Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Melanie Heywood"'
Autor:
Achim A. Jungbluth, Lloyd J. Old, Gerd Ritter, Geoffrey Y. Ku, Yinyan Xu, Teresa S. Rasalan, Erika Ritter, Ruth Ann Roman, James P. Allison, Humilidad F. Gallardo, Melanie Heywood, Jedd D. Wolchok, Hao Li, Neil H. Segal, Evelina Pogoriler, Sacha Gnjatic, Sarah Powel, Gregor Manukian, Jianda Yuan, Stephanie L. Terzulli
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20410-20415
Blockade of inhibitory signals mediated by cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) has been shown to enhance T cell responses and induce durable clinical responses in patients with metastatic melanoma. The functional impact of anti-CTLA-
Autor:
Stephanie L. Terzulli, Susan E. Krown, Paul B. Chapman, Teresa S. Rasalan, Miguel Perales, Jianda Yuan, Alan N. Houghton, Katherine S. Panageas, Isabelle Riviere, Humilidad F. Gallardo, Yan Zhang, Rajaram Ranganathan, Philip O. Livingston, Jedd D. Wolchok, Melanie Heywood, Jian Wang
Publikováno v:
Molecular Therapy. 15:2044-2050
Immunity to self antigens on cancer is constrained by tolerance/ignorance. DNA vaccines encoding xenogeneic differentiation antigens, such as tyrosinase (TYR), mediate tumor protection and regression in implantable mouse models, and dogs with spontan
Autor:
Paul B. Chapman, Teresa S. Rasalan, P. O. Livingston, Jennifer Wang, Jianda Yuan, Susan E. Krown, Miguel-Angel Perales, Melanie Heywood, Humilidad F. Gallardo, Jedd D. Wolchok
Publikováno v:
Journal of Clinical Oncology. 25:3005-3005
3005 Background: T-cell and antibody responses to self antigens on cancer are usually constrained by immunologic tolerance and ignorance. We found that DNA vaccines encoding xenogeneic differentiation antigens, such as tyrosinase (TYR), can mediate t