Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Melanie Heilmann"'
Autor:
Fabian Kiessling, Nabeel Farhan, Matthias P. Lichy, Silvia Vosseler, Melanie Heilmann, Martin Krix, Peter Bohlen, Dan W. Miller, Margareta M. Mueller, Wolfhard Semmler, Norbert E. Fusenig, Stefan Delorme
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 3, Pp 213-223 (2004)
The purpose of our study was the investigation of early changes in tumor vascularization during antiangiogenic therapy with the vascular endothelial growth factor (VEGF) receptor 2 antibody (DC101) using dynamic contrast-enhanced magnetic resonance i
Externí odkaz:
https://doaj.org/article/8109fa4842264dd1acbff2f69ecf6fad
Autor:
Eric Gottwald, Jörg Döpfert, Melanie Heilmann, Matthias Worgull, Brigitte Altmann, Tanja Kleintschek, Stefan Giselbrecht, Roman Truckenmüller, Lothar R. Schad
Publikováno v:
Zeitschrift für medizinische physik, 23(2), 102-110. Urban und Fischer Verlag Jena
We describe the characterization of a chip-based platform (3(D)-KITChip) for the three-dimensional cultivation of cells under perfusion conditions via magnetic resonance imaging (MRI). Besides the chip, the microfluidic system is comprised of a biore
Autor:
Marc A. Brockmann, Hans U. Kerl, Martin Kramer, Hanne Boll, Christoph Groden, Melanie Heilmann, Viktor Umansky, Marcel Ramacher
Publikováno v:
Experimental Dermatology. 21:837-841
Spontaneous melanoma models in transgenic mice are increasingly used in preclinical research as they most closely match the progression of melanoma in humans. While optical inspection only allows analysis of tumors located on the skin, the accurate m
Autor:
Wilhelm Kriz, Ivo Wolf, Carsten Sticht, Daniel Schock-Kusch, John F. Bertram, Melanie Heilmann, Lina Gubhaju, Norbert Gretz, Lothar R. Schad, Sabine Neudecker
Publikováno v:
Nephrology Dialysis Transplantation. 27:100-107
Background Glomerular number and size are important risk factors for chronic kidney disease (CKD) and cardiovascular disease and have traditionally been estimated using invasive techniques. Here, we report a novel technique to count and size every gl
Publikováno v:
Magnetic Resonance in Medicine. 64:313-318
Dynamic contrast-enhanced MRI is extensively studied to define and evaluate biomarkers for early assessment of vasculature-targeting therapies. In this study, two-dimensional and three-dimensional radial multi-gradient-echo techniques for dynamic R*2
Autor:
Frank G. Zöllner, Stefan O. Schoenberg, Johanna Nissen, Melanie Heilmann, Moritz B. Mie, Lothar R. Schad, Henrik J. Michaely
Publikováno v:
Zeitschrift für Medizinische Physik. 20:143-150
Susceptibility weighted imaging provides diagnostic information in strokes, hemorrhages, and cerebral tumors and has proven to be a valuable tool in imaging venous vessels in the cerebrum. The SWI principle is based on the weighting of T(2)* weighted
Autor:
Michael Peller, Steven Sourbron, Julien Vautier, Andreas Biffar, Christine Walczak, Andreas Volk, Melanie Heilmann
Publikováno v:
Magnetic Resonance in Medicine. 62:672-681
The aim of this study was to propose and evaluate a methodology to analyze simultaneously acquired T-weighted dynamic susceptibility contrast (DSC) MRI and T1-weighted dynamic contrast enhanced (DCE) MRI data. Two generalized models of T-relaxation a
Publikováno v:
Contrast Media & Molecular Imaging. 4:66-72
An experimental setup consisting of a hollow fiber module (HFM) was developed for the in vitro study of contrast agent (CA) permeability. Controllable flow and known fiber characteristics allowed permeability studies under well-defined conditions wit
Autor:
Mihaela Lupu, Melanie Heilmann, Joël Mispelter, Christine Walczak, Julien Vautier, Andreas Volk, Carole D. Thomas, Jean-Luc Dimicoli
Publikováno v:
Magnetic Resonance Materials in Physics, Biology and Medicine. 20:193-203
A double-delay SR-MGE-SNAP sequence allowing simultaneous T1 and T2* measurement was developed for integrating arterial input function (AIF) measurement into DCE MRI. Implemented on a 4.7-T animal MR system, this technique was applied to mice with co
Publikováno v:
Investigative Radiology. 41:536-543
We sought to compare pharmacokinetic modeling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data by assuming a linear and nonlinear relationship between signal intensity (SI) and contrast agent (CA) concentration.Data sets were ge