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pro vyhledávání: '"Melanie Bomier"'
Autor:
Donald W. Kundel, Olga Zhdankin, Ronald R. Regal, Melanie Bomier, Teresa A. Rose-Hellekant, Mingqian Duan, Evan Odean
Publikováno v:
Cancer Prevention Research. 8:A15-A15
ELF5 is a master regulator of breast lobular development, is enriched in luminal progenitor cells and has been implicated in breast carcinogenesis and may be a chemopreventive biomarker and target. In our laboratory, mammary cancer prone mice treated
Publikováno v:
Cancer Prevention Research. 6:A03-A03
The cells within the mammary gland that are altered by tamoxifen chemoprevention and correlate with abrogation of tumorigenesis are unknown. We have documented that a 60 day tamoxifen chemopreventive regimen reduces tumor incidence in NRL-TGFalpha an
Publikováno v:
Molecular Cancer Research. 11:B004-B004
Our goal was to define the balance of normal, healthy mammary epithelial cell subpopulations, including putative stem, progenitor and mature cells, in mouse models of luminal breast cancer prior to tumor development. We isolated mammary cells using f