Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Melanie, Meyer"'
Autor:
Iris Früholz, Melanie Meyer-Luehmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Microglia, the resident immune cells of the central nervous system, play a crucial role in regulating adult neurogenesis and contribute significantly to the pathogenesis of Alzheimer’s disease (AD). Under physiological conditions, microglia support
Externí odkaz:
https://doaj.org/article/0c3507cdadb54ad2b5e888ded5353849
Autor:
Subash C. Malik, Jia-Di Lin, Stephanie Ziegler-Waldkirch, Stefan Tholen, Sachin S. Deshpande, Marius Schwabenland, Oliver Schilling, Andreas Vlachos, Melanie Meyer-Luehmann, Christian Schachtrup
Publikováno v:
Cells, Vol 12, Iss 23, p 2757 (2023)
Nuclear pore complexes (NPCs) are highly dynamic macromolecular protein structures that facilitate molecular exchange across the nuclear envelope. Aberrant NPC functioning has been implicated in neurodegeneration. The translocated promoter region (Tp
Externí odkaz:
https://doaj.org/article/3e5461d4500d4580a304040de803716d
Autor:
Ilona Trautmannsberger, Laura Kolberg, Melanie Meyer-Buehn, Johannes Huebner, Guido Werner, Robert Weber, Valerie Heselich, Sebastian Schroepf, Hans-Georg Muench, Ulrich von Both
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Vancomycin-resistant Enterococcus faecium (VREfm) strains are one of the most important pathogens causing nosocomial infections in Germany. Due to limited treatment options and an increased risk for acquisition in immunocompromise
Externí odkaz:
https://doaj.org/article/3bda8e87d28b49808ac13ee60fd938ad
Autor:
Michael Marner, Laura Kolberg, Julia Horst, Nils Böhringer, Johannes Hübner, I Dewa M. Kresna, Yang Liu, Ute Mettal, Lei Wang, Melanie Meyer-Bühn, Sanja Mihajlovic, Matthias Kappler, Till F. Schäberle, Ulrich von Both
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The emergence and spread of antimicrobial resistance (AMR) in Gram-negative pathogens, such as carbapenem-resistant Pseudomonas aeruginosa, pose an increasing threat to health care. Patients with immunodeficiencies or chronic pulmonary disea
Externí odkaz:
https://doaj.org/article/33dc2de94e8a4e6fb2ddc2de32f8329d
Autor:
Vanessa Aires, Stephanie Ziegler-Waldkirch, Marina Friesen, Wilfried Reichardt, Daniel Erny, Desiree Loreth, Andrew Harborne, Oliver Kretz, Dominik von Elverfeldt, Melanie Meyer-Luehmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Neuropathologically, Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-beta peptide (Aβ) and subsequent formation of the so-called Aβ plaques. Along with neuronal loss, previous studies report white matter anomalies and cor
Externí odkaz:
https://doaj.org/article/c42ba31c61ab4449a1841d3a67b03bb8
Autor:
Charlotte Mezö, Nikolaos Dokalis, Omar Mossad, Ori Staszewski, Jana Neuber, Bahtiyar Yilmaz, Daniel Schnepf, Mercedes Gomez de Agüero, Stephanie C. Ganal-Vonarburg, Andrew J. Macpherson, Melanie Meyer-Luehmann, Peter Staeheli, Thomas Blank, Marco Prinz, Daniel Erny
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract It was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions or treatments with antibioti
Externí odkaz:
https://doaj.org/article/1ef4ef2c7b524187aa55817e1899a3d0
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Prompt initiation of empiric therapy is common practice in case of suspected meningitis or encephalitis. However, in children the most common pathogens are viruses that usually do not require and are not covered by the applied ant
Externí odkaz:
https://doaj.org/article/437c9da8adaf44dfb473174e27b14c6a
Autor:
Alexander Joachim, Felix Dewald, Isabelle Suárez, Michael Zemlin, Isabelle Lang, Regine Stutz, Anna Marthaler, Hans Martin Bosse, Nadine Lübke, Juliane Münch, Marie-Annett Bernard, Kathrin Jeltsch, Burkhard Tönshoff, Niklas Weidner, Hans-Georg Kräusslich, Lena Birzele, Johannes Hübner, Patricia Schmied, Melanie Meyer-Bühn, Gibran Horemheb-Rubio, Oliver A. Cornely, Heinz Haverkamp, Gerhard Wiesmüller, Gerd Fätkenheuer, Barbara Hero, Rolf Kaiser, Jörg Dötsch, Jan Rybniker, Zülfü C. Cosgun, Christoph Hünseler, Jana Schönenkorb, Juliane Wurm, Florian Klein, Eva Heger, Elena Knops, Saleta Sierra-Aragón, Alina Chloé Kretschmer, Rosanne Sprute, Annelene Kossow, Martin Hellmich, Kija Shah-Hosseini, Michael Weiss, Sybelle Goedicke-Fritz, Elisabeth Kaiser, Sascha Meyer, Nastasja Seiwert, Sigrun Smola, Thorsten Pfuhl, Stefan Lohse, Anna-Kathrin Schupp, Jörg Timm, Nehle Gröne, Hellen Lesmann, Renate Bredahl, Lukas Schneble, Martin Turinsky, Christian Patry, Georg F Hoffmann, Barbara Müller, Kathleen Börner, Paul Schnitzler, Anke-Mareil Heuser, Andreas Welker, Ulrich von Both, Anna Kern
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101082- (2021)
Background: The extent to which children and adolescents contribute to SARS-CoV-2 transmission remains not fully understood. Novel high-capacity testing methods may provide real-time epidemiological data in educational settings helping to establish a
Externí odkaz:
https://doaj.org/article/0637ea85d3d9416fa8369cfffe01ec5c
Publikováno v:
Infection. 51:583-588
Purpose Resistance of Staphylococcus aureus to vancomycin includes a general increase of minimal inhibitory concentrations (MIC) within the susceptible range over time (Vancomycin MIC Creep) and the presence of a subset of the bacterial population th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee06779cf6917d011c9df62d8207fd46
https://doi.org/10.1007/s15010-023-02036-5
https://doi.org/10.1007/s15010-023-02036-5
Autor:
Simone Brioschi, Paolo d’Errico, Lukas S. Amann, Hana Janova, Sonja M. Wojcik, Melanie Meyer-Luehmann, Lawrence Rajendran, Peter Wieghofer, Rosa C. Paolicelli, Knut Biber
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
A growing body of evidence indicates that microglia actively remove synapses in vivo, thereby playing a key role in synaptic refinement and modulation of brain connectivity. This phenomenon was mainly investigated in immunofluorescence staining and c
Externí odkaz:
https://doaj.org/article/4212dc9e7c4743df81cd46c466e44482