Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Melanie C MacNicol"'
Autor:
Jewel Banik, Ana Rita Silva Moreira, Juchan Lim, Sophia Tomlinson, Linda L. Hardy, Alex Lagasse, Anessa Haney, Meghan R. Crimmins, Ulrich Boehm, Angela K. Odle, Melanie C. MacNicol, Gwen V. Childs, Angus M. MacNicol
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The pituitary functions as a master endocrine gland that secretes hormones critical for regulation of a wide variety of physiological processes including reproduction, growth, metabolism and stress responses. The distinct hormone-producing c
Externí odkaz:
https://doaj.org/article/367dcc30f1c442de93a8c3febc716b13
Autor:
Alicja Urbaniak, Megan R. Reed, Daniel Fil, Anika Moorjani, Sarah Heflin, Michał Antoszczak, Michał Sulik, Adam Huczyński, Michalina Kupsik, Robert L. Eoff, Melanie C. MacNicol, Timothy C. Chambers, Angus M. MacNicol
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111815- (2021)
Breast cancer remains one of the leading cancers among women. Cancer stem cells (CSCs) are tumor-initiating cells which drive progression, metastasis, and reoccurrence of the disease. CSCs are resistant to conventional chemo- and radio-therapies and
Externí odkaz:
https://doaj.org/article/8f0fa178769f44c6a5f9775fcc5dbcfa
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The mechanisms that mediate plasticity in pituitary function have long been a subject of vigorous investigation. Early studies overcame technical barriers and challenged conceptual barriers to identify multipotential and multihormonal cell population
Externí odkaz:
https://doaj.org/article/7a60480762554d2a92f38774b60a0424
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3312 (2021)
The proper expression of gonadotropin-releasing hormone receptors (GnRHRs) by pituitary gonadotropes is critical for maintaining maximum reproductive capacity. GnRH receptor expression must be tightly regulated in order to maintain the normal pattern
Externí odkaz:
https://doaj.org/article/e0d211d958b644f79fc339e83b9043e7
Autor:
Angela K. Odle, Noor Akhter, Mohsin M. Syed, Melody L. Allensworth-James, Helen Beneš, Andrea I. Melgar Castillo, Melanie C. MacNicol, Angus M. MacNicol, Gwen V. Childs
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2018)
The adipokine leptin signals the body’s nutritional status to the brain, and particularly, the hypothalamus. However, leptin receptors (LEPRs) can be found all throughout the body and brain, including the pituitary. It is known that leptin is permi
Externí odkaz:
https://doaj.org/article/aa3d92d26f8d4d89974fcf1b93f185fa
Autor:
Melanie C. MacNicol, Chad E. Cragle, Karthik Arumugam, Bruno Fosso, Graziano Pesole, Angus M. MacNicol
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1580-1599 (2015)
Regulated mRNA translation plays a key role in control of cell cycle progression in a variety of physiological and pathological processes, including in the self-renewal and survival of stem cells and cancer stem cells. While targeting mRNA translatio
Externí odkaz:
https://doaj.org/article/7dc246b5e7a04c0cbd6c3137b227ebb8
Autor:
Robert L. Eoff, Melanie C. MacNicol, Angus M. MacNicol, Michał Sulik, Adam Huczyński, Michał Antoszczak, Megan R. Reed, Timothy C. Chambers, Alicja Urbaniak
Publikováno v:
Cancer Research. 81:PS18-46
Breast cancer remains one of the leading cancers among women and an estimated 90% of breast cancer deaths are due to metastasis. Cancer stem cells (CSCs) are a sub-population of cancer cells which are responsible for its initiation, progression and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d27a5916773cc1da4bb543820233cc
https://doi.org/10.1158/1538-7445.sabcs20-ps18-46
https://doi.org/10.1158/1538-7445.sabcs20-ps18-46
Autor:
Melanie C. MacNicol, Melody Allensworth-James, Gwen V. Childs, Tiffany K. Miles, Anessa Haney, Angus M. MacNicol, Ana Rita Silva Moreira, Angela K. Odle
Publikováno v:
J Endocrinol
Anterior pituitary somatotropes are important metabolic sensors responding to leptin by secreting growth hormone (GH). However, reduced leptin signals caused by fasting have not always correlated with reduced serum GH. Reports show that fasting may s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d3951cecaee13d70fac5bcc87845af
https://doi.org/10.1530/joe-20-0275
https://doi.org/10.1530/joe-20-0275
Autor:
Jewel Banik, Gwen V Childs, Linda L Hardy, Juchan Lim, Angus M MacNicol, Melanie C MacNicol, Sophia Tomlinson, Alicja Urbaniak
Publikováno v:
Journal of the Endocrine Society. 6:A578-A578
The pituitary gland controls responses to changing physiological requirements during growth, pregnancy, puberty, and stress. Synthesis and secretion of appropriate pituitary hormones in response to changing organismal demands is mediated through a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa28424451c925b5d929a0680d102971
https://doi.org/10.1210/jendso/bvac150.1199
https://doi.org/10.1210/jendso/bvac150.1199
Autor:
Timothy C. Chambers, Adam Huczyński, Angus M. MacNicol, Alicja Urbaniak, Anika Moorjani, Melanie C. MacNicol, Robert L. Eoff, Daniel Fil, Michał Sulik, Michalina Kupsik, Michał Antoszczak, Megan R. Reed, Sarah Heflin
Publikováno v:
Biomed Pharmacother
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111815-(2021)
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111815-(2021)
Breast cancer remains one of the leading cancers among women. Cancer stem cells (CSCs) are tumor-initiating cells which drive progression, metastasis, and reoccurrence of the disease. CSCs are resistant to conventional chemo- and radio-therapies and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef21ed5bfec6bfee76c9cf62226cd89
https://europepmc.org/articles/PMC8429223/
https://europepmc.org/articles/PMC8429223/
