Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Melanie D Mark"'
Autor:
Zohre Azimi, Ruxandra Barzan, Katharina Spoida, Tatjana Surdin, Patric Wollenweber, Melanie D Mark, Stefan Herlitze, Dirk Jancke
Publikováno v:
eLife, Vol 9 (2020)
Controlling gain of cortical activity is essential to modulate weights between internal ongoing communication and external sensory drive. Here, we show that serotonergic input has separable suppressive effects on the gain of ongoing and evoked visual
Externí odkaz:
https://doaj.org/article/d39f0964e4534c70a3e4975928c8dd43
Autor:
Ruxandra Barzan, Beyza Bozkurt, Mohammadreza M. Nejad, Sandra T. Süß, Tatjana Surdin, Hanna Böke, Katharina Spoida, Zohre Azimi, Michelle Grömmke, Dennis Eickelbeck, Melanie D. Mark, Lennard Rohr, Ida Siveke, Sen Cheng, Stefan Herlitze, Dirk Jancke
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Response gain is a crucial means by which modulatory systems control the impact of sensory input. In the visual cortex, the serotonergic 5-HT2A receptor is key in such modulation. However, due to its expression across different cell types an
Externí odkaz:
https://doaj.org/article/4677b8bf48824430a69725e8821ff54c
Autor:
Melanie D Mark, Marcel Donner, Dennis Eickelbeck, Jennifer Stepien, Minou Nowrousian, Ulrich Kück, Frank Paris, Jens Hellinger, Stefan Herlitze
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0198765 (2018)
Bioluminescence is a fascinating phenomenon and can be found in many different organisms including fish. It has been suggested that bioluminescence is used for example for defense, prey attraction, and for intraspecific communication to attract for e
Externí odkaz:
https://doaj.org/article/a7d0c2679384469097728e5c1f53a8a8
Autor:
Jens Hellinger, Peter Jägers, Marcel Donner, Franziska Sutt, Melanie D Mark, Budiono Senen, Ralph Tollrian, Stefan Herlitze
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170489 (2017)
Bioluminescence is a fascinating phenomenon occurring in numerous animal taxa in the ocean. The reef dwelling splitfin flashlight fish (Anomalops katoptron) can be found in large schools during moonless nights in the shallow water of coral reefs and
Externí odkaz:
https://doaj.org/article/24a202911130469eab07654f2ce644c6
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study emphasizes the benefits of open-source software such as DeepLabCut (DLC) and R to automate, customize and enhance data analysis of motor behavior. We recorded 2 different spinocerebellar ataxia type 6 mouse models while performing
Externí odkaz:
https://doaj.org/article/60279aa31a3e436081ba63691f9b13d1
Autor:
Wolfgang Kruse, Martin Krause, Janna Aarse, Melanie D Mark, Denise Manahan-Vaughan, Stefan Herlitze
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105589 (2014)
The firing patterns of cerebellar Purkinje cells (PCs), as the sole output of the cerebellar cortex, determine and tune motor behavior. PC firing is modulated by various inputs from different brain regions and by cell-types including granule cells (G
Externí odkaz:
https://doaj.org/article/b41ba23f36714ede80d9ba5ecbe8e962
Autor:
Katrina E. Deane, Ruslan Klymentiev, Jennifer Heck, Melanie D. Mark, Frank W. Ohl, Martin Heine, Max F. K. Happel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionThe emergent coherent population activity from thousands of stochastic neurons in the brain is believed to constitute a key neuronal mechanism for salient processing of external stimuli and its link to internal states like attention and p
Externí odkaz:
https://doaj.org/article/11aba9cca4d2494fa89ba6d3e032043d
Autor:
Tatjana Surdin, Bianca Preissing, Lennard Rohr, Michelle Grömmke, Hanna Böke, Maike Barcik, Zohre Azimi, Dirk Jancke, Stefan Herlitze, Melanie D. Mark, Ida Siveke
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105828- (2023)
Summary: Neuronal plasticity underlying cerebellar learning behavior is strongly associated with type 1 metabotropic glutamate receptor (mGluR1) signaling. Activation of mGluR1 leads to activation of the Gq/11 pathway, which is involved in inducing s
Externí odkaz:
https://doaj.org/article/7b7d692bca43476ebd4c71542d3697e2
Autor:
Raziye Karapinar, Jan Claudius Schwitalla, Dennis Eickelbeck, Johanna Pakusch, Brix Mücher, Michelle Grömmke, Tatjana Surdin, Thomas Knöpfel, Melanie D. Mark, Ida Siveke, Stefan Herlitze
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and
Externí odkaz:
https://doaj.org/article/cd6b728c8c2a41f6902c7cf1ab408a53
Autor:
Adam Fekete, Yukihiro Nakamura, Yi-Mei Yang, Stefan Herlitze, Melanie D. Mark, David A. DiGregorio, Lu-Yang Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The mechanisms underlying synaptic heterogeneity of neurotransmission at mature calyx synapses remain unclear. Here, authors identify two morphological modules that have distinct topology of calcium channel clusters and spatial coupling distance to s
Externí odkaz:
https://doaj.org/article/342e2fb457a34f4ab2812f5d3c07851d