Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Melanie, Leggate"'
Publikováno v:
Experimental Physiology. 106:1460-1469
New findings What is the central question of this study? Does exercise affect vitamin D receptor expression in T lymphocytes in young, middle-aged and older adults? What is the main finding and its importance? Moderate-intensity cycling exercise incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55207c178615a4db9c855eb302a7b487
https://doi.org/10.1113/ep089480
https://doi.org/10.1113/ep089480
Autor:
Hannah M, Lithgow, Melanie, Leggate
Publikováno v:
International Journal of Exercise Science
Our aim was to investigate the acute effects of a single bout of high intensity intermittent training (HIIT) on glucose tolerance and other physiological and metabolic markers in non-diabetic older adults. Fourteen healthy older adults (age, 64 ± 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47de28d0006d6a4eddafa3cd44b0174a
https://pubmed.ncbi.nlm.nih.gov/29795727
https://pubmed.ncbi.nlm.nih.gov/29795727
Publikováno v:
Sims, A, Leggate, M & Campbell, A 2019, ' Exercise Window Trial in Newly Diagnosed Breast Cancer-Letter ', Clinical Cancer Research . https://doi.org/10.1158/1078-0432.CCR-19-2571
We read with great interest the article by Ligibel and colleagues ([1][1]), of the Pre-Operative Health and Body (PreHAB) study looking at the molecular effects of exercise on breast tumors between diagnosis and surgery. The reported upregulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee76215426fa389258368e17d508b027
https://doi.org/10.1158/1078-0432.ccr-19-2571
https://doi.org/10.1158/1078-0432.ccr-19-2571
Autor:
Gerry P McCann, Laura J. Gray, Pierre Croisille, Emma G. Wilmot, Kamlesh Khunti, Danielle H. Bodicoat, Melanie J. Davies, Thomas Yates, Trish Gorely, Patrick Clarysse, Anvesha Singh, Melanie Leggate, Jamal N Khan, Joost P.A. Kuijer, Myra A. Nimmo
Publikováno v:
Diabetic Medicine
Diabetic Medicine, Wiley, 2014, 31 (7), pp.794-798. 〈10.1111/dme.12431〉
Wilmot, E G, Leggate, M, Khan, J N, Yates, T, Gorely, T, Bodicoat, D H, Khunti, K, Kuijer, J P A, Gray, L J, Singh, A, Clarysse, P, Croisille, P, Nimmo, M A, McCann, G P & Davies, M J 2014, ' Type 2 diabetes mellitus and obesity in young adults: the extreme phenotype with early cardiovascular dysfunction ', Diabetic Medicine, vol. 31, no. 7, pp. 794-798 . https://doi.org/10.1111/dme.12431
Diabetic Medicine, 31(7), 794-798. Wiley-Blackwell
Diabetic Medicine, Wiley, 2014, 31 (7), pp.794-798. ⟨10.1111/dme.12431⟩
Diabetic Medicine, Wiley, 2014, 31 (7), pp.794-798. 〈10.1111/dme.12431〉
Wilmot, E G, Leggate, M, Khan, J N, Yates, T, Gorely, T, Bodicoat, D H, Khunti, K, Kuijer, J P A, Gray, L J, Singh, A, Clarysse, P, Croisille, P, Nimmo, M A, McCann, G P & Davies, M J 2014, ' Type 2 diabetes mellitus and obesity in young adults: the extreme phenotype with early cardiovascular dysfunction ', Diabetic Medicine, vol. 31, no. 7, pp. 794-798 . https://doi.org/10.1111/dme.12431
Diabetic Medicine, 31(7), 794-798. Wiley-Blackwell
Diabetic Medicine, Wiley, 2014, 31 (7), pp.794-798. ⟨10.1111/dme.12431⟩
Aim A pilot study to phenotype young adults ( 0.05). Peak early diastolic strain rate was reduced in the group with Type 2 diabetes [1.51 (0.24)/s] compared with the lean control [1.97 (0.34)/s, P = 0.001] and obese control [1.78 (0.39)/s, P = 0.042]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c46eca320d31419c76eebbccc0c94d
https://doi.org/10.1111/dme.12431
https://doi.org/10.1111/dme.12431
Autor:
Rebecca A. Vennard, Wayne G. Carter, Sarah Sribala-Sundaram, Matthew J. Evans, Melanie Leggate, Myra A. Nimmo
Publikováno v:
Journal of Applied Physiology
This study aimed to determine whether 2 wk of high-intensity intermittent training (HIIT) altered inflammatory status in plasma and adipose tissue in overweight and obese males. Twelve participants [mean (SD): age 23.7 (5.2) yr, body mass 91.0 (8.0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa32f05750ddbcb1d0f0abba0e26a54
http://europepmc.org/articles/PMC3331586
http://europepmc.org/articles/PMC3331586
Publikováno v:
Cell Stress and Chaperones. 15:827-833
As interleukin-6 (IL-6), its soluble receptor (sIL-6R), and the IL-6/sIL-6R complex is transiently elevated in response to prolonged moderate-intensity exercise, this study investigated how these levels would be modulated by an acute bout of high-int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65400df96f1c5f338cd4cba735a7345
https://doi.org/10.1007/s12192-010-0192-z
https://doi.org/10.1007/s12192-010-0192-z
Publikováno v:
Metabolism
Fat loss in response to exercise training varies between individuals, even when differences in compliance to the exercise program are accounted for. The purpose of this study was to investigate whether individual variation in change in fasting respir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5e5a9d971ce2820e2843028326203e
https://doi.org/10.1016/j.metabol.2009.04.016
https://doi.org/10.1016/j.metabol.2009.04.016
Autor:
Emma G. Wilmot, Kamlesh Khunti, Patrick Clarysse, Anvesha Singh, Mark A. Horsfield, Thomas Yates, Melanie Leggate, Gerry P McCann, Melanie J. Davies, Myra A. Nimmo, John Biglands, Pierre Croisille, Jamal N Khan
Publikováno v:
European Heart Journal-Cardiovascular Imaging
European Heart Journal-Cardiovascular Imaging, Oxford UP, 2014, 15 (11), pp.1263--1269
European Heart Journal-Cardiovascular Imaging, Oxford UP, 2014, 15 (11), pp.1263-1269. ⟨10.1093/ehjci/jeu121⟩
European Heart Journal-Cardiovascular Imaging, Oxford UP, 2014, 15 (11), pp.1263--1269
European Heart Journal-Cardiovascular Imaging, Oxford UP, 2014, 15 (11), pp.1263-1269. ⟨10.1093/ehjci/jeu121⟩
Aims To assess the cardiac, vascular, anthropometric, and biochemical determinants of subclinical diastolic dysfunction in younger adults with Type 2 diabetes mellitus (T2DM) using multiparametric contrast-enhanced cardiovascular magnetic resonance (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d04df9c43c48fb4c8928a7daf937cef
https://hal.archives-ouvertes.fr/hal-01950595
https://hal.archives-ouvertes.fr/hal-01950595
Publikováno v:
European journal of applied physiology. 113(3)
It has been suggested that circulating hormones and cytokines are important in the adaptive response to low-load resistance training (LLRT) with blood flow restriction (BFR); however, their response following this type of training in older men is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b7f44716032de64b0b7425ad5a65cd
https://pubmed.ncbi.nlm.nih.gov/22922803
https://pubmed.ncbi.nlm.nih.gov/22922803
Autor:
Trish Gorely, Gerry P McCann, Kamlesh Khunti, Anvesha Singh, Emma G. Wilmot, Jamal N Khan, Melanie J. Davies, Sven Plein, Myra A. Nimmo, Melanie Leggate, John D Biglands
Publikováno v:
Journal of Cardiovascular Magnetic Resonance
Background There is an epidemic of obesity and Type-2 Diabetes Mellitus (T2DM) in the developed world. Subclinical diastolic dysfunction in diabetes is associated with the development of overt heart failure. Although diabetic cardiomyopathy is well d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906c61d97ff7af901df0b40ec4418199
http://europepmc.org/articles/PMC3559451
http://europepmc.org/articles/PMC3559451