Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Melanie A. Higgins"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 589-596 (2024)
Hygromycin A is a broad-spectrum antibiotic that contains a furanose, cinnamic acid, and aminocyclitol moieties. The biosynthesis of the aminocyclitol has been proposed to proceed through six enzymatic steps from glucose 6-phosphate through myo-inosi
Externí odkaz:
https://doaj.org/article/590bd35339bf4386b25276aa5c80f4ea
Autor:
Polina Beskrovnaya, Ryan A. Melnyk, Zhexian Liu, Yang Liu, Melanie A. Higgins, Yi Song, Katherine S. Ryan, Cara H. Haney
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/fadb745cdeac4bdab1db951bcc2e87c2
Autor:
Polina Beskrovnaya, Ryan A. Melnyk, Zhexian Liu, Yang Liu, Melanie A. Higgins, Yi Song, Katherine S. Ryan, Cara H. Haney
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Plant root-associated microbes promote plant growth and elicit induced systemic resistance (ISR) to foliar pathogens. In an attempt to find novel growth-promoting and ISR-inducing strains, we previously identified strains of root-associated
Externí odkaz:
https://doaj.org/article/ce2d410e3d984061a0b959e71895d258
Autor:
Christopher J. Day, Adrienne W. Paton, Melanie A. Higgins, Lucy K. Shewell, Freda E.-C. Jen, Benjamin L. Schulz, Brock P. Herdman, James C. Paton, Michael P. Jennings
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Subtilase cytotoxin (SubAB) of Escherichia coli is an AB5 class bacterial toxin. The pentameric B subunit (SubB) binds the cellular carbohydrate receptor, α2–3-linked N-glycolylneuraminic acid (Neu5Gc). Neu5Gc is not expressed on normal h
Externí odkaz:
https://doaj.org/article/044bf5c3974f4b87808e48ec6742c49f
Autor:
Layla K. Mahdi, Melanie A. Higgins, Christopher J. Day, Joe Tiralongo, Lauren E. Hartley-Tassell, Michael P. Jennings, David L. Gordon, Adrienne W. Paton, James C. Paton, Abiodun D. Ogunniyi
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 236-243 (2017)
Streptococcus pneumoniae (the pneumococcus) is a major human pathogen, causing a broad spectrum of diseases including otitis media, pneumonia, bacteraemia and meningitis. Here we examined the role of a potential pneumococcal meningitis vaccine antige
Externí odkaz:
https://doaj.org/article/b5126e969e014b9ea74639c810eb52c7
Autor:
Gregory Arnal, Stephen G. Withers, Melanie A. Higgins, Spencer S. Macdonald, Harry Brumer, Katherine S. Ryan, Gregor Tegl
Publikováno v:
ACS Chemical Biology. 16:701-711
N-Glycosylation is a fundamental protein modification found in both eukaryotes and archaea. Despite lacking N-glycans, many commensal and pathogenic bacteria have developed mechanisms to degrade these isoforms for a variety of functions, including nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939d2a2504b499fe4939b8fcab93eae5
https://doi.org/10.1021/acschembio.0c00995
https://doi.org/10.1021/acschembio.0c00995
Publikováno v:
Nature Chemical Biology. 15:1043-1048
Microbes produce specialized metabolites to thrive in their natural habitats. However, it is rare that a given specialized metabolite is biosynthesized via pathways with distinct intermediates and enzymes. Here, we show that the core assembly mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6afd33510e2c489682040806c3275148
https://doi.org/10.1038/s41589-019-0331-5
https://doi.org/10.1038/s41589-019-0331-5
Publikováno v:
Journal of the American Chemical Society. 141:12258-12267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::048d7c84452840653024922e10f66f67
https://doi.org/10.1021/jacs.9b03307
https://doi.org/10.1021/jacs.9b03307
Autor:
Melanie A. Higgins, Polina Beskrovnaya, Yi Song, Cara H. Haney, Katherine S. Ryan, Zhexian Liu, Ryan A. Melnyk, Yang Liu
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
Microbiome-associated bacteria can have diverse effects on health of their hosts, yet the genetic and molecular bases of these effects have largely remained elusive. This work demonstrates that a novel bacterial locus can modulate systemic plant immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ec6e984d6cb40ca4e51f4737ad1aaf
https://journals.asm.org/doi/10.1128/mBio.01906-20
https://journals.asm.org/doi/10.1128/mBio.01906-20
Autor:
Katherine S. Ryan, Melanie A. Higgins, Yang Liu, Yi Song, Zhexian Liu, Cara H. Haney, Polina Beskrovnaya, Ryan A. Melnyk
Publikováno v:
mBio, Vol 11, Iss 3, p e00575-20 (2020)
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3 (2020)
Plant root-associated microbes promote plant growth and induce systemic resistance (ISR) to foliar pathogens. In an attempt to find novel growth-promoting and ISR-inducing strains, we previously identified strains of root-associated Pseudomonas spp.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c067aab7cb660f146ac98d22852c930
