Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Melanie Horton"'
Autor:
Jennifer D. Galli, Melanie Horton, Eberhard Durr, Gwendolyn J. Heidecker, Daniel Freed, Arthur Fridman, Dai Wang, Lan Zhang
Publikováno v:
Vaccines, Vol 10, Iss 2, p 184 (2022)
Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i
Externí odkaz:
https://doaj.org/article/285739d0545a4c29948d2f7d7e701610
Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes.
Autor:
Leike Li, Weixu Meng, Melanie Horton, Daniel R DiStefano, Elizabeth A Thoryk, Jennifer M Pfaff, Qihui Wang, Georgina T Salazar, Trevor Barnes, Benjamin J Doranz, Andrew J Bett, Danilo R Casimiro, Kalpit A Vora, Zhiqiang An, Ningyan Zhang
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007716 (2019)
There is still no safe and effective vaccine against dengue virus infection. Epidemics of dengue virus infection are increasingly a threat to human health around the world. Antibodies generated in response to dengue infection have been shown to impac
Externí odkaz:
https://doaj.org/article/987313e68b584a3482591ce5d30cb479
Autor:
Susan Secore, Su Wang, Julie Doughtry, Jinfu Xie, Matt Miezeiewski, Richard R Rustandi, Melanie Horton, Rachel Xoconostle, Bei Wang, Catherine Lancaster, Adam Kristopeit, Sheng-Ching Wang, Sianny Christanti, Salvatore Vitelli, Marie-Pierre Gentile, Aaron Goerke, Julie Skinner, Erica Strable, David S Thiriot, Jean-Luc Bodmer, Jon H Heinrichs
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170640 (2017)
Clostridium difficile infections (CDI) are a leading cause of nosocomial diarrhea in the developed world. The main virulence factors of the bacterium are the large clostridial toxins (LCTs), TcdA and TcdB, which are largely responsible for the sympto
Externí odkaz:
https://doaj.org/article/586f53328522451cb04437ff28ab9d90
Autor:
Amy S. Espeseth, Maoli Yuan, Michael Citron, Lucia Reiserova, Gavin Morrow, Aaron Wilson, Melanie Horton, Mark Rukhman, Keith Kinek, Fuxiang Hou, Shui L. Li, Fengsheng Li, Yesle Choi, Gwen Heidecker, Bin Luo, Guoxin Wu, Lan Zhang, Erica Strable, Joanne DeStefano, Susan Secore, Tarit K. Mukhopadhyay, Douglas D. Richardson, Eddy Sayeed, Lisa S. Welch, Andrew J. Bett, Mark B. Feinberg, Swati B. Gupta, Christopher L. Cooper, Christopher L. Parks
Publikováno v:
EBioMedicine. 82
To investigate a vaccine technology with potential to protect against coronavirus disease 2019 (COVID-19) and reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with a single vaccine dose, we developed a SARS-CoV-2 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4b5258d6af9a35d05eb37e1ddb9c48
https://pubmed.ncbi.nlm.nih.gov/35915046
https://pubmed.ncbi.nlm.nih.gov/35915046
Autor:
Jennifer D. Galli, Melanie Horton, Eberhard Durr, Gwendolyn J. Heidecker, Daniel Freed, Arthur Fridman, Dai Wang, Lan Zhang
Publikováno v:
Vaccines; Volume 10; Issue 2; Pages: 184
Glycoprotein E (gE) and glycoprotein I (gI) are expressed as a heterodimer on the surface of Herpes simplex virus (HSV). Glycoprotein E binds Fc domain of immunoglobulin G (IgG) and inhibits activities mediated by the IgG Fc domain, contributing to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a40374e45d5b90c483d418bebaf91e7
https://pubmed.ncbi.nlm.nih.gov/35214644
https://pubmed.ncbi.nlm.nih.gov/35214644
Autor:
Deepti Chugh, Stephanie Cawker, Kristian Aquilina, Aneeta Gandekar, Melanie Horton, Agnieszka Roborszka, Eleanor Main
Publikováno v:
Digital posters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427c04233a48d62aa2b90f1e8e274472
https://doi.org/10.1136/archdischild-2021-gosh.100
https://doi.org/10.1136/archdischild-2021-gosh.100
Autor:
Melanie Horton, Kara S. Cox, Brian Squadroni, Dai Wang, Michael Minnier, Zhifeng Chen, Aimin Tang, Jessica Peters, Jennifer D. Galli, Arthur Fridman, Kalpit A. Vora, Scott Cosmi, Nicole L Sullivan
Publikováno v:
Journal of virological methods. 297
Background Plaque Reduction Neutralization Test (PRNT) is the standard assay used for measuring neutralizing antibody responses to Herpes simplex virus type-2 (HSV-2). The PRNT is a cumbersome, time-consuming and laborious assay. The development of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24a2e01f619afc75ccf12240e208907
https://pubmed.ncbi.nlm.nih.gov/34437874
https://pubmed.ncbi.nlm.nih.gov/34437874
Autor:
Georgina To'a Salazar, Elizabeth Thoryk, Danilo R. Casimiro, Qihui Wang, Benjamin J. Doranz, Weixu Meng, Daniel R. DiStefano, Kalpit A. Vora, Andrew J. Bett, Trevor Barnes, Jennifer M. Pfaff, Ningyan Zhang, Leike Li, Zhiqiang An, Melanie Horton
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007716 (2019)
PLoS Pathogens
PLoS Pathogens
There is still no safe and effective vaccine against dengue virus infection. Epidemics of dengue virus infection are increasingly a threat to human health around the world. Antibodies generated in response to dengue infection have been shown to impac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb900071e4b986e0433c492a4dcd2c9
https://doaj.org/article/987313e68b584a3482591ce5d30cb479
https://doaj.org/article/987313e68b584a3482591ce5d30cb479
Autor:
Benjamin J. Doranz, Hao Yan, Melanie Horton, Aimin Tang, Sheri Dubey, Danilo R. Casimiro, Zhifeng Chen, Daniel J. DiStefano, Kalpit A. Vora, Xin-Min Wang, Rachel H. Fong, Kara S. Cox, Andrew Ettenger
Publikováno v:
mAbs
Monitoring antigen-specific memory B cells and the antibodies they encode is important for understanding the specificity, breadth and duration of immune response to an infection or vaccination. The antibodies isolated could further help design vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768646b2b83f97308ac4310de46c89e1
https://doi.org/10.1080/19420862.2015.1109757
https://doi.org/10.1080/19420862.2015.1109757
Publikováno v:
Journal of Clinical Microbiology. 51:2970-2976
Pathogenic bacteria produce several virulence factors that help them establish infection in permissive hosts. Bacterial toxins are a major class of virulence factors and hence are attractive therapeutic targets for vaccine development. Here, we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f75fb2e233c90fb5736108ae96abc0
https://doi.org/10.1128/jcm.01161-13
https://doi.org/10.1128/jcm.01161-13