Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mekayla A. Storer"'
Autor:
Mekayla A. Storer, Freda D. Miller
Publikováno v:
Open Biology, Vol 10, Iss 9 (2020)
Digit tip regeneration is one of the few examples of true multi-tissue regeneration in an adult mammal. The key step in this process is the formation of the blastema, a transient proliferating cell mass that generates the different cell types of the
Externí odkaz:
https://doaj.org/article/678965b816b94bd78108944230177c5d
Autor:
Michael J. Borrett, Brendan T. Innes, Danielle Jeong, Nareh Tahmasian, Mekayla A. Storer, Gary D. Bader, David R. Kaplan, Freda D. Miller
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108022- (2020)
Summary: The transitions from developing to adult quiescent and activated neural stem cells (NSCs) are not well understood. Here, we use single-cell transcriptional profiling and lineage tracing to characterize these transitions in the murine forebra
Externí odkaz:
https://doaj.org/article/4ab5b1317c10427a8a85e94cdb00f12f
Autor:
Mekayla A. Storer, Denis Gallagher, Michael P. Fatt, Jaclin V. Simonetta, David R. Kaplan, Freda D. Miller
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1464-1480 (2018)
Summary: Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating levels
Externí odkaz:
https://doaj.org/article/413de4bec0704eb2b2049d3c965c3187
Autor:
Michael P, Fatt, Lina M, Tran, Gisella, Vetere, Mekayla A, Storer, Jaclin V, Simonetta, Freda D, Miller, Paul W, Frankland, David R, Kaplan
Publikováno v:
Stem Cell Reports. 17:259-275
Senescent cells are responsible, in part, for tissue decline during aging. Here, we focused on CNS neural precursor cells (NPCs) to ask if this is because senescent cells in stem cell niches impair precursor-mediated tissue maintenance. We demonstrat
Autor:
Bao Zhang, Peng He, John E Lawrence, Shuaiyu Wang, Elizabeth Tuck, Brian A Williams, Kenny Roberts, Vitalii Kleshchevnikov, Lira Mamanova, Liam Bolt, Krzysztof Polanski, Rasa Elmentaite, Eirini S Fasouli, Martin Prete, Xiaoling He, Nadav Yayon, Yixi Fu, Hao Yang, Chen Liang, Hui Zhang, Raphael Blain, Alain Chedotal, David R. FitzPatrick, Helen Firth, Andrew Dean, John C Marioni, Roger A Barker, Mekayla A Storer, Barbara J Wold, Hongbo Zhang, Sarah A Teichmann
Human limbs emerge during the fourth post-conception week as mesenchymal buds which develop into fully-formed limbs over the subsequent months. Limb development is orchestrated by numerous temporally and spatially restricted gene expression programme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89383041d1b982d74699809d6916ebe9
https://doi.org/10.1101/2022.04.27.489800
https://doi.org/10.1101/2022.04.27.489800
Autor:
Neemat, Mahmud, Christine, Eisner, Sruthi, Purushothaman, Mekayla A, Storer, David R, Kaplan, Freda D, Miller
Publikováno v:
Cell Reports. 41:111853
Here, we ask why the nail base is essential for mammalian digit tip regeneration, focusing on the inductive nail mesenchyme. We identify a transcriptional signature for these cells that includes Lmx1b and show that the Lmx1b-expressing nail mesenchym
Autor:
Aztekin, Can1 can.aztekin@epfl.ch, Storer, Mekayla A.2 ms2786@cam.ac.uk
Publikováno v:
Wound Repair & Regeneration. Nov2022, Vol. 30 Issue 6, p623-635. 13p.