Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melanie Ceci"'
Autor:
Laura Israël, Anton Glück, Marjorie Berger, Marine Coral, Melanie Ceci, Adeline Unterreiner, Joëlle Rubert, Maureen Bardet, Stefanie Ginster, Alexandra M. Golding-Ochsenbein, Kea Martin, Thomas Hoyler, Thomas Calzascia, Grazyna Wieczorek, Rainer Hillenbrand, Stéphane Ferretti, Enrico Ferrero, Frédéric Bornancin
Publikováno v:
Oncogenesis, Vol 10, Iss 4, Pp 1-11 (2021)
Abstract CARD-CC complexes involving BCL10 and MALT1 are major cellular signaling hubs. They govern NF-κB activation through their scaffolding properties as well as MALT1 paracaspase function, which cleaves substrates involved in NF-κB regulation.
Externí odkaz:
https://doaj.org/article/1303cd00d0204bfd910f8215d77d013f
Autor:
Stuart Hawtin, Cédric André, Géraldine Collignon-Zipfel, Simone Appenzeller, Bettina Bannert, Lea Baumgartner, Damian Beck, Claudia Betschart, Thomas Boulay, Hermine I. Brunner, Melanie Ceci, Jonathan Deane, Roland Feifel, Enrico Ferrero, Diego Kyburz, Frederique Lafossas, Pius Loetscher, Christina Merz-Stoeckle, Pierre Michellys, Barbara Nuesslein-Hildesheim, Friedrich Raulf, James S. Rush, Giulia Ruzzante, Thomas Stein, Samantha Zaharevitz, Grazyna Wieczorek, Richard Siegel, Peter Gergely, Tamas Shisha, Tobias Junt
Publikováno v:
Cell Reports Medicine. 4:101036
Autor:
Giulio Macchiarella, Vanessa Cornacchione, Celine Cojean, Julia Riker, Yichen Wang, Helene Te, Melanie Ceci, Johann E. Gudjonsson, Swann Gaulis, Jean François Goetschy, Audrey Wollschlegel, Stephanie K. Gass, Sofia Oetliker-Contin, Barbara Wettstein-Ling, Dirk J. Schaefer, Pascale Meschberger, Roland de Roche, Rik Osinga, Grazyna Wieczorek, Ulrike Naumann, Joachim C.U. Lehmann, Anna Schubart, Andreas Hofmann, Lukas Roth, Edwin F. Florencia, Christian Loesche, Elisabetta Traggiai, Alexandre Avrameas, Errol P. Prens, Till A. Röhn, Ben Roediger
Publikováno v:
Journal of Investigative Dermatology, 143(2), 273-283.e12. Nature Publishing Group
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurring suppurating lesions of the intertriginous areas, resulting in a substantial impact on patients’ QOL. HS pathogenesis remains poorly understood. An autoi
Autor:
Maurane Henry, Meike Hamburger, Nadja Mamber, Celine Cojean, Katriona McMichael, Grazyna Wieczorek, Melanie Ceci, Marinette Erard, Marc Bigaud, Celine Texier, James S. Rush, Catherine Afatsawo, Sabina Pfister
Publikováno v:
Annals of the Rheumatic Diseases. 78:974-978
ObjectiveTo examine the role of CD40–CD154 costimulation and effects of therapeutic pathway blockade in the non-obese diabetic (NOD/ShiLtJ) model of Sjögren’s syndrome (SS).MethodsWe assessed leucocyte infiltration in salivary glands (SGs) from
Autor:
Marine Coral, Marjorie Berger, Melanie Ceci, Grazyna Wieczorek, Thomas Calzascia, Kea Martin, Stefanie Ginster, Enrico Ferrero, Adeline Unterreiner, Frédéric Bornancin, Alexandra M. Golding-Ochsenbein, Stephane Ferretti, Thomas Hoyler, Anton Glück, Joëlle Rubert, Maureen Bardet, Laura Israel, Rainer Hillenbrand
Publikováno v:
Oncogenesis
Oncogenesis, Vol 10, Iss 4, Pp 1-11 (2021)
Oncogenesis, Vol 10, Iss 4, Pp 1-11 (2021)
CARD-CC complexes involving BCL10 and MALT1 are major cellular signaling hubs. They govern NF-κB activation through their scaffolding properties as well as MALT1 paracaspase function, which cleaves substrates involved in NF-κB regulation. In human
Autor:
Philip Jarvis, Edward Khokhlovich, Irina Koroleva, Birgit Aigner, Marie-Anne Valentin, Dhavalkumar D. Patel, Gerard Bruin, Melanie Ceci, Grazyna Wieczorek, Frank Kolbinger, Frank Sinner, Christian Loesche
Publikováno v:
Advances in Precision Medicine. 1
Psoriasis is a well characterized interleukin (IL)-17A-driven skin disease with neutrophil infiltration and epidermal hyperkeratosis. Several biomarkers, most prominently β-defensin-2 (BD-2), have been identified using local and systemic invasive me
Autor:
L. Haeberli, Pascal Espie, L. Roth, R. Apolloni, Grazyna Wieczorek, M. Audet, Dhavalkumar D. Patel, Reto Baumgartner, A. Kunkler, Nathalie Stuber, Christoph Heusser, James S. Rush, Denise Sickert, Roger Grau, J. Munz, Melanie Ceci, Christian Bruns, D. Ristig, Francisco Cordoba, G. Robert, A. Cattini, M. Erard, Martin A. Schneider
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15(11)
CD40-CD154 pathway blockade prolongs renal allograft survival in nonhuman primates (NHPs). However, antibodies targeting CD154 were associated with an increased incidence of thromboembolic complications. Antibodies targeting CD40 prolong renal allogr
Autor:
Christian Kohler, Melanie Ceci, Aileen S. Wrynn, Veska Uzunova, Doncho P. Uzunov, Anu Kinnunen
Publikováno v:
European Journal of Pharmacology. 486:31-34
Olfactory bulbectomy is one of the most validated models of depression. We demonstrate that bilateral removal of the olfactory bulbs in rats produced a significant decline of allopregnanolone content in a select cerebrocortical area which was reverse
Publikováno v:
Brain research. 976(1)
Allopregnanolone (ALLO) is one of the most potent positive endogenous allosteric modulators of the type A gamma-aminobutyric acid (GABA(A)) receptors. While the robust anxiolytic profile of ALLO has been extensively characterized in rodents and its a