Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Melanie A. Ruffner"'
Publikováno v:
Allergology International, Vol 73, Iss 2, Pp 188-195 (2024)
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE mediated food allergy presenting with delayed onset of projectile vomiting in the absence of cutaneous and respiratory symptoms. The pathophysiology of FPIES remains poorly characterize
Externí odkaz:
https://doaj.org/article/eb9747fc4d4d4630866795c24a698cfb
Autor:
Masaru Sasaki, Takeo Hara, Joshua X. Wang, Yusen Zhou, Kanak V. Kennedy, Chizoba N. Umeweni, Maiya A. Alston, Zachary C. Spergel, Satoshi Ishikawa, Ryugo Teranishi, Ritsu Nakagawa, Emily A. Mcmillan, Kelly A. Whelan, Tatiana A. Karakasheva, Kathryn E. Hamilton, Melanie A. Ruffner, Amanda B. Muir
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 923-937 (2024)
Background & Aims: Epithelial disruption in eosinophilic esophagitis (EoE) encompasses both impaired differentiation and diminished barrier integrity. We have shown that lysyl oxidase (LOX), a collagen cross-linking enzyme, is up-regulated in the eso
Externí odkaz:
https://doaj.org/article/4642d52f7d81435797854e2d8c616673
Autor:
Takeo Hara, Yuta Kasagi, Joshua Wang, Masaru Sasaki, Bailey Aaron, Adam Karami, Masataka Shimonosono, Rieko Shimonosono, Hisatsugu Maekawa, Lauren Dolinsky, Benjamin Wilkins, Jeremy Klein, Jane Wei, Kathryn Nunes, Kristle Lynch, Jonathan M. Spergel, Kathryn E. Hamilton, Melanie A. Ruffner, Tatiana A. Karakasheva, Kelly A. Whelan, Hiroshi Nakagawa, Amanda B. Muir
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1449-1467 (2022)
Background & Aims: Although basal cell hyperplasia is a histologic hallmark of eosinophilic esophagitis (EoE), little is known about the capabilities of epithelial renewal and differentiation in the EoE inflammatory milieu. In murine esophageal epith
Externí odkaz:
https://doaj.org/article/6cf51597b7804a5da4a9fd173aba4b20
Autor:
Paulina Tran, Laura Gober, Elizabeth K. Garabedian, Ramsay L. Fuleihan, Jennifer M. Puck, Kathleen E. Sullivan, Jonathan M. Spergel, Melanie A. Ruffner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
RationaleEosinophilic gastrointestinal disorders (EGID), including eosinophilic esophagitis (EoE), are inflammatory disorders of the gastrointestinal mucosa mediated by complex immune mechanisms. Although there have been initial reports of EGID in pa
Externí odkaz:
https://doaj.org/article/8d040440ecdd488682ba0dce651efc75
Autor:
Sara Anvari, Melanie A. Ruffner
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE, cell-mediated food allergy, commonly diagnosed in infants and young children. In recent years, new-onset adult FPIES has been recognized. The underlying pathogenic mechanism of FPIES h
Externí odkaz:
https://doaj.org/article/e0ceb518626b4f6383f2eba61ebf2ae1
Autor:
Bridget Godwin, Chris Liacouras, Vijay Mehta, Joshua Eisenberg, Atu Agawu, Terri Brown-Whitehorn, Melanie A. Ruffner, Ritu Verma, Antonella Cianferoni, Jonathan M. Spergel, Amanda B. Muir
Publikováno v:
Frontiers in Pediatrics, Vol 6 (2018)
Background: Eosinophilic esophagitis is a chronic, immune-mediated disease characterized by symptoms of esophageal dysfunction and ≥15 eosinophils/high-powered field (eos/hpf). Proton pump inhibitor responsive esophageal eosinophilia (1) is an enti
Externí odkaz:
https://doaj.org/article/eef08093079248beaea051c1dcb7dd20
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Viral infections are commonplace and often innocuous. Nevertheless, within the population of patients with primary immunodeficiencies (PIDDs), viral infections can be the feature that drives a diagnostic evaluation or can be the most significant morb
Externí odkaz:
https://doaj.org/article/d8f2ab32394240169ad249dbada44798
Autor:
Lacey B, Robinson, Melanie A, Ruffner
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 10:3117-3123
Proton pump inhibitors (PPIs) are widely prescribed and are indicated for the treatment of several gastrointestinal disorders. Allergists may prescribe PPIs as a result of the coincidence of gastroesophageal reflux disease with asthma or rhinitis, or
Publikováno v:
American Journal of Gastroenterology. 117:1519-1522
Autor:
Benjamin L. Wright, Justin T. Schwartz, Melanie A. Ruffner, Glenn T. Furuta, Nirmala Gonsalves, Evan S. Dellon, Seema S. Aceves
Publikováno v:
The Journal of allergy and clinical immunology. 150(2)