Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Melanie Giesen"'
Autor:
Hélène Willer, Gabriele Spohn, Kimberly Morgenroth, Corinna Thielemann, Susanne Elvers-Hornung, Peter Bugert, Bruno Delorme, Melanie Giesen, Thomas Schmitz-Rixen, Erhard Seifried, Christiane Pfarrer, Richard Schäfer, Karen Bieback
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow. To mitigate donor variabilities and to obtain robust and valid clinical data, we aimed fi
Externí odkaz:
https://doaj.org/article/5373656f19b54ecbaf9a6cac11c3bbdb
Autor:
Patricia Klaka, Sabine Grüdl, Bernhard Banowski, Melanie Giesen, Andrea Sättler, Peter Proksch, Thomas Welss, Thomas Förster
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182752 (2017)
Dysregulated human eccrine sweat glands can negatively impact the quality-of-life of people suffering from disorders like hyperhidrosis. Inability of sweating can even result in serious health effects in humans affected by anhidrosis. The underlying
Externí odkaz:
https://doaj.org/article/3dc55d22b4e74e1b816a513ce0cc8356
Autor:
Wolfgang Funk, Jérémy Chéret, Thomas Welss, Ralf Paus, Melanie Giesen, J. Gherardini, Yuval Ramot, Gudrun Heinen, Marta Bertolini
Publikováno v:
International journal of cosmetic scienceReferences. 42(1)
Theophylline is a phosphodiesterase inhibitor that is being used clinically for asthma therapy. In addition, it is recognized as a cosmetic agent with possible anti-ageing and anti-oxidative properties. Nevertheless, how it affects human skin is stil
Autor:
Melanie Giesen, Peter Brenneisen, Okka Scholz, Lirija Alili, Olaf Holtkötter, Johanna Diekmann
Publikováno v:
Experimental Dermatology. 25:56-61
Human skin undergoes morphological, biochemical and functional modifications during the ageing process. This study was designed to produce a 3-dimensional (3D) skin equivalent in vitro reflecting some aspects of in vivo aged skin. Reconstructed skin
Autor:
Matthias Klinger, Ralf Paus, Wolfgang Funk, Jérémy Chéret, Rachel E.B. Watson, Melanie Giesen, A.K. Langton, Barbara Kofler, M. Alam, Jana Knuever, Silvia Vidali, Swantje Haeger
Publikováno v:
Vidali, S, Cheret, J, Giesen, M, Haeger, S, Alam, M, Watson, R, Langton, A, Klinger, M, Knuever, J, Funk, W, Kofler, B & Paus, R 2016, ' Thyroid hormones enhance mitochondrial function in human epidermis ', Journal of Investigative Dermatology, vol. 136, no. 10, pp. 2003–2012 . https://doi.org/10.1016/j.jid.2016.05.118
Since it is unknown whether thyroid hormones (THs) regulate mitochondrial function in human epidermis, we treated organ-cultured human skin, or isolated cultured human epidermal keratinocytes, with triiodothyronine (100 pmol/L) or thyroxine (100 nmol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f5bad4785edb0e5357c712cc1413b0
https://doi.org/10.1016/j.jid.2016.05.118
https://doi.org/10.1016/j.jid.2016.05.118
Publikováno v:
Cytotherapy; Vol 13
BACKGROUND AIMS. Intravenously applied mesenchymal stromal cells (MSC) are under investigation for numerous clinical indications. However, their capacity to activate shear stress-dependent adhesion to endothelial ligands is incompletely characterized
Autor:
Thomas Förster, Bernhard Banowski, Andrea Sättler, Sabine Grüdl, Thomas Welss, Melanie Giesen, Patricia Klaka, Peter Proksch
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182752 (2017)
PLoS ONE
PLoS ONE
Dysregulated human eccrine sweat glands can negatively impact the quality-of-life of people suffering from disorders like hyperhidrosis. Inability of sweating can even result in serious health effects in humans affected by anhidrosis. The underlying
Autor:
Melanie Giesen, Dirk Petersohn, Sabine Gruedl, Guido Fuhrmann, Andrea Koerner, Olaf Holtkoetter
Publikováno v:
Experimental Dermatology. 20:759-761
In many cultures, a youthful look is strictly linked to strong and healthy hair. Source of the hair fibre is the hair follicle, a highly specialized skin appendage. Biological alterations because of intrinsic or extrinsic stimuli can destabilize this
Publikováno v:
AGE. 36
Currently, the oxidative stress (or free radical) theory of aging is the most popular explanation of how aging occurs at the molecular level. Accordingly, a stress-induced senescence-like phenotype of human dermal fibroblasts can be induced in vitro
Autor:
Reb Watson, Silvia Vidali, Matthias Klinger, M. Alam, Melanie Giesen, Jana Knuever, S. Haeger, Ralf Paus, Jérémy Chéret, Barbara Kofler
Publikováno v:
Journal of Investigative Dermatology. 136:S172