Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melania Grottoli"'
Autor:
Ombretta Garbarino, Giulia Elda Valenti, Lorenzo Monteleone, Gabriella Pietra, Maria Cristina Mingari, Andrea Benzi, Santina Bruzzone, Silvia Ravera, Riccardo Leardi, Emanuele Farinini, Stefania Vernazza, Melania Grottoli, Barbara Marengo, Cinzia Domenicotti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundMalignant melanoma is the most lethal form of skin cancer which shows BRAF mutation in 50% of patients. In this context, the identification of BRAFV600E mutation led to the development of specific inhibitors like PLX4032. Nevertheless, alth
Externí odkaz:
https://doaj.org/article/b8c698a0f07f4ca591628ff66b119098
Autor:
Monica Parodi, Simonetta Astigiano, Paolo Carrega, Gabriella Pietra, Chiara Vitale, Laura Damele, Melania Grottoli, Maria de la Luz Guevara Lopez, Riccardo Ferracini, Giulia Bertolini, Ilaria Roato, Massimo Vitale, Paola Orecchia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Since the first studies, the mouse models have provided crucial support for the most important discoveries on NK cells, on their development, function, and circulation within normal and tumor tissues. Murine tumor models were initially set to study m
Externí odkaz:
https://doaj.org/article/0309575181784972bcbc9dc6dafb0a48
Autor:
Sabina Di Matteo, Enrico Munari, Piera Filomena Fiore, Silvia Santopolo, Camilla Sampaoli, Andrea Pelosi, Salem Chouaib, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, Stefan Ebert, Markus Machwirth, Dorothee Haas, Marco Pezzullo, Gabriella Pietra, Melania Grottoli, Stephanie Buart, Erwan Mortier, Enrico Maggi, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMelanoma is a lethal skin cancer, and the risk of developing it is increased by exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL-15), induced by the exposure of skin cells to UV rays, could also
Externí odkaz:
https://doaj.org/article/019fa5592eae43aba1002be803c63084
Autor:
Melania Grottoli, Paolo Carrega, Lodovica Zullo, Chiara Dellepiane, Giovanni Rossi, Francesca Parisi, Giulia Barletta, Linda Zinoli, Simona Coco, Angela Alama, Silvia Marconi, Monica Parodi, Paola Orecchia, Sara Bassi, Massimo Vitale, Maria Cristina Mingari, Ulrich Pfeffer, Carlo Genova, Gabriella Pietra
Publikováno v:
Cancers. 14:5046
Immune checkpoint inhibitors (ICIs) immunotherapy has represented a breakthrough in cancer treatment. Clinical use of ICIs has shown an acceptable safety profile and promising antitumor activity. Nevertheless, some patients do not obtain clinical ben