Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Melanie G. Gareau"'
Autor:
Daniel R. Fregoso, Yasmin Hadian, Anthony C. Gallegos, Doniz Degovics, John Maaga, Ciara E. Keogh, Isaiah Kletenik, Melanie G. Gareau, R. Rivkah Isseroff
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 15, Iss , Pp 100279- (2021)
Patients with chronic wounds often have associated cognitive dysfunction and depression with an as yet unknown mechanism for this association. To address the possible causality of skin wounding inducing these changes, behavior and cognitive functions
Externí odkaz:
https://doaj.org/article/8827763d55c744f995f160970f46da36
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299006 (2024)
Light microscopy methods have continued to advance allowing for unprecedented analysis of various cell types in tissues including the brain. Although the functional state of some cell types such as microglia can be determined by morphometric analysis
Externí odkaz:
https://doaj.org/article/17999eacfdb2451ca852046e15a88951
Autor:
Andrew M F Johnson, Anne Costanzo, Melanie G Gareau, Aaron M Armando, Oswald Quehenberger, Julie M Jameson, Jerrold M Olefsky
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122195 (2015)
The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose ti
Externí odkaz:
https://doaj.org/article/e4dc7fe4437e4507b5730e5394debc14
Autor:
Frida, Fart, Samira, Salihović, Aidan, McGlinchey, Melanie G, Gareau, Matej, Orešič, Jonas, Halfvarson, Tuulia, Hyötyläinen, Ida, Schoultz
Publikováno v:
Scandinavian journal of gastroenterology. 56(11)
Environmental factors are strongly implicated in late-onset of inflammatory bowel disease. Here, we investigate whether high levels of perfluoroalkyl substances are associated with (1) late-onset inflammatory bowel disease, and (2) disturbances of th
Autor:
Ramzi Fattouh, Cong-Hui Guo, Grace Y Lam, Melanie G Gareau, Bo-Yee Ngan, Michael Glogauer, Aleixo M Muise, John H Brumell
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61629 (2013)
Recent genetic-based studies have implicated a number of immune-related genes in the pathogenesis of inflammatory bowel disease (IBD). Our recent genetic studies showed that RAC2 is associated with human IBD; however, its role in disease pathogenesis
Externí odkaz:
https://doaj.org/article/257e832d2d974e3eba67135d104855d0
Autor:
Valerie Trinidad Ramirez, Ingrid Brust-Mascher, Mariana Barboza Gardner, Jessica A. Sladek, Melanie G. Gareau, Colin Reardon
Publikováno v:
The Journal of Immunology. 202:66.16-66.16
The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial
Autor:
Ulrika Beitnere, Brayan Vilanova-Cuevas, Sarah G. Christian, Clint Taylor, Elizabeth L. Berg, Nycole A. Copping, Scott V. Dindot, Jill L. Silverman, Mélanie G. Gareau, David J. Segal
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT A large subset of patients with Angelman syndrome (AS) suffer from concurrent gastrointestinal (GI) issues, including constipation, poor feeding, and reflux. AS is caused by the loss of ubiquitin ligase E3A (UBE3A) gene expression in the bra
Externí odkaz:
https://doaj.org/article/603c826aee6f48c298a9ce88f28aaa34
Autor:
Mélanie G. Gareau
Publikováno v:
mSystems, Vol 7, Iss 4 (2022)
ABSTRACT The gut microbiota is increasingly being found to contribute to the etiology and severity of multiple diseases, including within the central nervous system (CNS). This microbiota-gut-brain (MGB) axis facilitates communication between gut mic
Externí odkaz:
https://doaj.org/article/81e662c5a16941e08b1219b1cbfe523e
Autor:
Matteo M Pusceddu, Melanie G Gareau
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-8 (2018)
Abstract Background Visceral pain is a complex and heterogeneous disorder, which can range from the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral pain involves the spinal cord as well as higher order brai
Externí odkaz:
https://doaj.org/article/2103b12d4ca2475abb4a82e4b0b55f95
Autor:
Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner, Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007719 (2019)
The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial
Externí odkaz:
https://doaj.org/article/08cee2719d0f40789cb49ce1ac73fef5