Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Melanie Doyle-Eisele"'
Autor:
C. Edwin Garner, Christopher J. Wegerski, Melanie Doyle-Eisele, Jacob D. McDonald, J. Michael Sanders, Benjamin C. Moeller, Suramya Waidyanatha
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 883-892 (2020)
2′,2′′′-Dithiobisbenzanilide (DTBBA) is a high-production-volume chemical used as a peptizing agent for rubber. The disposition and metabolism of [14C]DTBBA were determined in male and female rats and mice following oral (4, 40, or 400 mg/kg)
Externí odkaz:
https://doaj.org/article/ccfc7d63e08048ffa968a1f99f964164
Autor:
Aruni Jha, Melanie Doyle-Eisele, David Revelli, Trevor Carnelley, Douglas Barker, Shantha Kodihalli
Publikováno v:
Viruses, Vol 15, Iss 1, p 123 (2022)
Despite ongoing vaccination efforts to prevent SARS-CoV-2 infections, treatment tools are still necessary to address the ongoing COVID-19 pandemic. We report here that COVID-HIGIV, a human immunoglobulin product for treatment of COVID-19, provided a
Externí odkaz:
https://doaj.org/article/af78d50e8e77451e89da422f7f84f586
Autor:
Katherine M. Gott, Charles A. Potter, Melanie Doyle-Eisele, Yong Lin, Julie Wilder, Bobby R. Scott
Publikováno v:
Dose-Response, Vol 18 (2020)
US homeland security concerns regarding the potential misuse of some radiation sources used in radiobiological research, for example, cesium-137 ( 137 Cs), have resulted in recommendations by the National Research Council to conduct studies into repl
Externí odkaz:
https://doaj.org/article/800bcb4e5f4f413a8844d6104b0ae326
Autor:
Helen C Turner, Igor Shuryak, Waylon Weber, Melanie Doyle-Eisele, Dunstana Melo, Raymond Guilmette, Sally A Amundson, David J Brenner
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143815 (2015)
In the event of a dirty bomb scenario or an industrial nuclear accident, a significant dose of volatile radionuclides such as 137Cs and 90Sr may be dispersed into the atmosphere as a component of fallout and inhaled or ingested by hundreds and thousa
Externí odkaz:
https://doaj.org/article/48c746335f424aa1b16c7fa5fdf31fe7
Autor:
Chad R. Blystone, Suramya Waidyanatha, Melanie Doyle-Eisele, Jacob D. McDonald, At Lee T.D. Watson, Edwin Garner, Benjamin C. Moeller
Publikováno v:
Xenobiotica. :1-14
Ethylene glycol 2-ethylhexyl ether (EGEHE) is a solvent used in a variety of applications.We report disposition and metabolism of EGEHE following a single gavage or dermal administration of 50, 150...
Autor:
J. Michael Sanders, Jacob D. McDonald, Benjamin C. Moeller, Suramya Waidyanatha, Melanie Doyle-Eisele, C. Edwin Garner, Christopher J. Wegerski
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 883-892 (2020)
Toxicology Reports, Vol 7, Iss, Pp 883-892 (2020)
Highlights • 2′,2′′′-Dithiobisbenzanilide (DTBBA) is a chemical used as a peptizing agent for rubber. • Humane exposure to DTBBA is possible via oral and dermal routes. • DTBBA is well-absorbed in rodents following oral and dermal admin
Autor:
Simon Authier, Francis Herodin, Melanie Doyle-Eisele, Michel Drouet, Karla D. Thrall, Jean-Marc Bertho, Ann M. Farese, Thomas J. MacVittie
Publikováno v:
Health physics. 121(4)
Medical countermeasure development under the US Food and Drug Administration animal rule requires validated animal models of acute radiation effects. The key large animal model is the non-human primate, rhesus macaque. To date, only the rhesus macaqu
Autor:
Christopher J. Wegerski, Jacob D. McDonald, Suramya Waidyanatha, Barry S. McIntyre, C. Edwin Garner, Melanie Doyle-Eisele, Esra Mutlu
Publikováno v:
Xenobiotica
1. 2-Hydroxy-4-methoxybenzophenone (HMB) is a common ingredient in personal care products and used as an UV stabilizer. In these studies, disposition and metabolism of [(14)C]HMB in rats and mice was assessed following single gavage administration (1
Autor:
Kim Paulson, Derek A. Hamilton, Waylon Weber, Christy M. Magcalas, Nitin Bangera, Robert Raulli, Judith Laney, Andrew P. Gigliotti, Efrain Garcia, Jeffrey D. Lewine, Jacob D. McDonald, Melanie Doyle-Eisele
Publikováno v:
NeuroToxicology. 69:37-46
Rats poisoned with sarin enter into ahyper-cholinergic crisis characterized by excessive salivation, respiratory distress, tremors, seizures, and death. Through the use of rescue medications and an anticonvulsant, death can be avoided in many animals
Autor:
AtLee T D, Watson, Benjamin C, Moeller, Melanie, Doyle-Eisele, Edwin, Garner, Chad R, Blystone, Jacob D, McDonald, Suramya, Waidyanatha
Publikováno v:
Xenobiotica
1. Ethylene glycol 2-ethylhexyl ether (EGEHE) is a solvent used in a variety of applications. 2. We report disposition and metabolism of EGEHE following a single gavage or dermal administration of 50, 150 or 500 mg/kg [(14)C]EGEHE in rats and mice an