Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mekala Sabarinathan"'
Autor:
Tsung Po Lai, Chenan Zhang, François Aguet, Justin Shinkle, Dayana A. Delgado, Brandon L. Pierce, Lin Chen, Meritxell Oliva, Jennifer A. Doherty, Kristin G. Ardlie, Sarah Kim-Hellmuth, Meytal Chernoff, Kathryn Demanelis, Eduardo Ramirez, Abraham Aviv, Hannah Lin, Habibul Ahsan, Lin Tong, Farzana Jasmine, Mekala Sabarinathan, Barbara E. Stranger, Muhammad G. Kibriya
Publikováno v:
Science
Telomere shortening is a hallmark of aging. Telomere length (TL) in blood cells has been studied extensively as a biomarker of human aging and disease; however, little is known regarding variability in TL in nonblood, disease-relevant tissue types. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2765f9c70f30a02e0693db0557bc048b
https://doi.org/10.1126/science.aaz6876
https://doi.org/10.1126/science.aaz6876
Autor:
Jianjun Gao, Muhammad Yunus, Alauddin Ahmed, Habibul Ahsan, Lin Tong, Golam Sarwar, Chenan Zhang, Brandon L. Pierce, Muhammad Rakibuz-Zaman, Kevin J. Gleason, Lin Chen, Farzana Jasmine, Mekala Sabarinathan, Jennifer A. Doherty, Maria Argos, Mahfuzar Rahman, Tariqul Islam, Justin Shinkle, Kathryn Demanelis, Muhammad G. Kibriya, Hasan Shahriar, Dayana A. Delgado, Shantanu Roy
Publikováno v:
Human Genetics. 138:49-60
Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability (h(2)): inherited variation in non-telomeric regions (e.g., SNPs that influence telomere maintenance) and variability in the lengths of telomeres in gamet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b277ce952c059f6e05016f409112a9d
https://doi.org/10.1007/s00439-018-1964-2
https://doi.org/10.1007/s00439-018-1964-2
Autor:
Hasan Shahriar, Shantanu Roy, Brandon L. Pierce, Tariqul Islam, Dayana A. Delgado, Mekala Sabarinathan, Alauddin Ahmed, Muhammad G. Kibriya, Jianjun Gao, Mahfuzar Rahman, Lin Chen, Justin Shinkle, Golam Sarwar, Mohammad Yunus, Chenan Zhang, Farzana Jasmine, Muhammad Rakibuz-Zaman, Maria Argos, Habibul Ahsan, Lin Tong
Publikováno v:
Journal of Medical Genetics
BackgroundLeucocyte telomere length (TL) is a potential biomarker of ageing and risk for age-related disease. Leucocyte TL is heritable and shows substantial differences by race/ethnicity. Recent genome-wide association studies (GWAS) report ~10 loci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3056ca76cc4b926edf355b247f3b224e
http://europepmc.org/articles/PMC5749304
http://europepmc.org/articles/PMC5749304
Autor:
Lin Chen, Maria Argos, Golam Sarwar, Muhammad Rakibuz-Zaman, Mekala Sabarinathan, Tariqul Islam, Mahfuzar Rahman, Muhammad G. Kibriya, Alauddin Ahmed, Yunus, Habibul Ahsan, Chenan Zhang, Brandon L. Pierce, Lin Tong, Justin Shinkle, Farzana Jasmine, Shantanu Roy, Hasan Shahriar, Jianjun Gao, Samantha G Dean, Joseph H. Graziano
Publikováno v:
Aging (Albany NY)
Telomeres are tandem repeat sequences at the end of chromosomes that bind proteins to protect chromosome ends. Telomeres shorten with age, and shorter leukocyte telomere length (TL) has been associated with overall mortality in numerous studies. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fbcf13206c4d4659c05e4376905a31
https://doi.org/10.18632/aging.101246
https://doi.org/10.18632/aging.101246
Autor:
Meytal Chernoff, Lin Chen, Hannah Lin, Habibul Ahsan, Mekala Sabarinathan, Barbara E. Stranger, Lin Tong, Farzana Jasmine, Sarah Kim-Hellmuth, Kristin G. Ardlie, Muhammad G. Kibriya, François Aguet, Eduardo Ramirez, Justin Shinkle, Kathryn Demanelis, Brandon L. Pierce, Jennifer A. Doherty, Meritxell Oliva
Telomere shortening is a hallmark of aging. Telomere length (TL) in blood cells has been studied extensively as a biomarker of human aging and disease; however, little is known regarding variability in TL in non-blood, disease-relevant tissue types.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29005813cd190bc6e5b7fa7ec1f3d696
Autor:
Maria Argos, Golam Sarwar, Justin Shinkle, Habibul Ahsan, Lin Tong, Hasan Shahriar, Muhammad Rakibuz-Zaman, Karin Engström, Mahfuzar Rahman, Mohammad Yunus, Brandon L. Pierce, Joseph H. Graziano, Kathryn Demanelis, Farzana Jasmine, Mekala Sabarinathan, Tariqul Islam, Karin Broberg
Publikováno v:
Environmental Health Perspectives
Arsenic exposure affects [Formula: see text] people worldwide, including [Formula: see text] in Bangladesh. Arsenic exposure increases the risk of cancer and other chronic diseases, and one potential mechanism of arsenic toxicity is epigenetic dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dcdc65d2fcf04b6dd012d01fca4c13
https://pubmed.ncbi.nlm.nih.gov/31135185
https://pubmed.ncbi.nlm.nih.gov/31135185
Autor:
Brandon L. Pierce, Mary V. Gamble, Kathryn Demanelis, Joseph H. Graziano, Anthony DiGiovanni, Maria Argos, Golam Sarwar, Justin Shinkle, Yunus, Farzana Jasmine, Mahfuzar Rahman, Hasan Shahriar, Habibul Ahsan, Lin Tong, Muhammad Rakibuz-Zaman, Tariqul Islam, Mekala Sabarinathan
Publikováno v:
Environmental Epidemiology (Philadelphia, Pa.)
Supplemental Digital Content is available in the text.
Background: Arsenic exposure affects >100 million people globally and increases risk for chronic diseases. One possible toxicity mechanism is epigenetic modification. Previous epigenome-wide
Background: Arsenic exposure affects >100 million people globally and increases risk for chronic diseases. One possible toxicity mechanism is epigenetic modification. Previous epigenome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d492c9d8e7bc28f292ca5f08e6871c8
https://doi.org/10.1097/ee9.0000000000000083
https://doi.org/10.1097/ee9.0000000000000083
Autor:
Farzana Jasmine, Kathryn Demanelis, Mohammad Yunus, Muhammad Rakibuz-Zaman, Justin Shinkle, Tariqul Islam, Golam Sarwar, Maria Argos, Habibul Ahsan, Brandon L. Pierce, Mahfuzar Rahman, Hasan Shahriar, Mekala Sabarinathan, Joseph Graziano, Lin Tong, Muhammad Kibriya
Publikováno v:
ISEE Conference Abstracts. 2018
Background: Arsenic exposure affects >200 million people worldwide, including ~56 million in Bangladesh. Arsenic exposure increases the risk of chronic disease, and one potential mechanism of ar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c1583a011100be6af74309379c2afc4
https://doi.org/10.1289/isesisee.2018.o03.01.12
https://doi.org/10.1289/isesisee.2018.o03.01.12
Autor:
Dayana A. Delgado, Justin Shinkle, Habibul Ahsan, Jianjun Gao, Brandon L. Pierce, Shantanu Roy, Rabiul Hasan, Tariqul Islam, Alauddin Ahmed, Md. Tariqul Islam, Chenan Zhang, Mekala Sabarinathan, Joseph H. Graziano, Mahbubul Eunus, Farzana Jasmine, Muhammad G. Kibriya
BACKGROUND: Chronic arsenic exposure is associated with increased risk for arsenical skin lesions, cancer, and other adverse health outcomes. One potential mechanism of arsenic toxicity is telomere dysfunction. However, prior epidemiological studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a808014818416190d3598491cf699c7
https://europepmc.org/articles/PMC6647858/
https://europepmc.org/articles/PMC6647858/
Autor:
Hasan Shahriar, Lin Chen, Mekala Sabarinathan, Dayana A. Delgado, Maria Argos, Jianjun Gao, Tariqul Islam, Mahfuzar Rahman, Jennifer A. Doherty, Chenan Zhang, Justin Shinkle, Muhammad Yunus, Alauddin Ahmed, Shantanu Roy, Brandon L. Pierce, Farzana Jasmine, Kathryn Demanelis, Golam Sarwar, Muhammad Rakibuz-Zaman, Habibul Ahsan, Lin Tong, Muhammad G. Kibriya
Leukocyte telomere length (LTL) is a heritable trait with two potential sources of heritability (h2): inherited variation in non-telomeric regions (e.g., SNPs that influence telomere maintenance) and variability in the lengths of telomeres in gametes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced232463b22f440545ef0020512ea4f