Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Melanie B White"'
Autor:
Jasmohan S Bajaj, Sili Fan, Leroy R Thacker, Andrew Fagan, Edith Gavis, Melanie B White, Douglas M Heuman, Michael Fuchs, Oliver Fiehn
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0223061 (2019)
BackgroundCirrhosis can alter several metabolic pathways. Metabolomics could prognosticate outcomes like hepatic encephalopathy (HE), transplant, hospitalization and death.AimDetermine changes in serum and urine metabolomics in cirrhotics who develop
Externí odkaz:
https://doaj.org/article/9cc9f4bc7ba146d28bff0c015688790d
Autor:
Jasmohan S Bajaj, Douglas M Heuman, Arun J Sanyal, Phillip B Hylemon, Richard K Sterling, R Todd Stravitz, Michael Fuchs, Jason M Ridlon, Kalyani Daita, Pamela Monteith, Nicole A Noble, Melanie B White, Andmorgan Fisher, Masoumeh Sikaroodi, Huzefa Rangwala, Patrick M Gillevet
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60042 (2013)
Hepatic encephalopathy (HE) represents a dysfunctional gut-liver-brain axis in cirrhosis which can negatively impact outcomes. This altered gut-brain relationship has been treated using gut-selective antibiotics such as rifaximin, that improve cognit
Externí odkaz:
https://doaj.org/article/45dc96f92b3e4866b15094e7e2c6d7f9
Autor:
Jawaid Shaw, Chathur Acharya, Somaya Albhaisi, Andrew Fagan, Sara McGeorge, Melanie B. White, Jatinder Lachar, Jessica Olson, Amy Olofson, Lori Bergstrom, Patrick S. Kamath, Jasmohan S. Bajaj
Publikováno v:
Hepatology Communications, Vol 7, Iss 2, Pp e0030-e0030 (2023)
Background:. App-based technologies could enhance patient and caregiver communication and provide alerts that potentially reducing readmissions. However, the burden of App alerts needs to be optimized to reduce provider burnout. Aim:. The purpose of
Externí odkaz:
https://doaj.org/article/4e72bc1c553d4026adb884ceacb441a5
Autor:
Douglas M. Heuman, Patrick M. Gillevet, Andrew Fagan, Melanie B. White, Edith Gavis, Ravishankar K. Iyer, Krishnakant Saboo, Mihir V. Iyer, Jasmohan S. Bajaj, Michael Fuchs, Masoumeh Sikaroodi, Amirhossein Shamsaddini, Chang Hu
Publikováno v:
J Hepatol
Background & Aims Altered microbiota can affect the gut-liver-brain axis in cirrhosis and hepatic encephalopathy (HE), but the impact of sex on these changes is unclear. We aimed to determine differences in fecal microbiota composition/functionality
Autor:
Felicia Tinsley, Melanie B. White, Leroy R. Thacker, James B. Wade, Jasmohan S. Bajaj, Velimir A. Luketic, Hannah Lee, Douglas M. Heuman, Chathur Acharya, Puneet Puri, Arun J. Sanyal, Andrew Fagan, Scott Matherly, Mohammad S. Siddiqui, Michael Fuchs, R. Todd Stravitz, Richard K. Sterling, HoChong Gilles
Publikováno v:
Dig Dis Sci
BACKGROUND: Cirrhosis is associated with poor health related quality of life (HRQOL), cognitive dysfunction (CD) and lack of coordination leading to falls. Tandem gait (TG;heel-toe) can be used to assess coordination. The impact and relationship betw
Autor:
Masoumeh Sikaroodi, Michael Fuchs, Aldo Torre, Ivvone Escalona Nandez, Edith Gavis, Jasmohan S. Bajaj, Andrew Fagan, Patrick M. Gillevet, Omar De Leon Osorio, Mayra Lara Rojas, Melanie B. White
Publikováno v:
Liver International. 40:1395-1407
Background & aims Gut microbiota are affected by diet and ethnicity, which impacts cognition and hospitalizations in cirrhosis. Aim Study interactions of diet with microbiota and impact on hospitalizations and cognition in American and Mexican cohort
Autor:
Randolph de la Rosa Rodriguez, Patrick M. Gillevet, Puneeta Tandon, Hugo E. Vargas, Patrick S. Kamath, Andrew Fagan, K. Rajender Reddy, Ram Subramanian, Tejasav S. Sehrawat, Melanie B. White, Leroy R. Thacker, Edith Gavis, Paul J. Thuluvath, G. Garcia-Tsao, Jasmohan S. Bajaj, Jennifer C. Lai, Masoumeh Sikaroodi, Jacqueline G. O'Leary, Florence Wong
Publikováno v:
Gastroenterology
Gastroenterology, vol 159, iss 5
Gastroenterology, vol 159, iss 5
Background & Aims Inpatients with cirrhosis have high rates of acute-on-chronic failure (ACLF) development and high mortality within 30 days of admission to the hospital. Better biomarkers are needed to predict these outcomes. We performed metabolomi
Autor:
Jagpal Singh Klair, Kavish R. Patidar, James B. Wade, Christopher Flud, Leroy R. Thacker, Edith Gavis, Douglas M. Heuman, Melanie B. White, Sanath Allampati, Andres Duarte-Rojo, Jasmohan S. Bajaj
Publikováno v:
Metabolic Brain Disease. 34:289-295
BACKGROUND & AIMS: Covert hepatic encephalopathy (CHE) affects cognition in a multidimensional fashion. Current guidelines recommend performing Psychometric Hepatic Encephalopathy Score (PHES) and a second test to diagnose CHE for multi-center trials
Autor:
Xiaojiaoyang Li, Runping Liu, H. Robert Lippman, Phillip B. Hylemon, Siddhartha S. Ghosh, James B. Wade, Jason D. Kang, Derrick Zhao, Emily C. Gurley, Yunzhou Li, Huiping Zhou, Melanie B. White, Jasmohan S. Bajaj, Vishwadeep Ahluwalia, Andrew Fagan
Publikováno v:
Hepatology Communications
Patients with cirrhosis are growing older, which could have an impact on brain dysfunction beyond hepatic encephalopathy. Our aim was to study the effect of concomitant aging and cirrhosis on brain inflammation and degeneration using human and animal
Autor:
Rengul Cetin Atalay, Douglas M. Heuman, Dilara Turan, Masoumeh Sikaroodi, Melanie B. White, Leila Mabudian, Robert E. Brown, Phillip B. Hylemon, Patrick M. Gillevet, Andrew Fagan, Chathur Acharya, Ramazan Idilman, Jasmohan S. Bajaj, Jessica Wang, Leroy R. Thacker, Edith Gavis, Matthew Hood, Fatih Karakaya
Publikováno v:
Hepatology. 68:234-247
The relative ranking of cirrhosis-related deaths differs between high-/middle-income countries. Gut microbiome is affected in cirrhosis and is related to diet. Our aim was to determine the effect of differing dietary habits on gut microbiota and clin