Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melanie D. Schaffler"'
Publikováno v:
Current Psychiatry Reports.
Autor:
Melanie D Schaffler, Micah Johnson, Ben Hing, Paul Kahler, Ian Hultman, Sanvesh Srivastava, Justin Arnold, Julie N Blendy, Rainbo Hultman, Ishmail Abdus-Saboor
Publikováno v:
SSRN Electronic Journal.
Social touch can act as a stress buffer, reducing behavioral and physiological responses to stressful scenarios. However, skin-brain touch pathways that promote stress resilience remain unknown. Here, we show that mice with an early life genetic abla
Autor:
Leah J. Elias, Isabella K. Succi, Melanie D. Schaffler, William Foster, Mark A. Gradwell, Manon Bohic, Akira Fushiki, Aman Upadhyay, Lindsay L. Ejoh, Ryan Schwark, Rachel Frazer, Brittany Bistis, Jessica E. Burke, Victoria Saltz, Jared E. Boyce, Anissa Jhumka, Rui M. Costa, Victoria E. Abraira, Ishmail Abdus-Saboor
Publikováno v:
Cell. 186:577-590.e16
Autor:
Manon Bohic, William H. Foster, Isabella Succi, Lindsay Ejoh, Melanie D. Schaffler, Victoria E. Abraira, Leah J. Middleton, Mark A Gradwell, Ishmail Abdus-Saboor
Pleasurable touch during social behavior is the key to building familial bonds and meaningful connections. One form of social touch occurs during sexual encounters. Although sexual behavior is initiated in part by touch, and touch is ongoing througho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1379a1e2ed2d23ccd8e72719fea0fb
https://doi.org/10.1101/2021.09.22.461355
https://doi.org/10.1101/2021.09.22.461355
Publikováno v:
Current Psychiatry Reports
Purpose of Review This review aims to summarize the current body of behavioral, physiological, and molecular knowledge concerning tactile sensitivity in autism spectrum disorder (ASD), with a focus on recent studies utilizing rodent models. Recent Fi
Autor:
Axel Visel, Michael C. Pride, Konstantinos Zarbalis, Diane E. Dickel, Tyler W. Stradleigh, Nycole A. Copping, Linda Su-Feher, Gaurav Kaushik, Veena Afzal, Alexander Nord, Rinaldo Catta-Preta, Len A. Pennacchio, Melanie D. Schaffler, Jacqueline N. Crawley, Ingrid Plajzer-Frick, A. Ayanna Wade, M. Asrafuzzaman Riyadh, Shreya Louis, Jacob Ellegood, Iva Zdilar, Brandon J. Mannion, Andrea Gompers, Jill L. Silverman, Jason P. Lerch
Publikováno v:
Gompers, AL; Su-Feher, L; Ellegood, J; Copping, NA; Riyadh, MA; Stradleigh, TW; et al.(2017). Germline Chd8 haploinsufficiency alters brain development in mouse. Nature Neuroscience, 20(8), 1062-1073. doi: 10.1038/nn.4592. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/0ck9n78k
Nature neuroscience, vol 20, iss 8
Nature neuroscience, vol 20, iss 8
© 2017 Nature America, Inc., part of Springer Nature. All rights reserved. The chromatin remodeling gene CHD8 represents a central node in neurodevelopmental gene networks implicated in autism. We examined the impact of germline heterozygous framesh
Autor:
Melanie D. Schaffler, Arnold J. Heynen, Mark F. Bear, Jacqueline N. Crawley, Tatiana M. Kazdoba, Laura J. Stoppel, Anthony R. Preza
Publikováno v:
Nature
Neuropsychopharmacology
Neuropsychopharmacology
Human chromosome 16p11.2 microdeletion is among the most common gene copy number variations (CNVs) known to confer risk for intellectual disability (ID) and autism spectrum disorder (ASD) and affects an estimated 3 in 10 000 people. Caused by a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621e57ff53fff628a20b45446f4fd515
https://hdl.handle.net/1721.1/126513
https://hdl.handle.net/1721.1/126513
Autor:
Nycole A. Copping, Iva Zdilar, Diane E. Dickel, Gaurav Kaushik, M. Asrafuzzaman Riyadh, Melanie D. Schaffler, Brandon J. Mannion, Michael C. Pride, Andrea Gompers, Linda Su-Feher, Ingrid Plajzer-Frick, Jill L. Silverman, Jason P. Lerch, Jacob Ellegood, Jacqueline N. Crawley, Len A. Pennacchio, Veena Afzal, Konstantinos Zarbalis, Axel Visel, Tyler W. Stradleigh, Alexander Nord
SummaryThe chromatin remodeling gene CHD8 represents a central node in early neurodevelopmental gene networks implicated in autism. We examined the impact of heterozygous germline Chd8 mutation on neurodevelopment in mice. Network analysis of neurode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3ed720e832cf1a377fd4c194077268
https://escholarship.org/uc/item/8jr5v1gp
https://escholarship.org/uc/item/8jr5v1gp
Autor:
Nycole A. Copping, Jill L. Silverman, Beth L. Onaga, Nathalie Buscher, Gillian M. Foley, Melanie D. Schaffler, Elizabeth L. Berg, Mu Yang
Publikováno v:
Neuroscience. 345
SHANK3 is a synaptic scaffolding protein localized in the postsynaptic density and has a crucial role in synaptogenesis and neural physiology. Deletions and point mutations in SHANK3 cause Phelan-McDermid Syndrome (PMS), and have also been implicated