publikováno v:
EMBO reports. 3:34-38
The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics Systems, have sequenced the genome, complementing t
Autor:
Melanie K. Gatt
Publikováno v:
Oncology Times. 32:24-26
Autor:
Melanie K. Gatt, David M. Glover
Cytokinesis requires the coordination of cytoskeletal and plasma membrane dynamics. A role for phosphatidylinositol lipids has been proposed for the successful completion of cytokinesis but this is still poorly characterised. Here, we show mutants of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92497225e9ad922f9d00019612753603
https://resolver.caltech.edu/CaltechAUTHORS:20201002-140639688
https://resolver.caltech.edu/CaltechAUTHORS:20201002-140639688
Autor:
Laurent Lehmann, Melanie K. Gatt, Francois Balloux, Giuliano Callaini, Maria Giovanna Riparbelli, Mónica Bettencourt-Dias, Lee Carpenter, Ana Rodrigues-Martins, N. Carmo, David M. Glover
Publikováno v:
Current Biology, vol. 15, no. 24, pp. 2199-2207
Summary Background SAK/PLK4 is a distinct member of the polo-like kinase family. SAK −/− mice die during embryogenesis, whereas SAK +/− mice develop liver and lung tumors and SAK +/− MEFs show mitotic abnormalities. However, the mechanism und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad7e90b51e4ac8ce727f7ab7cbd2efb
https://serval.unil.ch/resource/serval:BIB_9CF1AAD386B9.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_9CF1AAD386B9.P001/REF.pdf
Autor:
David M. Glover, Melanie K. Gatt, Maria Giovanna Riparbelli, Chiara Massarelli, Matthew S. Savoian, Giuliano Callaini
Klp67A is a member of the Kip3 subfamily of microtubule destabilising kinesins, the loss of which results in abnormally long and stable pre-anaphase microtubules. Here we examine its role during cytokinesis in Drosophila primary spermatocytes that re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadf9912274225c040d17ca1022f1241
http://hdl.handle.net/11365/19035
http://hdl.handle.net/11365/19035
Autor:
Melanie K. Gatt, Giuliano Callaini, David M. Glover, Matthew S. Savoian, Maria Giovanna Riparbelli
Drosophila Klp67A belongs to the Kip3 subfamily of Kinesin-type microtubule catastrophe factors. In primary spermatocytes, loss of klp67A leads to defects in karyokinesis and cytokinesis. We show that these cells formed disorganised, bipolar spindles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1d02e268520047546a8af10d7343d5
http://hdl.handle.net/11365/17810
http://hdl.handle.net/11365/17810
Publikováno v:
Journal of cell science. 116(Pt 5)
The weak spindle integrity checkpoint in Drosophila spermatocytes has revealed a novel function of the gamma-tubulin ring complex (gammaTuRC) in maintaining spindle bipolarity throughout meiosis. Bipolar and bi-astral spindles could form in Drosophil
Autor:
Juan Modolell, Michael Ashburner, Robert D. C. Saunders, David A. Harris, Paul J. McMillan, Lorna Campbell, Belén Miñana, Christos Louis, Herbert Jäckle, Dana Borkova, Lior Pachter, Evelyn Tait, Stéphanie Gloux, Melanie K. Gatt, Debbie Callister, Inga Siden-Kiamos, Meike Werner, Gordon Dowe, George Papagiannakis, Fotini Mourkioti, Encarnación Madueño, David M. Glover, Nicole Beinert, Cathy Salles, Alain Bucheton, Christine Brun, Edouard Cadieu, Lee Murphy, Valerie Lelaure, Stéphane Dréano, Sophie Vidal, Beatriz de Pablos, Lefteris Spanos, Concepcion Ferraz, Phillipe Valenti, Francis Galibert, Jacques Demaille, Annette Peter, Slava Bolshakov, Fotis C. Kafatos, Alain Billaud, Ulrich Schäfer, Petra Schöttler, Stéphanie Mottier, Nadine S. Henderson, Bart Barrell, Panayiotis V. Benos
Publikováno v:
Genome research. 11(5)
We present the sequence of a contiguous 2.63 Mb of DNA extending from the tip of the X chromosome ofDrosophila melanogaster. Within this sequence, we predict 277 protein coding genes, of which 94 had been sequenced already in the course of studying t