cGAS/cGAMP/STING signal propagation in the tumor microenvironment: Key role for myeloid cells in antitumor immunity.

Autor: Mekers, Vera E.¹ (AUTHOR), Kho, Vera M.¹ (AUTHOR), Ansems, Marleen¹ (AUTHOR), Adema, Gosse J.¹ (AUTHOR) Gosse.Adema@radboudumc.nl

Publikováno v: Radiotherapy & Oncology. Sep2022, Vol. 174, p158-167. 10p.

Mechanical high-intensity focused ultrasound creates unique tumor debris enhancing dendritic cell-induced T cell activation.

Autor: van den Bijgaart RJE; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands., Mekers VE; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands., Schuurmans F; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands., Raaijmakers TK; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands., Wassink M; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands., Veltien A; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands., Dumont E; Image Guided Therapy, Pessac, France., Heerschap A; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands., Fütterer JJ; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Robotics and Mechatronics, University of Twente, Enschede, Netherlands., Adema GJ; Radiotherapy & OncoImmunology Laboratory, Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2022 Dec 07; Vol. 13, pp. 1038347. Date of Electronic Publication: 2022 Dec 07 (Print Publication: 2022).