Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Melanie Föcking"'
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 39, Iss , Pp 100809- (2024)
Externí odkaz:
https://doaj.org/article/56147717bd8f4a76837bef96c58d8d16
Autor:
Eleftheria Kodosaki, Colm Healy, Jonah F. Byrne, Melanie Föcking, Mary Cannon, Diana O. Perkins, David Cotter, Meike Heurich
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 10, Iss , Pp 100097- (2024)
The complement system is an important part of the innate immune system and plays a key role in inflammatory processes. Concentrations of complement activation fragments in plasma are markers of systemic activation and have been found to be altered in
Externí odkaz:
https://doaj.org/article/a007b24e7a66473eba225d625d9bf8e7
Autor:
Subash Raj Susai, Colm Healy, David Mongan, Meike Heurich, Jonah F. Byrne, Mary Cannon, Gerard Cagney, Kieran Wynne, Connie Markulev, Miriam R. Schäfer, Maximus Berger, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Rebekah Street, Andrew Thompson, Alison Ruth Yung, Barnaby Nelson, Patrick D. McGorry, Melanie Föcking, G. Paul Amminger, David Cotter
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) in early psychosis. The present study investigates the molecular mechanism of omega-3 PUFA-associated therapeutic effects in clinical high-risk
Externí odkaz:
https://doaj.org/article/ef015f3560c34a10bba31b92235544a1
Autor:
David Mongan, Subash Raj Susai, Melanie Föcking, Jonah F. Byrne, Stan Zammit, Mary Cannon, David R. Cotter
Publikováno v:
Mongan, D, Raj Susai, S, Föcking, M, Byrne, J F, Zammit, S, Cannon, M & Cotter, D R 2023, ' Associations between plasma inflammatory markers and psychotic disorder, depressive disorder and generalised anxiety disorder in early adulthood: a nested case-control study ', Brain, Behavior and Immunity, vol. 111, pp. 90-100 . https://doi.org/10.1016/j.bbi.2023.03.025
BackgroundLow-grade inflammation may occur in association with several mental disorders of early adulthood, though associations with markers of chronic inflammation such as soluble urokinase plasminogen activator receptor (suPAR) are less well-establ
Autor:
Subash Raj Susai, Melanie Föcking, David Mongan, Meike Heurich, Fiona Coutts, Alice Egerton, Tony Whetton, Inge Winter-van Rossum, Richard D Unwin, Thomas A Pollak, Mark Weiser, Marion Leboyer, Dan Rujescu, Jonah F Byrne, George W Gifford, Paola Dazzan, Nikolaos Koutsouleris, René S Kahn, David R Cotter, Philip McGuire
Publikováno v:
Schizophrenia Bulletin.
Background and HypothesisTreatment response to specific antipsychotic medications is difficult to predict on clinical grounds alone. The current study hypothesizes that the baseline complement pathway activity predicts the treatment response and inve
Autor:
David Cotter, Miriam R. Schäfer, G. Paul Amminger, Maximus Berger, Monika Schlögelhofer, Nilufar Mossaheb, Subash Raj Susai, Stefan Smesny, Colm Healy, Connie Markulev, Andrew Thompson, Ian B. Hickie, Anita Riecher-Rössler, Swapna Verma, Mary Cannon, Dorien H. Nieman, David Mongan, Alison R. Yung, Patrick D. McGorry, Eric Y.H. Chen, Merete Nordentoft, Lieuwe de Haan, Melanie Föcking, Gregor Berger, Barnaby Nelson
Publikováno v:
Brain, behavior, and immunity, 99, 147-156. Academic Press Inc.
Background There is increasing evidence that dysregulation of polyunsaturated fatty acids (FAs) mediated membrane function plays a role in the pathophysiology of schizophrenia. Even though preclinical findings have supported the anti-inflammatory pro
Publikováno v:
Molecular Psychiatry
Early identification and treatment significantly improve clinical outcomes of psychotic disorders. Recent studies identified protein components of the complement and coagulation systems as key pathways implicated in psychosis. These specific protein
Publikováno v:
Early Intervention in Psychiatry. 16:3-16
Aim: Among different types of poly unsaturated fatty acids, omega-3 fatty acids (FA) play a substantial role in brain development and functioning. This review was designed to evaluate and synthesize available evidence regarding omega-3 FAs and functi
Publikováno v:
Schizophrenia Research
Background There is renewed focus on the complement system in the pathogenesis of schizophrenia. In addition to providing aetiological insights, consistently dysregulated complement proteins in serum or plasma may have clinical utility as biomarkers.
Autor:
Subash Raj Susai, David Mongan, Colm Healy, Mary Cannon, Gerard Cagney, Kieran Wynne, Jonah F. Byrne, Connie Markulev, Miriam R. Schäfer, Maximus Berger, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y.H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Rebekah Street, Andrew Thompson, Alison Ruth Yung, Barnaby Nelson, Patrick D. McGorry, Melanie Föcking, G. Paul Amminger, David Cotter
Publikováno v:
Brain, behavior, and immunity, 103, 50-60. Academic Press Inc.
Raj Susai, Subash; Mongan, David; Healy, Colm; Cannon, Mary; Cagney, Gerard; Wynne, Kieran; Byrne, Jonah F; Markulev, Connie; Schäfer, Miriam R; Berger, Maximus; Mossaheb, Nilufar; Schlögelhofer, Monika; Smesny, Stefan; Hickie, Ian B; Berger, Gregor E; Chen, Eric Y H; de Haan, Lieuwe; Nieman, Dorien H; Nordentoft, Merete; Riecher-Rössler, Anita; ... (2022). Machine learning based prediction and the influence of complement-coagulation pathway proteins on clinical outcome: results from the NEURAPRO trial. Brain, behavior, and immunity, 103, pp. 50-60. Elsevier 10.1016/j.bbi.2022.03.013
Raj Susai, Subash; Mongan, David; Healy, Colm; Cannon, Mary; Cagney, Gerard; Wynne, Kieran; Byrne, Jonah F; Markulev, Connie; Schäfer, Miriam R; Berger, Maximus; Mossaheb, Nilufar; Schlögelhofer, Monika; Smesny, Stefan; Hickie, Ian B; Berger, Gregor E; Chen, Eric Y H; de Haan, Lieuwe; Nieman, Dorien H; Nordentoft, Merete; Riecher-Rössler, Anita; ... (2022). Machine learning based prediction and the influence of complement-coagulation pathway proteins on clinical outcome: results from the NEURAPRO trial. Brain, behavior, and immunity, 103, pp. 50-60. Elsevier 10.1016/j.bbi.2022.03.013
BACKGROUND Functional outcomes are important measures in the overall clinical course of psychosis and individuals at clinical high-risk (CHR), however, prediction of functional outcome remains difficult based on clinical information alone. In the fir