Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Melanie J. Chaplin"'
Autor:
Timm Konold, Laura J. Phelan, Ben R. Donnachie, Melanie J. Chaplin, Saira Cawthraw, Lorenzo González
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-13 (2017)
Abstract Background A study to investigate transmission of classical scrapie via goat milk was carried out in sheep: firstly, lambs were challenged orally with goat scrapie brain homogenate to confirm transmission of scrapie from goats to sheep. In t
Externí odkaz:
https://doaj.org/article/8497f195e06f41fb9718e4b5ef3bf3bd
Autor:
Marion M. Simmons, S. Jo Moore, Timm Konold, Lisa Thurston, Linda A. Terry, Leigh Thorne, Richard Lockey, Chris Vickery, Stephen A.C. Hawkins, Melanie J. Chaplin, John Spiropoulos
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 5, Pp 848-854 (2011)
To investigate the possibility of oral transmission of atypical scrapie in sheep and determine the distribution of infectivity in the animals’ peripheral tissues, we challenged neonatal lambs orally with atypical scrapie; they were then killed at 1
Externí odkaz:
https://doaj.org/article/b0c5b9d15f034a31b3abff504584c57e
Autor:
Marion M Simmons, S Jo Moore, Richard Lockey, Melanie J Chaplin, Timm Konold, Christopher Vickery, John Spiropoulos
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117063 (2015)
The interactions of host and infecting strain in ovine transmissible spongiform encephalopathies are known to be complex, and have a profound effect on the resulting phenotype of disease. In contrast to classical scrapie, the pathology in naturally-o
Externí odkaz:
https://doaj.org/article/f66f031f7e654a07ba5de83684ad339f
Autor:
Laura J. Phelan, Ben R. Donnachie, Lorenzo González, Melanie J. Chaplin, Timm Konold, Saira Cawthraw
Publikováno v:
BMC Veterinary Research, Vol 13, Iss 1, Pp 1-13 (2017)
BMC Veterinary Research
BMC Veterinary Research
Background A study to investigate transmission of classical scrapie via goat milk was carried out in sheep: firstly, lambs were challenged orally with goat scrapie brain homogenate to confirm transmission of scrapie from goats to sheep. In the second
Autor:
L. Davis, Melanie J. Chaplin, M. Denyer, Richard Lockey, Ben C. Maddison, John Spiropoulos, M.J. Stack, Kevin C. Gough, Marion Simmons, Matthew J. O’Connor, Christopher M. Vickery, Leigh Thorne, Keith Bishop, S. Simon
Publikováno v:
Journal of Clinical Microbiology. 53:2593-2604
Current European Commission (EC) surveillance regulations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive small ruminant (SR) samples in order to classify them as bovine spongiform encephalopathy (BSE) or
Autor:
S. A. C. Hawkins, L.A. Davis, E. M. Jones, R. Focosi-Snyman, P. Bellerby, J. A. Cooper, L. Thurston, M.J. Stack, Gerald A. H. Wells, L. Powell, Marion Simmons, Y. I. Spencer, Paul R. Webb, Mark Arnold, Alberto Vidal-Diez, S. J. Moore, John Spiropoulos, Melanie J. Chaplin, Sharon Everitt
Publikováno v:
Journal of Comparative Pathology. 145:289-301
European regulations for the control of bovine spongiform encephalopathy (BSE) decree destruction of the intestines from slaughtered cattle, therefore producers have been obliged to import beef casings from countries with a negligible BSE risk. This
Autor:
Christopher M. Vickery, Timm Konold, Stephen A. C. Hawkins, Linda A. Terry, Lisa C. Thurston, S. Jo Moore, Marion Simmons, John Spiropoulos, Melanie J. Chaplin, Leigh Thorne, Richard Lockey
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 5, Pp 848-854 (2011)
Emerging Infectious Diseases
Emerging Infectious Diseases
Such transmission results in peripheral tissue infectivity that is not detectable by current surveillance screening methods.
To investigate the possibility of oral transmission of atypical scrapie in sheep and determine the distribution of infec
To investigate the possibility of oral transmission of atypical scrapie in sheep and determine the distribution of infec
Autor:
Michael J Stack, Rosemary E. Sallis, Richard Lockey, Sarah Simonini, John Spiropoulos, Melanie J. Chaplin, Katy E. Beck
Publikováno v:
Brain Pathology (Zurich, Switzerland)
Primary isolation of bovine spongiform encephalopathy (BSE) in RIII mice generates a lesion profile believed to be reproducible and distinct from that produced by classical scrapie. This profile, which is characterized by peaks at gray matter areas 1
Autor:
L.A. Davis, R. Jenkins, Linda A. Terry, M.J. Stack, Ginny C. Saunders, Melanie J. Chaplin, Leigh Thorne, R. Focosi-Snyman, Sharon Everitt, Saira Cawthraw
Publikováno v:
Zoonoses and Public Health. 56:376-383
Bovine spongiform encephalopathy (BSE) was first identified in Great Britain (GB) in 1986 and was subsequently detected in many other countries, worldwide. A decade after the start of the bovine epidemic, the first cases of new variant Creutzfeldt-Ja
Publikováno v:
Acta Neuropathologica. 116:547-559
Scrapie belongs to a group of diseases known as the transmissible spongiform encephalopathies or prion diseases. Two different categories of naturally occurring scrapie have been identified: classical scrapie, which was first recorded around 1750, an