Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Melanie A. Meier"'
Autor:
Andreas Konopa, Melanie A. Meier, Miriam J. Franz, Emanuele Bernardinelli, Anna-Lena Voegele, Raja Atreya, Silvia Ribback, Stephanie Roessler, Achim Aigner, Kerstin Singer, Stephan Singer, Antonio Sarikas, Susanne Muehlich
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF), which controls fundamental biological processes such as cell growth, migration, and differentiation. MRTF and SRF transcriptional activi
Externí odkaz:
https://doaj.org/article/470cbd2eb6b54616968344e265c1703a
Autor:
Laura Schreyer, Constanze Mittermeier, Miriam J. Franz, Melanie A. Meier, Dietmar E. Martin, Kerstin C. Maier, Kerstin Huebner, Regine Schneider-Stock, Stephan Singer, Kerstin Holzer, Dagmar Fischer, Silvia Ribback, Bernhard Liebl, Thomas Gudermann, Achim Aigner, Susanne Muehlich
Publikováno v:
Cancers, Vol 13, Iss 21, p 5373 (2021)
Human hepatocellular carcinoma (HCC) is among the most lethal and common cancers in the human population, and new molecular targets for therapeutic intervention are urgently needed. Deleted in liver cancer 1 (DLC1) was originally identified as a tumo
Externí odkaz:
https://doaj.org/article/9a46f0305c3f4da6928cc0db1f054c25
Autor:
Andrea Romagnani, Valentina Vettore, Tanja Rezzonico-Jost, Sarah Hampe, Elsa Rottoli, Wiebke Nadolni, Michela Perotti, Melanie A. Meier, Constanze Hermanns, Sheila Geiger, Gunther Wennemuth, Camilla Recordati, Masayuki Matsushita, Susanne Muehlich, Michele Proietti, Vladimir Chubanov, Thomas Gudermann, Fabio Grassi, Susanna Zierler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Gut-homing and colonization of T cells are important for maintaining local immune homoeostasis and protective immunity. Here the authors show that the kinase activity of TRPM7 regulates Th17 differentiation and T cell alloreactivity in the gut by mod
Externí odkaz:
https://doaj.org/article/81c11da70637480eb4d002bc8644c76b
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2
Autor:
Kerstin Huebner, Katharina Erlenbach-Wuensch, Jan Prochazka, Ilir Sheraj, Chuanpit Hampel, Blanka Mrazkova, Tereza Michalcikova, Jolana Tureckova, Veronika Iatsiuk, Anne Weissmann, Fulvia Ferrazzi, Philipp Kunze, Enise Nalli, Elisabeth Sammer, Annemarie Gehring, Marie M. Cheema, Markus Eckstein, Eva-Maria Paap, Agnes Soederberg, Corinna Fischer, Sushmita Paul, Vijayalakshmi Mahadevan, Benardina Ndreshkjana, Melanie A. Meier, Susanne Muehlich, Carol I. Geppert, Susanne Merkel, Robert Grutzmann, Adriana Roehe, Sreeparna Banerjee, Arndt Hartmann, Radislav Sedlacek, Regine Schneider-Stock
Publikováno v:
Cellular and Molecular Life Sciences. 79
In cancer, the activating transcription factor 2 (ATF2) has pleiotropic functions in cellular responses to growth stimuli, damage, or inflammation. Due to only limited studies, the significance of ATF2 in colorectal cancer (CRC) is not well understoo
Autor:
Dena Esfandyari, Bio Maria Ghéo Idrissou, Konstantin Hennis, Petros Avramopoulos, Anne Dueck, Ibrahim El-Battrawy, Laurenz Grüter, Melanie Annemarie Meier, Anna Christina Näger, Deepak Ramanujam, Tatjana Dorn, Thomas Meitinger, Christian Hagl, Hendrik Milting, Martin Borggrefe, Stefanie Fenske, Martin Biel, Andreas Dendorfer, Yassine Sassi, Alessandra Moretti, Stefan Engelhardt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Nature Communications
Nature Communications
Abnormalities of ventricular action potential cause malignant cardiac arrhythmias and sudden cardiac death. Here, we aim to identify microRNAs that regulate the human cardiac action potential and ask whether their manipulation allows for therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8e8e06b9af205133c816f17afbfafa
https://hdl.handle.net/10919/107641
https://hdl.handle.net/10919/107641
Autor:
Dietmar E. Martin, Bernhard Liebl, Susanne Muehlich, Kerstin C. Maier, Miriam J. Franz, Regine Schneider-Stock, Dagmar Fischer, Constanze Mittermeier, Laura Schreyer, Melanie A. Meier, Kerstin Huebner, Stephan Singer, Silvia Ribback, Thomas Gudermann, Kerstin Holzer, Achim Aigner
Publikováno v:
Cancers, Vol 13, Iss 5373, p 5373 (2021)
Cancers
Volume 13
Issue 21
Cancers
Volume 13
Issue 21
Simple Summary Hepatocellular carcinoma (HCC) ranks second among the leading causes of cancer-related death. Since current therapeutic options are very limited, a deeper understanding of the molecular mechanisms underlying the tumor onset and progres
Autor:
D Jira, Anja Pickhard, Markus Wirth, Rudolf Reiter, Guido Piontek, Melanie Annemarie Meier, Jürgen Schlegel, Johannes Doescher
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 122:491-499
Objective In squamous cell carcinoma of the pharynx and larynx, NOTCH1 downstream signaling has been shown to be activated. The NOTCH1 signaling pathway has not been examined in detail for sinonasal squamous cell carcinomas (SNSCCs). The aim of this
Autor:
Gunther Wennemuth, Susanna Zierler, Wiebke Nadolni, Constanze Hermanns, Masayuki Matsushita, Valentina Vettore, Susanne Muehlich, Elsa Rottoli, Michele Proietti, Camilla Recordati, Michela Perotti, Thomas Gudermann, Fabio Grassi, Vladimir Chubanov, Sarah Hampe, Tanja Rezzonico-Jost, Melanie A Meier, Andrea Romagnani, Sheila Geiger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
The melastatin-like transient-receptor-potential-7 protein (TRPM7), harbouring a cation channel and a serine/threonine kinase, has been implicated in thymopoiesis and cytokine expression. Here we show, by analysing TRPM7 kinase-dead mutant (Trpm7 R/R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12c7d2a0fa9281bc07a9f0d5a60e3f6
http://doc.rero.ch/record/327179/files/Romagnani_NC_2017.pdf
http://doc.rero.ch/record/327179/files/Romagnani_NC_2017.pdf
Autor:
Laura Schreyer, Susanne Muehlich, Wiebke Nadolni, Vladimir Chubanov, Kerstin Holzer, Silvia Ferioli, Stephan Singer, Susanna Zierler, Bernhard Liebl, Constanze Mittermeier, Katharina Woerther, Sandra Voringer, Thomas Gudermann, Melanie A Meier
Publikováno v:
Oncogene. 39(11)
Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF) that mediates the expression of genes involved in cell proliferation, migration and differentiation. There is mounting evidence that MRTFs and SRF
In the recent years, the role of actin and actin-binding proteins in gene transcription has received considerable attention. Nuclear monomeric and polymerized actin and several actin binding proteins have been detected in the mammalian cell nucleus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a437b92e2b0309e6112dd9dd3993b75f
https://europepmc.org/articles/PMC4916864/
https://europepmc.org/articles/PMC4916864/