Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Melanie, Laschinger"'
Autor:
Anna-Marie Pedde, Hyunu Kim, Sainitin Donakonda, Tobias Baumann, Felix Bayerl, Philippa Meiser, Anna Hirschberger, Christine Klement, Simon Grassmann, Rupert Öllinger, Norbert Hüser, Daniel Hartmann, Melanie Laschinger, Joseph A. Trapani, Alfred Zippelius, Tobias Bald, Gabriela M. Wiedemann, Roland Rad, Joseph C. Sun, Bastian Höchst, Jan P. Böttcher
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114855- (2024)
Summary: Natural killer (NK) cells are critical for anti-metastatic immunity and can eliminate metastasizing tumor cells within circulation and sites of metastatic seeding. Here, we show that disseminated tumor cells (DTCs) colonizing the mouse lung
Externí odkaz:
https://doaj.org/article/f59733942ee14e7693060de6e6edd91a
Autor:
Xiaobo Wang, Rouzanna Istvanffy, Linhan Ye, Steffen Teller, Melanie Laschinger, Kalliope N. Diakopoulos, Kıvanç Görgülü, Qiaolin Li, Lei Ren, Carsten Jäger, Katja Steiger, Alexander Muckenhuber, Baiba Vilne, Kaan Çifcibaşı, Carmen Mota Reyes, Ümmügülsüm Yurteri, Maximilian Kießler, Ibrahim Halil Gürçınar, Maya Sugden, Saliha Elif Yıldızhan, Osman Uğur Sezerman, Sümeyye Çilingir, Güldal Süyen, Maximilian Reichert, Roland M. Schmid, Stefanie Bärthel, Rupert Oellinger, Achim Krüger, Roland Rad, Dieter Saur, Hana Algül, Helmut Friess, Marina Lesina, Güralp Onur Ceyhan, Ihsan Ekin Demir
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Solid cancers like pancreatic ductal adenocarcinoma (PDAC), a type of pancreatic cancer, frequently exploit nerves for rapid dissemination. This neural invasion (NI) is an independent prognostic factor in PDAC, but insufficiently modeled in genetical
Externí odkaz:
https://doaj.org/article/de6bfa94aa5043158c58f7d898718cfc
Autor:
Marcus Brugger, Melanie Laschinger, Sandra Lampl, Annika Schneider, Katrin Manske, Dena Esfandyari, Norbert Hüser, Daniel Hartmann, Katja Steiger, Stefan Engelhardt, Dirk Wohlleber, Percy A. Knolle
Publikováno v:
JHEP Reports, Vol 4, Iss 5, Pp 100465- (2022)
Background & Aims: Increased sensitivity towards tumor necrosis factor (TNF)-induced cell death in virus-infected hepatocytes has revealed a so far unrecognized hepatocyte-intrinsic antiviral immune surveillance mechanism, for which no in vitro or ex
Externí odkaz:
https://doaj.org/article/d30298ff222c47149b68e90c4a9b5176
Autor:
Yuhan Yin, Anna Sichler, Josef Ecker, Melanie Laschinger, Gerhard Liebisch, Marcus Höring, Marijana Basic, André Bleich, Xue-Jun Zhang, Ludwig Kübelsbeck, Johannes Plagge, Emely Scherer, Dirk Wohlleber, Jianye Wang, Yang Wang, Marcella Steffani, Pavel Stupakov, Yasmin Gärtner, Fabian Lohöfer, Carolin Mogler, Helmut Friess, Daniel Hartmann, Bernhard Holzmann, Norbert Hüser, Klaus-Peter Janssen
Publikováno v:
Journal of Hepatology. 78:820-835
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a25748f5bf50972b4dac2d6705f14b1
https://doi.org/10.1016/j.jhep.2022.12.028
https://doi.org/10.1016/j.jhep.2022.12.028
Autor:
Zhangjun Cheng, Lei Liu, Xue-Jun Zhang, Miao Lu, Yang Wang, Volker Assfalg, Melanie Laschinger, Guido von Figura, Yoshiaki Sunami, Christoph W. Michalski, Jörg Kleeff, Helmut Friess, Daniel Hartmann, Norbert Hüser
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a nuclear receptor demonstrated to play an important role in various biological processes. The aim of this study was to determine the effect of PPARγ on liver regeneration upon pa
Externí odkaz:
https://doaj.org/article/ecb71ae021a447b3b0068caed178e122
Autor:
Sarah Schulze, Christian Stöß, Miao Lu, Baocai Wang, Melanie Laschinger, Katja Steiger, Felicitas Altmayr, Helmut Friess, Daniel Hartmann, Bernhard Holzmann, Norbert Hüser
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Stimulation of cytosolic nucleic acid sensors of innate immunity by pathogen-derived nucleic acids is important for antimicrobial defence, but stimulation through self-derived nucleic acids may contribute to autoinflammation and cancer. DNA
Externí odkaz:
https://doaj.org/article/e23109e2d28a4177896768238a57e86e
Autor:
Güralp O. Ceyhan, Helmut Friess, Melanie Laschinger, Rupert Langer, Karen Becker, Matthias Maak, Tibor Schuster, Dominic Dischl, Timo Kehl, Kristina Kujundzic, Esra Yildiz, Alexandra Boldis, Robert Rosenberg, Ihsan Ekin Demir, Florian Liebl
Purpose: Neural invasion (NI) is a histopathologic feature of colon cancer that receives little consideration. Therefore, we conducted a morphologic and functional characterization of NI in colon cancer.Experimental Design: NI was investigated in 673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebc307e24a15e62889cc9d1dc5e9f54
https://doi.org/10.1158/1078-0432.c.6521829
https://doi.org/10.1158/1078-0432.c.6521829
Autor:
Güralp O. Ceyhan, Helmut Friess, Melanie Laschinger, Rupert Langer, Karen Becker, Matthias Maak, Tibor Schuster, Dominic Dischl, Timo Kehl, Kristina Kujundzic, Esra Yildiz, Alexandra Boldis, Robert Rosenberg, Ihsan Ekin Demir, Florian Liebl
PDF file - 62K, Supplementary Table with patient characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc6f6d72acdc6d781bdc43f15b00a59
https://doi.org/10.1158/1078-0432.22450026.v1
https://doi.org/10.1158/1078-0432.22450026.v1
Autor:
Marcella Steffani, Christian Stöss, Melanie Laschinger, Volker Assfalg, Sarah Schulze, Carolin Mogler, Fabian Lohöfer, Philipp Paprottka, Norbert Hüser, Helmut Friess, Daniel Hartmann, Alexander Novotny
Publikováno v:
HPB. 24:1362-1364
The first-line therapy for liver malignancies is a radical extended liver resection. This high-risk operation has a high incidence of post-hepatectomy liver failure (PHLF) due to a small future liver remnant (FLR). One of the procedures to increase t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb3660c75b5f1f4c451d6f46d3699c9
https://doi.org/10.1016/j.hpb.2022.02.007
https://doi.org/10.1016/j.hpb.2022.02.007
Autor:
Junika Pohl, Alexandra Georgieva, Julius Weber, Juliane Kager, Sebastian Deschler, Melanie Laschinger, Daniel Hartmann, JanPhilipp Böttcher, Norbert Hüser, RolandMichael Schmid, PercyAlexander Knolle, Katrin Böttcher
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5874bd06f45933c09788a42c3b6a0a76
https://doi.org/10.1055/s-0042-1760076
https://doi.org/10.1055/s-0042-1760076