Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Melanie E. DeFord"'
Autor:
Christie M. Orschell, Todd C. Skaar, Melanie E. DeFord, Joel Ybe, Julie Driscol, Christine Drury, Lilith Reeves, Monte S. Willis, Jill L. Reiter, Jenna York, Rob Orr, Jeanette N. McClintick, Thomas G. Sors, Joe Hunt, Kenneth Cornetta, Anantha Shekhar
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Abstract Introduction: Access to cutting-edge technologies is essential for investigators to advance translational research. The Indiana Clinical and Translational Sciences Institute (CTSI) spans three major and preeminent universities, four large a
Externí odkaz:
https://doaj.org/article/8a64aa9550724731a7626ffb0846dd02
Autor:
Jenna York, Joel A. Ybe, Jeanette N. McClintick, Christie M. Orschell, Lilith Reeves, Kenneth Cornetta, Joe D. Hunt, Monte S. Willis, Thomas G. Sors, Jill L. Reiter, Julie Driscol, Todd C. Skaar, Melanie E. DeFord, Christine Drury, Anantha Shekhar, Rob Orr
Publikováno v:
Journal of Clinical and Translational Science
Introduction: Access to cutting-edge technologies is essential for investigators to advance translational research. The Indiana Clinical and Translational Sciences Institute (CTSI) spans three major and preeminent universities, four large academic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad1336b195f875adc47b10e0f7894cb
https://doi.org/10.1017/cts.2020.525
https://doi.org/10.1017/cts.2020.525
Autor:
Anantha Shekhar, Tammy J. Sajdyk, Mary E. Murray, Joe D. Hunt, Thomas G. Sors, Melanie E. DeFord, Scott C. Denne
Publikováno v:
Academic Medicine. 90:40-46
The trend in conducting successful biomedical research is shifting from individual academic labs to coordinated collaborative research teams. Teams of experienced investigators with a wide variety of expertise are now critical for developing and main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9578a113157aad2b64499f13a0703067
https://doi.org/10.1097/acm.0000000000000528
https://doi.org/10.1097/acm.0000000000000528
Autor:
Lizette Busquets, Mary Prorok, Hector Guillen, Francis J. Castellino, Melanie E. DeFord, Mark A. Suckow, Rudolph M. Navari
Publikováno v:
Tumor Biology. 27:36-42
Transcriptional profiling of APC(Min/+) mouse intestinal epithelial tissue has revealed that cathepsin E (catE) manifests high relative expression in adenomas and carcinomas relative to normal epithelium. Real-time RT-PCR data presented previously co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8f455ae4fdc43bdcd18ea63cc9f24e
https://doi.org/10.1159/000090154
https://doi.org/10.1159/000090154
Autor:
William P. Fay, Melanie E. DeFord, Lakshmi Mundada, Mary Prorok, Francis J. Castellino, Mariana Figuera
Publikováno v:
Journal of Biological Chemistry. 278:24421-24427
Streptokinase (SK) binds to plasminogen (Pg) to form a complex that converts substrate Pg to plasmin. Residues 1-59 of SK regulate its capacity to induce an active site in bound Pg by a nonproteolytic mechanism and to activate substrate Pg in a fibri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adeeeab8547b552fbf36f04a9439de53
https://doi.org/10.1074/jbc.m301825200
https://doi.org/10.1074/jbc.m301825200
Autor:
Zhong Liang, Julie A. Wilberding, Ivo Cornelissen, Francis J. Castellino, Melanie E. DeFord, Victoria A. Ploplis, Laura McLennan, Elliot D. Rosen
Publikováno v:
The American Journal of Pathology. 157:703-708
In addition to their well-known roles in hemostasis, fibrinogen (Fg) and fibrin (Fn) have been implicated in a number of other physiological and pathophysiological events. One of these involves the fibroproliferative response after acute lung injury,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a2924229f924a48ee54496ecd3e6a7
https://doi.org/10.1016/s0002-9440(10)64582-8
https://doi.org/10.1016/s0002-9440(10)64582-8
Autor:
Hilary Gray, Pamela A. Trail, Daniel Marti, Francis J. Castellino, Robert Kramer, Xavier Villarreal, Melanie E. DeFord, Miguel Llinás, Johann Schaller, Weidong-Richard Ji, Mohammad Eghtedarzadeh Kondri, Yuan Chang
Publikováno v:
The FASEB Journal. 12:1731-1738
Angiogenesis is a complex process that involves endothelial cell proliferation, migration, basement membrane degradation, and neovessel organization. Angiostatin, consisting of four homologous triple-disulfide bridged kringle domains, has previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a05d445d47acc7b49b0c53e63dd917
https://doi.org/10.1096/fasebj.12.15.1731
https://doi.org/10.1096/fasebj.12.15.1731
Autor:
Lizette, Busquets, Hector, Guillen, Melanie E, DeFord, Mark A, Suckow, Rudolph M, Navari, Francis J, Castellino, Mary, Prorok
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 27(1)
Transcriptional profiling of APC(Min/+) mouse intestinal epithelial tissue has revealed that cathepsin E (catE) manifests high relative expression in adenomas and carcinomas relative to normal epithelium. Real-time RT-PCR data presented previously co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f7381025d9fc0b1b82b52e3121f3985
https://pubmed.ncbi.nlm.nih.gov/16340248
https://pubmed.ncbi.nlm.nih.gov/16340248
Autor:
Matthew W. Feldman, Ivo Cornelissen, Francis J. Castellino, Zhong Liang, Julie A. Wilberding, Elliot D. Rosen, Melanie E. DeFord, Victoria A. Ploplis, Laura McLennan
Publikováno v:
Annals of the New York Academy of Sciences. 936
Bleomycin is an antineoplastic drug commonly used for the treatment of many carcinomas and lymphomas. Its toxic side effect on lung tissue is a major limitation to its use, with approximately 3-5% of patients affected. Although the number of affected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b057ca0ca74eca7c6317b5124b048c13
https://pubmed.ncbi.nlm.nih.gov/11460513
https://pubmed.ncbi.nlm.nih.gov/11460513
Autor:
Xavier Villarreal, Weidong-Richard Ji, Melanie E. DeFord, Hilary Gray, Laura G. Barrientos, Pamela A. Trail, Francis J. Castellino, Robert Kramer, Miguel Llinás
Publikováno v:
Biochemical and biophysical research communications. 247(2)
Angiogenesis is a multi-step process that includes endothelial cell proliferation, migration, basement membrane degradation, and new lumen organization. Angiostatin, an internal fragment of plasminogen comprising the first four triple disulfide-linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8c4a71078659253dd05a835142ce27
https://pubmed.ncbi.nlm.nih.gov/9642142
https://pubmed.ncbi.nlm.nih.gov/9642142