Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Melania Capasso"'
Autor:
Melania Capasso, N. Ahmad Aziz
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/a4c7b355dd9343e1ba78468e21c2fd9d
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102559- (2023)
Summary: Protein synthesis, or mRNA translation, is the biological process through which genetic information stored in messenger RNAs is encoded into proteins. Here, we present an optimized protocol for assessing the translation rate in mouse adult m
Externí odkaz:
https://doaj.org/article/8c98f1f6414541d39a06571907cf0bfe
Autor:
Theodore S. Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C. Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y. Kim, David Gallego-Ortega, Tessa E. Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S. Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C. Donker, Harry J.M. Groen, Sukhwinder S. Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B. Schiller, Martijn C. Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J. Theis, Philip M. Hansbro, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112525- (2023)
Summary: Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in early disease stages remain ill defined. Chronic obstructive pulmonary disease (C
Externí odkaz:
https://doaj.org/article/de07677bc6c241f3a6d5cd66f2c12fd0
Autor:
David Coe, Thanushiyan Poobalasingam, Hongmei Fu, Fabrizia Bonacina, Guosu Wang, Valle Morales, Annalisa Moregola, Nico Mitro, Kenneth C.P. Cheung, Eleanor J. Ward, Suchita Nadkarni, Dunja Aksentijevic, Katiuscia Bianchi, Giuseppe Danilo Norata, Melania Capasso, Federica M. Marelli-Berg
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Voltage-gated hydrogen channel 1 (Hvcn1) is a voltage-gated proton channel, which reduces cytosol acidification and facilitates the production of ROS. The increased expression of this channel in some cancers has led to proposing Hvcn1 antagonists as
Externí odkaz:
https://doaj.org/article/a22c09e639a14cbb8d7cc29fcaebece0
Autor:
Francesca R. Delvecchio, Rachel E.A. Fincham, Sarah Spear, Andrew Clear, Marina Roy-Luzarraga, Frances R. Balkwill, John G. Gribben, Michele Bombardieri, Kairbaan Hodivala-Dilke, Melania Capasso, Hemant M. Kocher
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1543-1565 (2021)
Background and aims: The presence of tertiary lymphoid structures (TLSs) may confer survival benefit to patients with pancreatic ductal adenocarcinoma (PDAC), in an otherwise immunologically inert malignancy. Yet, the precise role in PDAC has not bee
Externí odkaz:
https://doaj.org/article/b635dee8c698441ab3175efcb13b1c08
Autor:
Dijue Sun, Urszula Stopka-Farooqui, Sayka Barry, Ezra Aksoy, Gregory Parsonage, Anna Vossenkämper, Melania Capasso, Xinyu Wan, Sherine Norris, Jennifer L. Marshall, Andrew Clear, John Gribben, Thomas T. MacDonald, Christopher D. Buckley, Márta Korbonits, Oliver Haworth
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1461-1471.e4 (2019)
Summary: B cell lymphoma-6 (BCL6) is highly expressed in germinal center B cells, but how its expression is maintained is still not completely clear. Aryl hydrocarbon receptor interacting protein (AIP) is a co-chaperone of heat shock protein 90. Dele
Externí odkaz:
https://doaj.org/article/0e7c48760a0e4810870ae935225004a8
Autor:
Sarah Spear, Juliana B. Candido, Jacqueline R. McDermott, Cristina Ghirelli, Eleni Maniati, Stephen A. Beers, Frances R. Balkwill, Hemant M. Kocher, Melania Capasso
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
B cells are salient features of pancreatic ductal adenocarcinoma (PDAC) tumors, yet their role in this disease remains controversial. Murine studies have indicated a protumoral role for B cells, whereas clinical data show tumor-infiltrating B cells a
Externí odkaz:
https://doaj.org/article/887b3c9ae24445558ccc4bfff2414f40
Autor:
Hongmei Fu, Maryam Jangani, Aleesha Parmar, Guosu Wang, David Coe, Sarah Spear, Inga Sandrock, Melania Capasso, Mark Coles, Georgina Cornish, Helena Helmby, Federica M. Marelli-Berg
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Protective immunity relies upon differentiation of T cells into the appropriate subtype required to clear infections and efficient effector T cell localization to antigen-rich tissue. Recent studies have highlighted the role played by subpopulations
Externí odkaz:
https://doaj.org/article/6a3e80255a4647e6a15854e3537eca09
Publikováno v:
Cellular and molecular life sciences 80(5), 126 (2023). doi:10.1007/s00018-023-04775-y
Microglia are the tissue-resident macrophage population of the brain, specialized in supporting the CNS environment and protecting it from endogenous and exogenous insults. Nonetheless, their function declines with age, in ways that remain to be full
Autor:
Frances R. Balkwill, Melania Capasso, Jonathan S. Serody, Michelle Lockley, Pedro R. Cutillas, Joanne Topping, Richard Thompson, Probir Chakravarty, Edmund H. Wilkes, Thomas Dowe, Steffen Böhm, Lisa Bixby, Benjamin G. Vincent, Eleni Maniati, Oliver Pearce, Anne Montfort
Age, disease stage and treatment of patients from the cohort used for plasma IgG1,2,3 and 4 dosage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238030a733a852283350e86e93f128cd
https://doi.org/10.1158/1078-0432.22465734
https://doi.org/10.1158/1078-0432.22465734