Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melanie D. E. Allington"'
Autor:
Rebecca L. Roberts, Bruce A. Chapman, Michael J. Burt, Melanie D. E. Allington, Chris Frampton, Philippa Shirley, Judith A. Collett, Richard B. Gearry, Murray L. Barclay, Martin A. Kennedy
Publikováno v:
Inflammatory Bowel Diseases. 13:1220-1227
NOD2 mutations are associated with Crohn's disease (CD) in Caucasian clinic-based cohorts. Data from population-based cohorts are limited. Clinic-based studies may overestimate this association. Genotype-phenotype relationships are yet to be assessed
Autor:
Helen Morrin, Richard B. Gearry, Rebecca L. Roberts, Melanie D. E. Allington, Bridget A. Robinson, Frank A. Frizelle
Publikováno v:
Cancer Research. 66:2532-2535
The caspase recruitment domain-containing protein 15 (CARD15) plays a crucial role in mediating the innate immune response. Mutations within this protein have been shown to be independent risk factors for the development of Crohn's disease in Caucasi
Autor:
Elisabeth Wells, Roger T. Mulder, Martin A. Kennedy, Allison L. Miller, Melanie D. E. Allington, Peter R. Joyce, Douglas Sellman, Geraldine R. Rogers, Robin J. Olds
Publikováno v:
American Journal of Medical Genetics. :95-98
Novelty Seeking (NS) is a human personality trait in which impulsive, exploratory, and thrill-seeking behaviors are displayed. Dopaminergic genes have been prime candidates in the search for the genetic factors underlying NS because of the central ro
Autor:
Geraldine R. Rogers, Martin A. Kennedy, Peter R. Joyce, Melanie D. E. Allington, Mark Hughes, Dylan M. Glubb, Patrick C McHugh
Publikováno v:
Acta neuropsychiatrica. 20(6)
Objective:The mechanism of action of antidepressant drugs is not fully understood. Application of genomic methods enables the identification of biochemical pathways that are regulated by antidepressants, and this may provide novel clues to the molecu