Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Melanie J, Millier"'
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Objectives TNF-α inhibitors are widely used in rheumatoid arthritis (RA) with varying success. Response to TNF-α inhibition may reflect the evolution of rheumatoid inflammation through fluctuating stages of TNF-α dependence. Our aim was t
Externí odkaz:
https://doaj.org/article/d1fe401cde29445a8653cea51c06ebc1
Autor:
Kelly J McKelvey, Melanie J Millier, Terence C Doyle, Lisa K Stamp, John Highton, Paul A Hessian
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202135 (2018)
OBJECTIVE:To determine whether the expression of IL17A and CD21L genes in inflamed rheumatoid synovia is associated with the neogenesis of ectopic lymphoid follicle-like structures (ELS), and if this aids the stratification of rheumatoid inflammation
Externí odkaz:
https://doaj.org/article/8f7122239da544cd93f1643cae16ae99
Publikováno v:
Genes & Immunity. 21:249-259
We aimed to assess expression of genes encoding the heterodimeric IL-27 cytokine and constituent subunits of the Il-27 receptor in rheumatoid arthritis (RA), including in extra-articular, subcutaneous rheumatoid nodules. Comparing between nodules and
Publikováno v:
Arthritis researchtherapy. 24(1)
TNF-α inhibitors are widely used in rheumatoid arthritis (RA) with varying success. Response to TNF-α inhibition may reflect the evolution of rheumatoid inflammation through fluctuating stages of TNF-α dependence. Our aim was to assess plasma conc
Publikováno v:
Genes and immunity. 21(4)
We aimed to assess expression of genes encoding the heterodimeric IL-27 cytokine and constituent subunits of the Il-27 receptor in rheumatoid arthritis (RA), including in extra-articular, subcutaneous rheumatoid nodules. Comparing between nodules and
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Subtle molecular differences indicate the heterogeneity present in a number of disease settings. Digital-PCR (dPCR) platforms achieve the necessary levels of sensitivity and accuracy over standard quantitative RT-PCR (qPCR) that promote their use for
Publikováno v:
The Anatomical Record. 296:1943-1953
Primary cilia are small, sensory organelles projecting from virtually all cells and are vital for cellular and tissue function. Their distribution in bovine mammary tissue has not previously been assessed, despite the potential for these organelles t
Autor:
Emma L, Houlder, Melanie J, Millier, John, Highton, David, Gwynne-Jones, Lisa K, Stamp, Paul A, Hessian
Publikováno v:
Clinical and experimental rheumatology. 35(6)
We sought further understanding of the association between methotrexate (MTX) therapy and accelerated development of subcutaneous rheumatoid nodules. The objective was to establish expression of genes involved in the transport, metabolism, and mechan
Autor:
Melanie J Millier, John Highton, Paul A. Hessian, Terence Doyle, Lisa K. Stamp, Kelly J. McKelvey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0202135 (2018)
PLoS ONE, Vol 13, Iss 8, p e0202135 (2018)
Objective To determine whether the expression of IL17A and CD21L genes in inflamed rheumatoid synovia is associated with the neogenesis of ectopic lymphoid follicle-like structures (ELS), and if this aids the stratification of rheumatoid inflammation
Publikováno v:
REPRODUCTION. 137:721-726
Opioid binding protein/cell adhesion molecule-like gene (OPCML) is frequently inactivated in epithelial ovarian cancer, but the role of this membrane protein in normal reproductive function is unclear. The ovarian surface epithelium (OSE) is thought