Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Melanie Hofmann"'
Autor:
Mario Kuttke, Dominika Hromadová, Ceren Yildirim, Julia S. Brunner, Andrea Vogel, Hannah Paar, Sophie Peters, Maria Weber, Melanie Hofmann, Martina Kerndl, Markus Kieler, Hannes Datler, Laszlo Musiejovsky, Manuel Salzmann, Michaela Lang, Klara Soukup, Angela Halfmann, Omar Sharif, Gernot Schabbauer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and main signaling pathways activating innate immune cells and how they modulate adaptive immuni
Externí odkaz:
https://doaj.org/article/8fc40d72faab43029d584838fb78452a
Autor:
Julia S. Brunner, Loan Vulliard, Melanie Hofmann, Markus Kieler, Alexander Lercher, Andrea Vogel, Marion Russier, Johanna B. Brüggenthies, Martina Kerndl, Victoria Saferding, Birgit Niederreiter, Alexandra Junza, Annika Frauenstein, Carina Scholtysek, Yohei Mikami, Kristaps Klavins, Gerhard Krönke, Andreas Bergthaler, John J. O’Shea, Thomas Weichhart, Felix Meissner, Josef S. Smolen, Paul Cheng, Oscar Yanes, Jörg Menche, Peter J. Murray, Omar Sharif, Stephan Blüml, Gernot Schabbauer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Multinucleated giant cells (MGCs) are important in the pathogenesis of various diseases. Here, the authors demonstrate that extracellular presence of the amino acid arginine is required for MGC formation and metabolism, suggesting a translational imp
Externí odkaz:
https://doaj.org/article/28055bd4c7454a9b869483a12530bfc2
Autor:
Martina Kerndl, Alexander Hajto, Gernot Schabbauer, Paulina M. Dominiak, Mark A. Febbraio, Melanie Hofmann, Emma Estevez, Amanda E. Brandon, Andrea Vogel, Marta Kulik, Kristaps Klavins, Jörg Menche, Florian Gruber, Mario Kuttke, Lucia Quemada Garrido, Andreas Bergthaler, Ana Korosec, Casey L. Egan, Martina Schweiger, Alexander Lercher, Ildiko Mesteri, Thomas Weichhart, Marlene Pühringer, Omar Sharif, Maria W. Górna, Markus Kieler, Michael Caldera, Julia S. Brunner
Publikováno v:
Nature Metabolism. 2:1427-1442
Adipose tissue macrophages (ATMs) display tremendous heterogeneity depending on signals in their local microenvironment and contribute to the pathogenesis of obesity. The phosphoinositide 3-kinase (PI3K) signalling pathway, antagonized by the phospha
Publikováno v:
ChemistrySelect. 5:10010-10014
Autor:
Stephan Enthaler, Nicolo Santangelo, Elena Fedorenko, Christoph Alberti, Tim-Oliver Kindler, Melanie Hofmann, Jannik Kessler, Sarah Eckelt
Publikováno v:
ChemistrySelect. 5:4231-4234
Publikováno v:
Polymer Chemistry. 11:2625-2629
In recent times, plastics derived from renewable resources have received significant consideration as alternatives to plastics based on fossil resources. Nevertheless, some challenging issues, for instance the embedding of these plastics in a future
Publikováno v:
ChemistrySelect. 4:12638-12642
Autor:
Andrea Vogel, Katharina Martin, Klara Soukup, Angela Halfmann, Martina Kerndl, Julia S. Brunner, Melanie Hofmann, Laura Oberbichler, Ana Korosec, Mario Kuttke, Hannes Datler, Markus Kieler, Laszlo Musiejovsky, Alexander Dohnal, Omar Sharif, Gernot Schabbauer
Publikováno v:
Cell reports. 38(8)
Dendritic cells (DCs) induce peripheral T cell tolerance, but cell-intrinsic signaling cascades governing their stable tolerogenesis remain poorly defined. Janus Kinase 1 (JAK1) transduces cytokine-receptor signaling, and JAK inhibitors (Jakinibs), i
Publikováno v:
The Febs Journal
Macrophages represent the first line of defence in innate immune responses and additionally serve important functions for the regulation of host inflammation and tissue homeostasis. The M1/M2 model describes the two extremes of macrophage polarizatio