Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Melania Cusimano"'
1
Akademický článek
Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury
Autor: Melania Cusimano, Elena Brambilla, Alessia Capotondo, Donatella De Feo, Antonio Tomasso, Giancarlo Comi, Patrizia D’Adamo, Luca Muzio, Gianvito Martino
Publikováno v: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background Spinal cord injury (SCI) is a devastating condition mainly deriving from a traumatic damage of the spinal cord (SC). Immune cells and endogenous SC-neural stem cells (SC-NSCs) play a critical role in wound healing processes, altho
Externí odkaz: https://doaj.org/article/b9368f91e60b460da87e2902e93fee74
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2
Akademický článek
Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice.
Autor: Ravid Shechter, Anat London, Chen Varol, Catarina Raposo, Melania Cusimano, Gili Yovel, Asya Rolls, Matthias Mack, Stefano Pluchino, Gianvito Martino, Steffen Jung, Michal Schwartz
Publikováno v: PLoS Medicine, Vol 6, Iss 7, p e1000113 (2009)
BackgroundAlthough macrophages (MPhi) are known as essential players in wound healing, their contribution to recovery from spinal cord injury (SCI) is a subject of debate. The difficulties in distinguishing between different MPhi subpopulations at th
Externí odkaz: https://doaj.org/article/984621802b204291b59412b4a6853944
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4
Abstract PR13: Development of chimeric forms of IFN-alpha for 'on demand' in vivo cancer gene therapy
Autor: Melania Cusimano, Peter Angel, Barbara Costa, Anna Ranghetti, Tiziano Di Tomaso, Filippo Birocchi, Nadia Coltella, Luigi Naldini
Publikováno v: Cancer Immunology Research. 8:PR13-PR13
The immunosuppressive tumor microenvironment is a major hurdle for cancer therapy. Our lab previously developed a cell and gene therapy strategy for the tumor-targeted delivery of IFN-alpha based on the transduction of hematopoietic stem/progenitor c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::623f0f2ddc78173b1c9f78545fba3933
https://doi.org/10.1158/2326-6074.tumimm18-pr13
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5
Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis
Autor: Alessia Capotondo, Giancarlo Comi, Luca Muzio, Melania Cusimano, Roberto Furlan, Gianvito Martino, Annamaria Finardi, Martina Zambito, Jose Manuel Garcia-Manteiga, Chiara Rossi
Publikováno v: Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-16 (2018)
Microglia activation is a commonly pathological hallmark of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), a devastating disorder characterized by a selective motor neurons degeneration. Whether such activation might represe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c94bc5097a9b9a211963d9fd9cbe72c
http://europepmc.org/articles/PMC5833860
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6
Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury
Autor: Luca Muzio, Antonio Tomasso, Melania Cusimano, Patrizia D'Adamo, Donatella De Feo, Alessia Capotondo, Elena Brambilla, Gianvito Martino, Giancarlo Comi
Publikováno v: Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-14 (2018)
Spinal cord injury (SCI) is a devastating condition mainly deriving from a traumatic damage of the spinal cord (SC). Immune cells and endogenous SC-neural stem cells (SC-NSCs) play a critical role in wound healing processes, although both are ineffec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68f458b04c700df8aff5d8d15ad44f8
https://pubmed.ncbi.nlm.nih.gov/29475438
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8
Neurogenic and non neurogenic functions of endogenous neural stem cells
Autor: Gianvito Martino, Melania Cusimano, Erica Butti, Marco Bacigaluppi
Publikováno v: Frontiers in Neuroscience, Vol 8 (2014)
Frontiers in Neuroscience
Adult neurogenesis is a lifelong process that occurs in two main neurogenic niches of the brain, namely in the subventricular zone (SVZ) of the lateral ventricles and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. In the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88efdcd2a35984904ace62ca7ab1bf90
http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00092/full
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