Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Melanie C. Audette"'
Publikováno v:
Journal of Perinatology. 42:91-96
To evaluate the diagnostic and screening utility of Kleihauer–Betke (KB) testing as a triage tool in predicting adverse fetal outcomes associated with fetomaternal hemorrhage (FMH). Single center retrospective cohort study evaluated a primary compo
Autor:
Rory Windrim, Melanie C. Audette, Sergio Carmona, Atif Syed, John Kingdom, John Snelgrove, Sebastian R. Hobson, Kelsey McLaughlin, Nir Melamed
Publikováno v:
Hypertension. 77:2057-2065
There is little evidence evaluating angiogenic growth factor testing in real-world obstetric settings. This investigation evaluated maternal and perinatal pregnancy outcomes associated with maternal PlGF (placental growth factor) levels in real-world
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178056 (2017)
BACKGROUND:Small ubiquitin-like modifiers (SUMOs) conjugate to proteins post-translationally, thereby affecting target localization, activity and stability. Functional SUMO family members identified in the human placenta include SUMO-1 to SUMO-3, whi
Externí odkaz:
https://doaj.org/article/a681316cfdfb41aeb8354285fcf77c8f
Autor:
Enrrico Bloise, Manzerul Bhuiyan, Melanie C Audette, Sophie Petropoulos, Mohsen Javam, William Gibb, Stephen G Matthews
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65728 (2013)
Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp--Abcb1a/b) and breast cancer resistance protein (BCRP--Abcg2). This potentially impairs fetal protection against harmful factors in the maternal circu
Externí odkaz:
https://doaj.org/article/b8966366a81a4212ba2df6f1c8936517
Publikováno v:
The Journal of Physiology. 596:1587-1600
KEY POINTS The post-translational modification of target proteins by SUMOylation occurs in response to stressful stimuli in a variety of organ systems. Small ubiquitin-like modifier (SUMO) isoforms 1-4 have recently been identified in the human place
Publikováno v:
Journal of Obstetrics and Gynaecology Canada. 43:1145-1152.e1
Placental growth factor (PlGF) levels are lower at delivery in pregnancies with preeclampsia or fetuses small for gestational age (SGA). These obstetrical complications are typically mediated by placental dysfunction, most commonly related to the spe
Publikováno v:
Placenta. 112:e43
Autor:
Emily Wright, Sarah Keating, Xiang Y. Ye, Stephen J. Lye, Barry Hoffman, Prakesh S. Shah, Melanie C. Audette, John Kingdom
Publikováno v:
Obstetrics & Gynecology. 130:1112-1120
Objective To evaluate the disease burden of placental maternal vascular malperfusion pathology in a low-risk nulliparous population and test the hypothesis that a multiparameter model in the second trimester can predict maternal vascular malperfusion
Publikováno v:
Canadian Journal of Cardiology. 37:e7