Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Melanie De La Cruz"'
Autor:
Melanie De La Cruz, Esteban G. Burchard, Leah L. Lagpacan, Kathleen M. Giacomini, Elaine J. Carlson, Douglas Stryke, Travis R. Taylor, Claire M. Brett, Conrad C. Huang, Thomas J. Urban, Thomas E. Ferrin, Lara M. Mangravite, Susan J. Johns, Michiko Kawamoto, Andrew R. Erdman, Richard A. Castro, Wendy Chan
Publikováno v:
American Journal of Physiology-Renal Physiology. 290:F905-F912
The human organic anion transporter, OAT3 ( SLC22A8), plays a critical role in renal drug elimination, by mediating the entry of a wide variety of organic anions, including a number of commonly used pharmaceuticals, into the renal proximal tubular ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ce746a38b55d7cf3a0f5fe68b0bdab
https://doi.org/10.1152/ajprenal.00272.2005
https://doi.org/10.1152/ajprenal.00272.2005
Autor:
Kathleen M. Giacomini, Maya K. Leabman, Melanie De La Cruz, Thomas E. Ferrin, Joseph DeYoung, Elaine J. Carlson, Travis R. Taylor, Susan J. Johns, Deanna L. Kroetz, Ira Herskowitz, Conrad C. Huang, Andrew G. Clark, Neil Risch, Thomas J. Urban, Michiko Kawamoto, Doug Stryke
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5896-5901
Membrane transporters maintain cellular and organismal homeostasis by importing nutrients and exporting toxic compounds. Transporters also play a crucial role in drug response, serving as drug targets and setting drug levels. As part of a pharmacogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21305b541a21a057b49a96fface9beb
https://doi.org/10.1073/pnas.0730857100
https://doi.org/10.1073/pnas.0730857100
Autor:
Travis R. Taylor, Wendy Chan, Michiko Kawamoto, Richard A. Castro, Susan J. Johns, Esteban G. Burchard, Tomoe Fujita, Doug Stryke, Elaine J. Carlson, Ira Herskowitz, Chaline Brown, Maya K. Leabman, Kathleen M. Giacomini, Leah L. Lagpacan, Cilaire M. Brett, Andrew R. Erdman, Yan Shu, Melanie De La Cruz, Thomas E. Ferrin, Conrad C. Huang, Deanna L. Kroetz, Thomas J. Urban
Publikováno v:
Pharmacological reviews. 58(1)
Category: genotype Project: Pharmacogenetics of Membrane Transporters [Table 1][1] provides HUGO Gene Nomenclature Committee (HGNC) symbols, PharmGKB submission URLs, submission dates, and release dates. [Table 2][2] provides HGNC symbols, HGNC names
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a763fec6d1c6b31c4279c9c395d5d64
https://pubmed.ncbi.nlm.nih.gov/16507878
https://pubmed.ncbi.nlm.nih.gov/16507878
Autor:
Susan J. Johns, Conrad C. Huang, Thomas E. Ferrin, Leah L. Lagpacan, Melanie De La Cruz, Travis R. Taylor, Ryan P. Owen, Doug Stryke, Kathleen M. Giacomini, Michiko Kawamoto
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 34(1)
The equilibrative nucleoside transporter 2 (ENT2; SLC29A2) is a bidirectional transporter that is involved in the disposition of naturally occurring nucleosides as well as a variety of anticancer and antiviral nucleoside analogs. The goal of the curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded39b13df3d8ac1c0c2c26bb4884958
https://pubmed.ncbi.nlm.nih.gov/16214850
https://pubmed.ncbi.nlm.nih.gov/16214850
Autor:
Doug Stryke, Chaline Brown, Chung-Wen Chen, Melanie De La Cruz, Kathleen M. Giacomini, Michiko Kawamoto, Travis R. Taylor, Tomoe Fujita, Thomas E. Ferrin, Esteban G. Burchard, Richard A. Castro, Elaine J. Carlson, Maya K. Leabman, Claire M. Brett, Susan J. Johns, Conrad C. Huang, Kazumi Fujita, Emil T. Lin
Publikováno v:
Pharmacogenetics and genomics. 15(4)
The organic anion transporter, OAT1 (SLC22A6), plays a role in the renal elimination of many drugs and environmental toxins. The goal of this study was to identify and functionally characterize OAT1 variants as a first step towards understanding whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4041d93965ae033c896719580da690
https://pubmed.ncbi.nlm.nih.gov/15864112
https://pubmed.ncbi.nlm.nih.gov/15864112
Autor:
Richard A. Castro, Esteban G. Burchard, Susan J. Johns, Kathleen M. Giacomini, Robert H. Edwards, Chaline Brown, Marco D. Sorani, Wendy Chan, Michiko Kawamoto, Ilaria Badagnani, Melanie De La Cruz, Travis R. Taylor, Ira Herskowitz, Thomas E. Ferrin, Doug Stryke, Conrad C. Huang, Elaine J. Carlson, Deanna L. Kroetz
Publikováno v:
Pharmacological Reviews. 58:5-6
Category: genotype Project: Pharmacogenetics of Membrane Transporters [Table 1][1] provides HUGO Gene Nomenclature Committee (HGNC) symbols, PharmGKB submission URLs, submission dates, and release dates. [Table 2][2] provides HGNC symbols, HGNC names
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c89f0cf1452565c5ba07129c4077408
https://doi.org/10.1124/pr.58.1.3
https://doi.org/10.1124/pr.58.1.3