Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mekala R. Raman"'
Autor:
Sarah C. Conner, Matthew P. Pase, Herman Carneiro, Mekala R. Raman, Ann C. McKee, Victor E. Alvarez, Jamie M. Walker, Claudia L. Satizabal, Jayandra J. Himali, Thor D. Stein, Alexa Beiser, Sudha Seshadri
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 12, Pp 2403-2412 (2019)
Abstract Objective To determine whether vascular risk factor burden in mid‐ or late‐life associates with postmortem vascular and neurodegenerative pathologies in a community‐based sample. Methods We studied participants from the Framingham Hear
Externí odkaz:
https://doaj.org/article/82320af58984449f8dba3f30cff9e694
Autor:
Katharina Wittfeld, Mekala R. Raman, Sarah C. Conner, Asra Aslam, Alexander Teumer, Matthias Nauck, Norbert Hosten, Mohamad Habes, Charles DeCarli, Ramachandran S. Vasan, Alexa S. Beiser, Jayandra J. Himali, Sudha Seshadri, Hans J. Grabe, Claudia L. Satizabal
Publikováno v:
Journal of Alzheimer's disease 88(1), 311-322 (2022). doi:10.3233/JAD-220356
J Alzheimers Dis
Journal of Alzheimer's disease : JAD, vol 88, iss 1
J Alzheimers Dis
Journal of Alzheimer's disease : JAD, vol 88, iss 1
Background: Insulin-like growth factor 1 (IGF-1) signaling has been implicated in Alzheimer’s disease pathogenesis, and further evidence suggests inflammation can be a moderator of this association. However, most research to date has been conducted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46a8e8438bc1aeaf8d15a687f47493a
https://pub.dzne.de/record/164572
https://pub.dzne.de/record/164572
Autor:
Matthew P. Pase, Victor E. Alvarez, Claudia L. Satizabal, Herman Carneiro, Sarah C. Conner, Sudha Seshadri, Mekala R. Raman, Thor D. Stein, Alexa S. Beiser, Jayandra J. Himali, Jamie M. Walker, Ann C. McKee
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 12, Pp 2403-2412 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective To determine whether vascular risk factor burden in mid‐ or late‐life associates with postmortem vascular and neurodegenerative pathologies in a community‐based sample. Methods We studied participants from the Framingham Heart Study w
Autor:
Wendy M. White, Vesna D. Garovic, Julie A. Fields, Virginia M. Miller, Kent R. Bailey, Mekala R. Raman, Samantha M. Zuk, Michelle M. Mielke, Nirubol Tosakulwong, Kejal Kantarci, Clifford R. Jack, Timothy G. Lesnick, Matthew L. Senjem
Publikováno v:
Journal of Hypertension. 35:2479-2485
Objective Women with a history of preeclampsia are at an increased risk of hypertension and structural brain changes. However, the combined effect of both preeclampsia and late-life hypertension on brain structural changes is not known and was invest
Autor:
Matthew L. Senjem, Clifford R. Jack, Ronald C. Petersen, Bradley F. Boeve, Robert I. Reid, Jeffrey L. Gunter, David S. Knopman, Dennis W. Dickson, Samantha M. Zuk, Melissa E. Murray, Scott A. Przybelski, Mekala R. Raman, Timothy G. Lesnick, Joseph E. Parisi, Kejal Kantarci, Christopher G. Schwarz
Publikováno v:
Neurobiology of Aging. 56:172-179
Pattern of diffusion tensor MRI (DTI) alterations were investigated in pathologically-staged Alzheimer's disease (AD) patients (n = 46). Patients with antemortem DTI studies and a range of AD pathology at autopsy were included. Patients with a high n
Autor:
Jayandra J. Himali, Sudha Seshadri, Pauline Maillard, Claudia L. Satizabal, Alexa S. Beiser, Sarah C. Conner, Charles DeCarli, Mekala R. Raman, Ramachandran S. Vasan
Publikováno v:
Stroke, vol 49, iss 9
Background and Purpose— Little is known about associations between vascular growth factors and magnetic resonance imaging (MRI) markers in midlife. We investigated the association of serum VEGF (vascular endothelial growth factor), Ang2 (angiopoiet
Autor:
Christopher G. Schwarz, Kejal Kantarci, Val J. Lowe, Mekala R. Raman, Dennis W. Dickson, Melissa E. Murray, Clifford R. Jack
Publikováno v:
Journal of Neuroimaging
BACKGROUND AND PURPOSE Pathologic diagnosis is the gold standard in evaluating imaging measures developed as biomarkers for pathologically defined disorders. A brain MRI atlas representing autopsy-sampled tissue can be used to directly compare imagin
Publikováno v:
Magnetic Resonance in Medicine
Purpose Relaxation time constants are useful as markers of tissue properties. Imaging ex vivo tissue is done for research purposes; however, T1 relaxation time constants are altered by tissue fixation in a time-dependent manner. This study investigat
Publikováno v:
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Cerebrovascular pathologies (CVPs) are common pathologies associated with age-related cognitive decline along with Alzheimer disease pathologies. The impact of CVP on the prevalence of dementia is increasingly being recognized. The goal of this revie
Publikováno v:
Alzheimer's & Dementia. 14